Abstract: A multi-disulfide-bond long-chain peptide with neuroprotective activity can reduce cellular calcium influx by inhibiting glutamate receptors to protect cortical neurons from excitotoxicity induced by glutamate. It can be an effective neuroprotective agent.

Abstract: Skill measurement systems and methods include interaction pairs and an interaction uncertainty. The interaction pairs are pairwise matches corresponding to instances of interactions between players. The interaction uncertainty variable corresponds to the instance of interaction and is based in part on the uncertainties of a player, player team, and/or gameplay aspects. The interaction pairs and interaction uncertainty are used to more accurately determine a skill rating of a player based in part on interaction data among gameplay data from a gameplay session of a video game.

Abstract: A Beclin 1-targeting stapled peptide and a pharmaceutical composition. The stapled peptide includes an amino acid sequence at least 66.7% identical to amino acid residues 191-205 of Beclin 1, an amino acid residue E195 and an amino acid residue N202 in the stapled peptide are connected by a hydrocarbon staple to stabilize the ?-helical structure of the stapled peptide. The hydrocarbon staple is located at a position in the stapled peptide closer to the Beclin1 coiled coil domain-stapled peptide binding interface, which can enhance the binding affinity of the stapled peptide to Beclin 1 by 10-30 fold. Compared to other autophagy inducers like rapamycin and Tat-Beclin 1 peptide, the optimized stapled peptide shows the unique profile of not only inducing autophagy but also significantly enhancing the endolysosomal degradation of cell surface oncogenic receptors EGFR and HER2 in HER2-positive cancer cells.

Abstract: A display panel driving method, a drive circuit thereof, and a display device. The method comprises: when determined that the picture to be displayed belongs to a high power consumption display picture, providing a touch control and display integrated circuit and power supply management circuit of the display panel with a second reference voltage that is amplified by a first reference voltage and that is provided by an external voltage source, and driving each pixel to ensure the normal display of the high power consumption display picture; and when determined that the picture to be displayed belongs to a low power consumption display picture, directly providing the first reference voltage to the touch control and display integrated circuit and power supply management circuit of the display panel, and driving each pixel within the display panel so as to ensure the normal display of the low power consumption picture.

Abstract: A multi-disulfide-bond long-chain peptide with neuroprotective activity can reduce cellular calcium influx by inhibiting glutamate receptors to protect cortical neurons from excitotoxicity induced by glutamate. It can be an effective neuroprotective agent.

Abstract: Skill measurement systems and methods include interaction pairs and an interaction uncertainty. The interaction pairs are pairwise matches corresponding to instances of interactions between players. The interaction uncertainty variable corresponds to the instance of interaction and is based in part on the uncertainties of a player, player team, and/or gameplay aspects. The interaction pairs and interaction uncertainty are used to more accurately determine a skill rating of a player based in part on interaction data among gameplay data from a gameplay session of a video game.

Abstract: A display panel driving method, a drive circuit thereof, and a display device. The method comprises: when determined that the picture to be displayed belongs to a high power consumption display picture, providing a touch control and display integrated circuit and power supply management circuit of the display panel with a second reference voltage that is amplified by a first reference voltage and that is provided by an external voltage source, and driving each pixel to ensure the normal display of the high power consumption display picture; and when determined that the picture to be displayed belongs to a low power consumption display picture, directly providing the first reference voltage to the touch control and display integrated circuit and power supply management circuit of the display panel, and driving each pixel within the display panel so as to ensure the normal display of the low power consumption picture.

Abstract: A light guide plate, a backlight module and a display device in the field of display technology are provided. The light guide plate includes a light guide plate body and a prism structure located at at least one end of the light guide plate body. The prism structure includes a light incident surface and at least one reflective surface, and incident light from the light incident surface is can be reflected by the at least one reflective surface into the light guide plate body.

