Abstract: A circuit includes three battery groups. A first battery group is coupled to an input port. A negative electrode of a second battery group and a third battery group that are connected in parallel to each other is grounded, and a positive electrode of the second battery group and the third battery group is coupled to the first battery group through a switch. A negative electrode of the first battery group is further grounded through a switch. In addition, the input port is coupled to an output port through a buck circuit, the first battery group and the second battery group that are connected in parallel are coupled to an output of the buck circuit through a switch, and the first battery group is coupled to the output of the buck circuit through another switch. The output port is coupled to the output of the buck circuit.

Abstract: The present disclosure discloses use of polaprezinc (Pola) in preparing a drug for treating castration-resistant prostate cancer (CRPC) and belongs to the technical field of biological medicine. The present disclosure provides a new strategy for preparing the drug for treating the CRPC by combining the Pola with an androgen receptor antagonist for the first time and conducts a multi-angle and multi-level verification research. A drug composition combining the polaprezinc and the androgen receptor antagonist can be used for treating castration-resistant prostate cancer, remarkably improves an effect of enzalutamide in inhibiting the castration-resistant prostate cancer, realizes new use of the old drug, can greatly shorten time from drug discovery to clinical transformation, and has important clinical treatment significance.

Abstract: A handcuff structure, comprising a lock shell, a lock cover, a movable lock ring and a key; the side of the lock shell close to the lock cover is provided with a lock box; the inside of the lock box is provided with a rotating wheel, and the center of the rotating wheel is provided with a rotating shaft; one end of the rotating shaft extends into a first shaft hole at the bottom of the lock box, and the other end of the rotating shaft extends into a second shaft hole at the bottom of the lock cover; the first shaft hole and the second shaft hole are coaxially arranged. The invention can effectively prevent prisoners from opening handcuffs through wires, needles, wooden sticks and other items, avoid criminals from escaping, and improve the overall locking effect of handcuffs.

Abstract: An interventional operation isolation transfer cabin includes a cabin body, and a lead wire access device and a wire in/out device which two are mounted on the cabin body, the cabin body is provided with a negative pressure generating device at one end and an air inlet at the other end, the negative pressure generating device is provided with an exhaust filter device at its air outlet, and an intake filter device is provided at the air inlet. Several operating openings are provided on side walls of the cabin body, each of the operating openings is in seal connection with an operating glove, and a glove opening of at least one operating glove faces an interior of the cabin body. Equipment wires required by an interventional operation are preset through the lead wire access device, and wires added midway under a sealing condition is guaranteed through the wire in/out device.

Abstract: This document relates to budget-constrained index tuning in database systems. A method for index tuning within a database system includes receiving a budget constraint, generating a set of candidate indexes for a workload of queries, and determining a derived cost for each query-configuration pair (QCP). The method further involves identifying a subset of QCPs where the derived cost and a what-if cost have a delta value below a predefined difference threshold and allocating the budget constraint to these identified QCPs to avoid what-if calls. Additionally, the method reallocates a saved portion of the budget constraint to other QCPs where the delta value exceeds the difference threshold, evaluates these other QCPs using what-if calls to select an optimal index configuration, and applies the selected index configuration to the database system.

Abstract: The present disclosure provides an imaging system. The imaging system may include a detector including a detector including detecting modules arranged along the circumference direction of the imaging apparatus and configured to form the accommodation space; and a collimator including collimating modules arranged along the circumference direction and configured to rotate around the axis of the accommodation space that is perpendicular to the circumference direction. One of the collimating modules may include multiple collimating units in different configurations. The multiple collimating units may be arranged along the circumference direction. Each of the multiple collimating units may be switched between an effective state and an invalid state via a rotation of the collimator around the axis of the accommodation space.

Abstract: This document relates to budget-constrained index tuning in database systems. A method for index tuning within a database system includes receiving a budget constraint, generating a set of candidate indexes for a workload of queries, and determining a derived cost for each query-configuration pair (QCP). The method further involves identifying a subset of QCPs where the derived cost and a what-if cost have a delta value below a predefined difference threshold and allocating the budget constraint to these identified QCPs to avoid what-if calls. Additionally, the method reallocates a saved portion of the budget constraint to other QCPs where the delta value exceeds the difference threshold, evaluates these other QCPs using what-if calls to select an optimal index configuration, and applies the selected index configuration to the database system.

Abstract: An aerosol-forming product includes: a container, an accommodating cavity for accommodating an aerosol-forming material being formed in the container. The aerosol-forming product generates heat in a magnetic field to heat the aerosol-forming material. In an embodiment, the container is made of a sensor material. In an embodiment, the aerosol-forming product includes a heating element made of a sensor material.

Abstract: An atomizer includes: an aerosol-forming article having formed therein an accommodating cavity for accommodating an aerosol-forming substrate; and a suction nozzle assembly engaged with the aerosol-forming article, the suction nozzle assembly having an air inlet passage and an air outlet passage respectively in communication with the accommodating cavity and an assistance air passage directly or indirectly communicating the air outlet passage with external air.

Abstract: A handcuff structure, comprising a lock shell, a lock cover, a movable lock ring and a key; the side of the lock shell close to the lock cover is provided with a lock box; the inside of the lock box is provided with a rotating wheel, and the center of the rotating wheel is provided with a rotating shaft; one end of the rotating shaft extends into a first shaft hole at the bottom of the lock box, and the other end of the rotating shaft extends into a second shaft hole at the bottom of the lock cover; the first shaft hole and the second shaft hole are coaxially arranged. The invention can effectively prevent prisoners from opening handcuffs through wires, needles, wooden sticks and other items, avoid criminals from escaping, and improve the overall locking effect of handcuffs.

