Patents by Inventor Xiaoyu Shen
Xiaoyu Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240088354Abstract: A battery electrode includes a first metal foil, a second metal foil, and a thermoplastic polymer layer between the first metal foil and the second metal foil. The battery electrode also includes a first coating adjacent to the first metal foil such that the first metal foil is between the thermoplastic polymer layer and the first coating. The battery electrode also includes a second coating adjacent to the second metal foil such that the second metal foil is between the thermoplastic polymer layer and the second coating.Type: ApplicationFiled: September 9, 2022Publication date: March 14, 2024Inventors: Xiaoyun Yang, Aaron Smith, Wanjie Zhang, Siva Ram Kumar Muthukumar, Kai Yu, Enbang Wang, Yafeng Chen, Rohit Bedida, Xiaoyu Shen, Xingxing Zhang
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Patent number: 9694396Abstract: The present disclosure provides a stripping apparatus including a cleaning device, a transition unit and a stripping device. The cleaning device includes a first cleaning unit, a second cleaning unit and a third cleaning unit. The stripping device is connected with the transition unit; the transition unit is further connected with the first cleaning unit; the first cleaning unit is further connected with the second cleaning unit; the second cleaning unit is further connected with the third cleaning unit. Temperatures of the first cleaning unit, the second cleaning unit and the third cleaning unit are gradually decreased. The temperature of the third cleaning unit is equal to the temperature of water injected into the third cleaning unit.Type: GrantFiled: October 20, 2014Date of Patent: July 4, 2017Assignees: BOE TECHNOLOGY GROUP CO., LTD., BEIJING BOE DISPLAY TECHNOLOGY CO., LTD.Inventors: Zhixue Dong, Wei Li, Youngjin Song, Kai Yu, Zhongfei Bai, Qihui Wang, Yunliang Zheng, Meng Yang, Shuangqiang Zhang, Xiaoyu Shen
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Publication number: 20150336137Abstract: The present disclosure provides a stripping apparatus including a cleaning device, a transition unit and a stripping device. The cleaning device includes a first cleaning unit, a second cleaning unit and a third cleaning unit. The stripping device is connected with the transition unit; the transition unit is further connected with the first cleaning unit; the first cleaning unit is further connected with the second cleaning unit; the second cleaning unit is further connected with the third cleaning unit. Temperatures of the first cleaning unit, the second cleaning unit and the third cleaning unit are gradually decreased. The temperature of the third cleaning unit is equal to the temperature of water injected into the third cleaning unit.Type: ApplicationFiled: October 20, 2014Publication date: November 26, 2015Applicants: BOE TECHNOLOGY GROUP CO., LTD., BEIJING BOE DISPLAY TECHNOLOGY CO., LTD.Inventors: ZHIXUE DONG, WEI LI, YOUNGJIN SONG, KAI YU, ZHONGFEI BAI, QIHUI WANG, YUNLIANG ZHENG, MENG YANG, SHUANGQIANG ZHANG, XIAOYU SHEN
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Publication number: 20120190743Abstract: Compounds, pharmaceutical compositions and methods of treating a disorder or disease associated with neurokinin 2 (NK2) receptor activity.Type: ApplicationFiled: September 7, 2010Publication date: July 26, 2012Applicant: UNITED PARAGON ASSOCIATES INC.Inventors: Jerald Bain, Joel Sadavoy, Hao Chen, Xiaoyu Shen
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Publication number: 20030054537Abstract: A system has been constructed which is suitable for tetracycline-inducible gene expression in Gram-positive bacteria such as Staphylococcus aureus and Bacillus subtilis. The replicon/host gene expression system is tightly regulated, can be used in complex as well as minimal media, and can produce a high level of gene expression upon induction, with a variety of gene products. The gene expression system is suitable for production of products toxic to the host cells, and can be used, for example, for the analysis of gene expression and gene products in Gram-positive bacteria, and in a test of the effect of a peptide or polypeptide inhibitor of an S. aureus enzyme on the growth of S. aureus cells in culture or during infection of an animal.Type: ApplicationFiled: May 17, 2002Publication date: March 20, 2003Applicant: Cubist Pharmaceuticals, Inc.Inventors: Francis P. Tally, Jianshi Tao, Xiaoyu Shen, Jiansu Zhang
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Patent number: 6475726Abstract: The invention comprises methods useful within a larger process for identifying compounds and/or designing further compounds with activity to produce a desired phenotype (for example, growth inhibition) in cells whose target cell component is the subject of certain studies to identify such compounds. The invention employs constructed cells comprising a regulable gene encoding a biomolecule which modulates (inhibits or activates) in vivo the function of a target component of the cell which can be an enzyme, for example, methionyl-tRNA synthetase of Staphylococcus aureus. The process incorporates methods for identifying biomolecules that bind to a chosen target cell component in vitro, methods for identifying biomolecules that also bind to the chosen target and modulate its function intracellularly, causing a phenotypic effect.Type: GrantFiled: June 25, 1999Date of Patent: November 5, 2002Assignee: Cubist Pharmaceuticals, Inc.Inventors: Francis P. Tally, Jianshi Tao, Philip A. Wendler, Gene Connelly, Paul L. Gallant, Xiaoyu Shen, Jiansu Zhang
