Patents by Inventor Xiaoyu Lin

Xiaoyu Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combination therapy for treating cancer and diagnostic assays for use therein
    Patent number: 8624027
    Abstract: The present disclosure relates to a combination of therapeutic agents for use in treating a patient a subject suffering from cancer. In addition, the present disclosure also relates to diagnostic assays useful in classification of patients for treatment with one or more therapeutic agents.
    Type: Grant
    Filed: December 4, 2009
    Date of Patent: January 7, 2014
    Assignee: AbbVie Inc.
    Inventors: Omar Jameel Shah, Yu Shen, Xiaoyu Lin, Mark Anderson, Xiaoli Huang, Junling Li, Leiming Li
  • METHODS FOR ASSESSING THE DELIVERY OF EXOGENOUS AGENTS
    Publication number: 20100251392
    Abstract: This invention provides methods, compositions and kits for rapid determination of the delivery of exogenous agents both in vitro and in vivo, including without limitation siRNA, microRNA, a ribozyme or an antisence molecule, any of which may target, bind to, or inactivate the mRNA of the gene of interest expressed in the cells. The methods, compositions and kits utilize a promoter-reporter construct whereby successful non-viral nucleic acid delivery leads to an up-regulation of reporter signals thus providing a quantitative, sensitive and rapid means of detection, validation and monitoring.
    Type: Application
    Filed: May 2, 2008
    Publication date: September 30, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Yu Shen, Xiaoyu Lin, Stephen W. Fesik, Leiming Li
  • Combination Therapy for Treating Cancer and Diagnostic Assays for Use Therein
    Publication number: 20100227838
    Abstract: The present disclosure relates to a combination of therapeutic agents for use in treating a patient a subject suffering from cancer. In addition, the present disclosure also relates to diagnostic assays useful in classification of patients for treatment with one or more therapeutic agents.
    Type: Application
    Filed: December 4, 2009
    Publication date: September 9, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Omar Jameel Shah, Yu Shen, Xiaoyu Lin, Mark Anderson, Xiaoli Huang, Junling Li, Leiming Li
  • Methods for Assessing the Delivery of Exogenous Agents
    Publication number: 20100115635
    Abstract: This invention provides methods, compositions and kits for rapid determination of the delivery of exogenous agents both in vitro and in vivo, including without limitation siRNA, microRNA, a ribozyme or an antisense molecule, any of which may target, bind to, or inactivate the mRNA of the gene of interest expressed in the cells. The methods, compositions and kits utilize a promoter-reporter construct whereby successful non-viral nucleic acid delivery leads to an up-regulation of reporter signals thus providing a quantitative, sensitive and rapid means of detection, validation and monitoring.
    Type: Application
    Filed: March 31, 2009
    Publication date: May 6, 2010
    Applicant: Abbott Laboratories
    Inventors: Yu Shen, Stephen W. Fesik, Xiaoyu Lin, Leiming Li
  • Inducible expression systems for modulating the expression of target genes in eukaryotic cells and non-human animals
    Publication number: 20060031945
    Abstract: The present invention relates to inducible expression systems and to compositions and methods for modulating the expression of at least one target gene in an eukaryotic cell and non-human animal.
    Type: Application
    Filed: August 6, 2004
    Publication date: February 9, 2006
    Inventors: Yu Shen, Stephen Fesik, Xiaoyu Lin