Abstract: The present disclosure provides methods and systems for lesion region identification. The methods may include identifying a target region corresponding to at least one reference organ from a first medical image of a target subject. The methods may include determining, based on the target region, a reference threshold used for lesion detection. The methods may further include identifying, based on the reference threshold, a lesion region from the first medical image.

Abstract: In a method for multipath reflection correction of acoustic signals received at an ultrasonic sensor, acoustic signals are received at the ultrasonic sensor over a time of flight range. Characteristics of multipath reflection signals of received acoustic signals are determined, wherein the characteristics of the multipath reflection signals of the received acoustic signals comprise a relationship of primary signal contributions to multipath reflection signal contributions for the acoustic signals received at the ultrasonic sensor at a plurality of times of flight for a plurality of locations of the ultrasonic sensor. The characteristics of the multipath reflection signals of received acoustic signals are compared to the received acoustic signals.

Abstract: In a method for multipath reflection correction of acoustic signals received at an ultrasonic sensor, characteristics of multipath reflection signals of the ultrasonic sensor are accessed, wherein the characteristics of the multipath reflection signals include a relationship of primary signal contributions to multipath reflection signal contributions for acoustic signals received at the ultrasonic sensor at a plurality of times of flight for a plurality of locations of the ultrasonic sensor. Acoustic signals are received at the ultrasonic sensor over a time of flight range while a target is interacting with the ultrasonic sensor, wherein the acoustic signals include a primary signal contribution and a multipath reflection signal contribution. The characteristics of the multipath reflection signals are compared to received acoustic signals.

Abstract: A piezoelectric micromachined ultrasound transducer (PMUT) device may include a plurality of layers including a structural layer, a piezoelectric layer, and electrode layers located on opposite sides of the piezoelectric layer. Conductive barrier layers may be located between the piezoelectric layer and the electrodes to the prevent diffusion of the piezoelectric layer into the electrode layers.

Abstract: In a method for multipath reflection correction of acoustic signals received at an ultrasonic sensor, acoustic signals are received at the ultrasonic sensor over a time of flight range. Characteristics of multipath reflection signals of received acoustic signals are determined, wherein the characteristics of the multipath reflection signals of the received acoustic signals comprise a relationship of primary signal contributions to multipath reflection signal contributions for the acoustic signals received at the ultrasonic sensor at a plurality of times of flight for a plurality of locations of the ultrasonic sensor. The characteristics of the multipath reflection signals of received acoustic signals are compared to the received acoustic signals.

Abstract: In a method for receive beamforming using an array of ultrasonic transducers, a plurality of array positions comprising pluralities of ultrasonic transducers of the array of ultrasonic transducers is defined. A pixel capture operation is performed at each array position of the plurality of array positions. The pixel capture operation includes transmitting ultrasonic signals using a transmit beam pattern comprising ultrasonic transducers of the array of ultrasonic transducers, the transmit beam pattern for forming an ultrasonic beam toward a region of interest, and receiving reflected ultrasonic signals using a receive beam pattern comprising at least one ultrasonic transducer of the array of ultrasonic transducers. Received reflected ultrasonic signals are combined for a plurality of array positions overlapping the region of interest in a receive beamforming operation to generate a pixel for a reference array position of the plurality of array positions.

Abstract: In a method for multipath reflection correction of acoustic signals received at an ultrasonic sensor, characteristics of multipath reflection signals of the ultrasonic sensor are accessed, wherein the characteristics of the multipath reflection signals include a relationship of primary signal contributions to multipath reflection signal contributions for acoustic signals received at the ultrasonic sensor at a plurality of times of flight for a plurality of locations of the ultrasonic sensor. Acoustic signals are received at the ultrasonic sensor over a time of flight range while a target is interacting with the ultrasonic sensor, wherein the acoustic signals include a primary signal contribution and a multipath reflection signal contribution. The characteristics of the multipath reflection signals are compared to received acoustic signals.

Abstract: An ultrasonic sensor includes a two-dimensional array of ultrasonic transducers, wherein the two-dimensional array of ultrasonic transducers is substantially flat, a contact layer having a non-uniform thickness overlying the two-dimensional array of ultrasonic transducers, and an array controller configured to control activation of ultrasonic transducers during an imaging operation for imaging a plurality of pixels at a plurality of positions within the two-dimensional array of ultrasonic transducers.

Abstract: In a method for determining blood vessel characteristic change using an ultrasonic sensor, a plurality of ultrasonic signal transmit and receive operations are performed at a position overlying a blood vessel of a person using an ultrasonic sensor, where the plurality of ultrasonic signal transmit and receive operations generate a plurality of received signals. Depths of blood vessel walls are determined at the position for a plurality of time instances based on local maxima of a combination of an acoustic impedance mismatch and a motion characteristic based at least in part on the plurality of received signals. A change in a blood vessel characteristic is determined based at least in part on a difference between the depths of the blood vessel walls at the plurality of time instances.

