Abstract: Systems and methods for simultaneous network pruning and parameter optimization are disclosed. A method may include: (1) receiving a network to optimize, the network comprising a plurality of layers; (2) selecting layer pruning and/or channel pruning for the layers within the network; (3) providing a gating module at layers within the network, wherein each gating module opens or closes a gate in the gating module based on an output of a binary head; (4) training parameters for the network; (5) extracting gate open/close features from the gating modules; (6) optimizing a loss function for the network using a polarization regularizer to reach a consensus static sub-network; and (7) updating parameters for each gating module in the network consistent with the consensus static sub-network.

Abstract: Systems and methods for risk diagnosis of cryptocurrency addresses on blockchains using anonymous and public information are disclosed. In one embodiment, a method may include a risk diagnosis computer program executed by a server: receiving data with labels and data without labels from public data databases and/or anonymous data databases; fitting the data without labels into a plurality of clusters using unsupervised learning; assigning a risk level to each of the plurality of clusters; verifying the risk level for each of the plurality of clusters using the data with labels; receiving unseen data; and predicting a risk level associated with the unseen data by constructing features and text embeddings from the unseen data, clustering the unseen data based on a distance measurement to one of the plurality of clusters, and returning a risk level associated with the cluster.

Abstract: A test strip for detecting a serotype O foot-and-mouth disease, the test strip including: a bottom board; a detection layer being disposed on the bottom board and including a detection line and a control line; an absorbent layer being disposed at one end of the detection layer close to the control line; a gold colloidal conjugate pad being disposed at the other side of the detection layer close to the detection line; and a sample pad is disposed on a top of the gold colloidal conjugate pad. The gold colloidal conjugate pad is coated with colloidal gold particles that are conjugated with a Staphylococcus protein A (SPA) marker. The detection line is coated or impregnated with serotype O FMDV-like particles, and the control line is coated or impregnated with rabbit IgG.

Abstract: A method for preparing serotype O foot-and-mouth disease virus-like particles, the method including: construction of small ubiquitin-like modifier fusion expression vector, construction of recombinant expression vectors, construction of recombinant co-expression vector, expression and purification of proteins, and in-vitro assembly of serotype O foot-and-mouth disease virus-like particles. The disclosure also provides a test strip for detecting serotype O foot-and-mouth disease including a bottom board, and a detection layer disposed on the top of the bottom board. A detection line and a control line are disposed on the detection layer. An absorbent layer is disposed at one end of the detection layer close to the control line, and an immuno-gold pad is disposed at the other side of the detection layer close to the detection line. A sample pad is disposed on the top of the immuno-gold pad.

Abstract: A method for preparing serotype O foot-and-mouth disease virus-like particles, the method including: construction of small ubiquitin-like modifier fusion expression vector, construction of recombinant expression vectors, construction of recombinant co-expression vector, expression and purification of proteins, and in-vitro assembly of serotype O foot-and-mouth disease virus-like particles. The disclosure also provides a test strip for detecting serotype O foot-and-mouth disease including a bottom board, and a detection layer disposed on the top of the bottom board. A detection line and a control line are disposed on the detection layer. An absorbent layer is disposed at one end of the detection layer close to the control line, and an immuno-gold pad is disposed at the other side of the detection layer close to the detection line. A sample pad is disposed on the top of the immuno-gold pad.