Abstract: A bicycle rear-wheel drive mechanism comprises a fixed shaft, a hollow toothed disc shaft, a wheel shaft, a sprocket shaft, an end cap and pin posts, the hollow toothed disc shaft is composed of a shaft cylinder and a toothed disc arranged at one end of the shaft cylinder, the toothed disc is provided with an array of semi-circular slots located at the edge of the disc body; in this design, the structure is stronger, the torque transmitted is greater, and the driving ability is stronger; replacing the original ball bearings used in bicycles with standardized tapered roller bearings allows the mechanism to be adjusted to the optimal axial and radial positions after installation, while also improving sealing performance and durability.

Abstract: The present application relates to a technical field of separating kavalactone and flavokawain, and in particular, to a method for separating flavokawain and kavalactone, kavalactone, and microencapsulated kavalactone. The separation method includes: S1. grinding root of piper methysticum, extracting by supercritical carbon dioxide and collecting a residue for later use, in which an extraction temperature is 45-50° C. and an extraction pressure is 4-8 MPa; S2. extracting the residue by supercritical carbon dioxide, and collecting extracted oil for later use, in which an extraction temperature is 60-80° C. and an extraction pressure is 20-50 MPa; S3. performing re-extraction and adsorption on the extracted oil to obtain a primary product of the kavalactone; and S4. crystallizing the primary product of kavalactone to obtain the kavalactone. The obtained kavalactone is used for microencapsulated kavalactone.

Abstract: The present disclosure relates to reduced sugar content white chocolate confectionery products comprising at least one rare sugar, such as allulose, methods of making the same wherein the confectionery products have desirable rheological properties, organoleptic properties, stable apparent viscosity, stable plastic viscosity, stable yield value, and coloring over time. The present disclosure also relates to preventing thickening or gelling of reduced sugar content white chocolate confectionery products comprising at least one rare sugar, such as allulose, during manufacturing, and maintaining stable apparent viscosity, stable plastic viscosity, and stable yield value over time.

Abstract: The invention proposes a kind of bending bolt type anti-loosening nut, which relates to the technical field of mechanical fastening. It comprises an upper nut and a lower nut, the upper nut and the lower nut are stacked on the outside of the bolt and used to tightly connect the bolt to the connecting piece, the lower nut is arranged close to the connecting piece, the upper nut is arranged on the outer end surface of the lower nut; the adjacent end between the upper nut and lower nut is provided with an inclined surface, the inclined surface is inclined towards the interior of the upper nut, so that an inclined plane angle with deformation space between the upper nut and lower nut is formed; the invention achieves the effect of preventing nut loosening, is low in price, easy to manufacture, and suitable for small or miniature anti-loosening nuts.

Abstract: Fried confectionery food products such as doughnuts and mini doughnuts, compositions, and methods for making wherein the confectionery food products have an extended shelf-life of from more than three (3) months up to nine (9) months where water activity, moisture loss and undesirable flavor and texture changes are controlled.

Abstract: The present disclosure relates to reduced sugar content milk chocolate confection and confectionery products comprising at least one rare sugar, such as allulose, methods of making the same wherein the confections and confectionery products have desirable rheological properties and organoleptic properties and stable viscosity over time. The present disclosure also relates to preventing thickening of reduced sugar content milk chocolate confections comprising at least one rare sugar, such as allulose, during manufacturing, and maintaining stable viscosity over time.

Abstract: The disclosure discloses a fatty acid synthase inhibitor and application thereof and belongs to the technical field of medical biology. The fatty acid synthase inhibitor of the disclosure can significantly inhibit the activity of fatty acid synthase without affecting normal expression, and adjust the ratio of fatty acids in cells. The fatty acid synthase inhibitor of the disclosure has a good tumor proliferation inhibitory effect, can arrest the growth cycle of tumor cells in the interphase, prevent tumor cell division, inhibit tumor cell proliferation, promote tumor cell apoptosis and exert a tumor treatment effect, can be used to treat tumors and metabolism related diseases, and has an important clinical application prospect.

Abstract: A dairy-free, gluten free and vegan chocolate confection and method of making the same are disclosed. In the chocolate confection of the invention, the milk solids present in traditional milk chocolate are replaced by heat-treated legume flour. The heat-treated legume flour imparts desirable flavor and texture characteristics to the chocolate confection. The legume flours have relatively low levels of sugar and high levels of protein and fiber. They are also suitable for reduced-sugar chocolate formulations.

Abstract: An interventional operation isolation transfer cabin includes a cabin body, and a lead wire access device and a wire in/out device which two are mounted on the cabin body, the cabin body is provided with a negative pressure generating device at one end and an air inlet at the other end, the negative pressure generating device is provided with an exhaust filter device at its air outlet, and an intake filter device is provided at the air inlet. Several operating openings are provided on side walls of the cabin body, each of the operating openings is in seal connection with an operating glove, and a glove opening of at least one operating glove faces an interior of the cabin body. Equipment wires required by an interventional operation are preset through the lead wire access device, and wires added midway under a sealing condition is guaranteed through the wire in/out device.

Abstract: The present disclosure relates to reduced sugar content milk chocolate confection and confectionery products comprising at least one rare sugar, such as allulose, methods of making the same wherein the confections and confectionery products have desirable rheological properties and organoleptic properties and stable viscosity over time. The present disclosure also relates to preventing thickening of reduced sugar content milk chocolate confections comprising at least one rare sugar, such as allulose, during manufacturing, and maintaining stable viscosity over time.