Abstract: An ultrasonic sensor includes a two-dimensional array of ultrasonic transducers, wherein the two-dimensional array of ultrasonic transducers is substantially flat, a contact layer having a non-uniform thickness overlying the two-dimensional array of ultrasonic transducers, and an array controller configured to control activation of ultrasonic transducers during an imaging operation for imaging a plurality of pixels at a plurality of positions within the two-dimensional array of ultrasonic transducers.

Abstract: A piezoelectric micromachined ultrasound transducer (PMUT) device may include a plurality of layers including a structural layer, a piezoelectric layer, and electrode layers located on opposite sides of the piezoelectric layer. Conductive barrier layers may be located between the piezoelectric layer and the electrodes to the prevent diffusion of the piezoelectric layer into the electrode layers.

Abstract: The present invention describes a reduction type coenzyme Q10 powder, a composition thereof, and a preparation method thereof. The reduction type coenzyme Q10 powder is obtained by reacting an oxidation type coenzyme Q10 with the presence of a reducing agent, removing an organic solvent and other purities from a reaction solution after the reaction is finished to obtain an oil-soluble reduction type coenzyme Q10 liquid, and then directly performing prill formation with cold wind on an obtained reduction type coenzyme Q10 greasy substance. The obtained reduction type coenzyme Q10 powder has a lower crystallinity, and in a Cu-K[alpha] X-ray diffraction spectrum, has a strong peak at a diffraction angle 2[theta] being 18.9 DEG, and has a very strong absorption peak at a diffraction angle 2[theta] being 22.8 DEG.

Abstract: The present invention describes a reduction type coenzyme Q10 powder, a composition thereof, and a preparation method thereof. The reduction type coenzyme Q10 powder is obtained by reacting an oxidation type coenzyme Q10 with the presence of a reducing agent, removing an organic solvent and other purities from a reaction solution after the reaction is finished to obtain an oil-soluble reduction type coenzyme Q10 liquid, and then directly performing prill formation with cold wind on an obtained reduction type coenzyme Q10 greasy substance. The obtained reduction type coenzyme Q10 powder has a lower crystallinity, and in a Cu-K[alpha] X-ray diffraction spectrum, has a strong peak at a diffraction angle 2[theta] being 18.9 DEG, and has a very strong absorption peak at a diffraction angle 2[theta] being 22.8 DEG.

Abstract: Provided are a linezolid intermediate and the preparation method thereof and a method for synthesizing linezolid. The structure of the intermediate is shown as formula F2, wherein the compound is prepared by a condensation reaction of (S)—N-(3-chloro-2-hydroxy-1-propyl) acetamide and the compound shown in formula F4. In the preparation methods of the compound shown in formula F2 and linezolid, the reaction system is mild, side reactions are few and the product yield is high.

Abstract: The present invention relates to an intermediate (12) of lycopene of 2,6,10-trimethyl-1,1-dialkoxyl-3,5,9-undecantriene of formula, (12) and its intermediate of 4-methyl-5,5-dialkoxyl-1-pentenyl-1-phosphonic acid dialkyl ester of formula (10), and their preparation methods. The process route is simple, the starting materials are available easily, the cost is low, and it is valuable in industry.

Abstract: The present invention relates to 2,6,10-trimethyl-3,5,9-undecatrienyl-1-aldehyde represented by formula (3), and a method for preparing this intermediate. The process route of the present invention is simple, the starting materials are available easily, and the cost is low.

Abstract: Provided are a linezolid intermediate and the preparation method thereof and a method for synthesizing linezolid. The structure of the intermediate is shown as formula F2, wherein the compound is prepared by a condensation reaction of (S)—N—(3-chloro-2-hydroxy-1-propyl) acetamide and the compound shown in formula F4. In the preparation methods of the compound shown in formula F2 and linezolid, the reaction system is mild, side reactions are few and the product yield is high.

Abstract: The present invention relates to an intermediate (12) of lycopene of 2,6,10-trimethyl-1,1-dialkoxyl-3,5,9-undecantriene of formula, (12) and its intermediate of 4-methyl-5,5-dialkoxyl-1-pentenyl-1-phosphonic acid dialkyl ester of formula (10), and their preparation methods. The process route is simple, the starting materials are available easily, the cost is low, and it is valuable in industry.

Abstract: The present invention relates to 2,6,10-trimethyl-3,5,9-undecatrienyl-1-aldehyde represented by formula (3), and a method for preparing this intermediate. The process route of the present invention is simple, the starting materials are available easily, and the cost is low.