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Patent number: 6436694Abstract: A system has been constructed which is suitable for tetracycline-inducible gene expression in Gram-positive bacteria such as Staphylococcus aureus and Bacillus subtilis. The replicon/host gene expression system is tightly regulated, can be used in complex as well as minimal media, and can produce a high level of gene expression upon induction, with a variety of gene products. The gene expression system is suitable for production of products toxic to the host cells, and can be used, for example, for the analysis of gene expression and gene products in Gram-positive bacteria, and in a test of the effect of a peptide or polypeptide inhibitor of an S. aureus enzyme on the growth of S. aureus cells in culture or during infection of an animal.Type: GrantFiled: April 14, 1999Date of Patent: August 20, 2002Assignee: Cubist Pharmaceuticals, Inc.Inventors: Francis P. Tally, Jianshi Tao, Xiaoyu Shen, Jiansu Zhang
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Patent number: 6221640Abstract: Recombinant nucleic acids which encode aminoacyl-tRNA sythetases of enterococcal origin or portions of such enzymes, have been isolated. These nucleic acids can be used to make expression constructs and transformed host cells for the production of enterococcal aminoacyl-tRNA synthetases. They can also be used in the further isolation of nucleic acids related by DNA sequence similarities, which also encode enterococcal aminoacyl-tRNA synthetases, or portions thereof. A further embodiment of the invention is antisense nucleic acid which can hybridize to the nucleic acid which encodes the aminoacyl-tRNA synthetase of enterococci. The invention also relates to tRNA synthetases such as isolated and/or recombinant enterococcal aminoacyl-tRNA synthetases. Antibodies which bind to these enzymes can be made and can be used in the purification and study of the enzymes.Type: GrantFiled: May 14, 1997Date of Patent: April 24, 2001Assignee: Cubist Pharmaceuticals, Inc.Inventors: Jianshi Tao, Mandana Sassanfar, Paul L. Gallant, Xiaoyu Shen, Anthony S. Avruch, Russell V. Yu, Shamila Nair
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Candida cytoplasmic tryptophanyl-tRNA synthetase proteins, nucleic acids and strains comprising same
Patent number: 6174713Abstract: The present invention relates to isolated and/or recombinant nucleic acids which encode Candida cytoplasmic tryptophanyl-tRNA synthetases, portions thereof, or fusion proteins comprising a Candida cytoplasmic tryptophanyl-tRNA synthetase or portion thereof. Also disclosed are constructs comprising the nucleic acids of the present invention, host cells comprising a recombinant nucleic acid or construct, and methods of producing a Candida cytoplasmic tryptophanyl-tRNA synthetase, portion thereof, or fusion protein comprising the same. Also described are tester strains, which are cells engineered to rely on the function of a Candida cytoplasmic tryptophanyl-tRNA synthetase or functional fragment thereof encoded by an introduced cloned gene, and which can be used in a method of detecting an inhibitor of Candida cytoplasmic tryptophanyl-tRNA synthetase function.Type: GrantFiled: June 16, 1997Date of Patent: January 16, 2001Assignee: Cubist Pharmaceuticals, Inc.Inventors: Xiaoyu Shen, Fariba Houman -
Patent number: 5871987Abstract: The present invention relates to isolated and/or recombinant nucleic acids which encode Candida tyrosyl-tRNA synthetases, portions thereof, or fusion proteins comprising a Candida tyrosyl-tRNA synthetase or portion thereof. Also disclosed are constructs comprising the nucleic acids of the present invention, host cells comprising a recombinant nucleic acid or construct, and methods of producing a Candida tyrosyl-tRNA synthetase, portion thereof, or fusion protein comprising same. Also described are tester strains, which are cells engineered to rely on the function of a Candida tyrosyl-tRNA synthetase or functional fragment thereof encoded by an introduced cloned gene, and which can be used in a method of detecting an inhibitor of Candida tyrosyl-tRNA synthetase function.Type: GrantFiled: November 1, 1996Date of Patent: February 16, 1999Assignee: Cubist Pharmaceuticals, Inc.Inventors: Mandana Sassanfar, Paul L. Gallant, Xiaoyu Shen, Nianjun Tao, Jianshi Tao, Fariba Houman
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Patent number: 5801013Abstract: Recombinant nucleic acids which encode aminoacyl-tRNA sythetases of helicobacter origin have been isolated. These nucleic acids can be used to make expression constructs and transformed host cells for the production of helicobacter aminoacyl-tRNA synthetases. They can also be used in the further isolation of nucleic acids related by DNA sequence similarities, which also encode helicobacter aminoacyl-tRNA synthetases, or portions thereof. A further embodiment of the invention is antisense nucleic acid which can hybridize to the nucleic acid which encodes the aminoacyl-tRNA synthetase of helicobacter. The invention also relates to isolated and/or recombinant helicobacter aminoacyl-tRNA synthetases. Antibodies which bind to these enzymes can be made and can be used in the purification and study of the enzymes.Type: GrantFiled: May 26, 1995Date of Patent: September 1, 1998Assignee: Cubist Pharmaceuticals, Inc.Inventors: Jianshi Tao, Yan Qiu, Fariba Houman, Xiaoyu Shen, Paul R. Schimmel