Abstract: A parking management system and a parking management method are disclosed. The parking management system includes a control device and a parking space boundary indicating device. The control device is configured to acquire size information of a vehicle to be parked and information of the vacant area where no vehicle is parked in a parking lot, determine parking area information of the vehicle to be parked according to the size information and the information of the vacant area, and send the parking area information to the parking space boundary indicating device; the parking space boundary indicating device is configured to form parking space boundary lines by shedding light on a parking area according to the parking area information.

Abstract: The present disclosure generally relates to display technologies. A liquid crystal display panel includes: a light guide layer having a first refractive index, a refractive layer on the light guide layer, a first polarizing layer on the refractive layer, a color filter layer on the first polarizing layer, a liquid crystal layer on the color filter layer, and an array substrate on the liquid crystal layer. The refractive layer includes a plurality of higher refractive index portions having a second refractive index and a plurality of lower refractive index portions having a third refractive index, the plurality of higher refractive index portions and the plurality of lower refractive index portions being arranged in an alternating manner. The liquid crystal display panel is configured to emit light substantially through the higher refractive index portions of the refractive layer.

Abstract: A light guide plate assembly, includes a light conductive layer and a plurality of light exit structures. The light conductive layer is configured to cause light entering the light conductive layer to be transmitted between two opposite surfaces of the light conductive layer. The plurality of light exit structures are disposed on one of the two opposite surfaces and spaced apart. The plurality of light exit structures are configured to enable a portion of the light to emit from the light conductive layer.

Abstract: The present disclosure generally relates to display technologies. A liquid crystal display panel includes: a light guide layer having a first refractive index, a refractive layer on the light guide layer, a first polarizing layer on the refractive layer, a color filter layer on the first polarizing layer, a liquid crystal layer on the color filter layer, and an array substrate on the liquid crystal layer. The refractive layer includes a plurality of higher refractive index portions having a second refractive index and a plurality of lower refractive index portions having a third refractive index, the plurality of higher refractive index portions and the plurality of lower refractive index portions being arranged in an alternating manner. The liquid crystal display panel is configured to emit light substantially through the higher refractive index portions of the refractive layer.

Abstract: A shift register unit is provided, which includes an input circuit, a first output circuit and a first output signal adjustment circuit. The input circuit is configured for receiving an input signal from an input terminal and controlling an electrical signal of a first node based on the input signal. The first output circuit is configured for outputting a first output signal at a first output terminal of the shift register unit based on a first clock signal under control of the electrical signal of the first node. The first output signal adjustment circuit is configured for providing a first reference signal to the first output terminal under control of the second clock signal so as to decrease an amplitude of the first output signal.

Abstract: The present disclosure provides a rapid passing method and device for a target vehicle. The rapid passing method for the target vehicle includes: determining a passing route of the target vehicle according to a place where the target vehicle is located and a destination; acquiring position information of the target vehicle in real time; and controlling lane indicating devices in the passing route to indicate a special-purpose lane used by the target vehicle in the passing route according to the real-time position information and the passing route of the target vehicle, and controlling traffic lights to indicate vehicles disturbing passing of the target vehicle to stop driving when the target vehicle passes through an intersection.

Abstract: A parking management system and a parking management method are disclosed. The parking management system includes a control device and a parking space boundary indicating device. The control device is configured to acquire width size information of a vehicle to be parked and information of the vacant area where no vehicle is parked in a parking lot, determine parking area information of the vehicle to be parked according to the width size information and the information of the vacant area, and send the parking area information to the parking space boundary indicating device; the parking space boundary indicating device is configured to form parking space boundary lines by shedding light on a parking area according to the parking area information.

Abstract: The present disclosure provides a display substrate, a method for preparing the same, and a display motherboard. The display substrate comprises: a plurality of display areas spaced apart from each other, each of which is provided with a plurality of spacers; and a blank area between any two adjacent display areas of the plurality of display areas, and provided with a plurality of supporters having the same material and height as the spacers. Since the blank area is provided with the supporters in the display substrate of this disclosure, the problem with uneven cell gap between the blank area and the display area under an action of atmospheric pressure is effectively avoided, thereby preventing the phenomenon that the display motherboard at a place with a greater cell gap presents a yellow color when displaying.

Abstract: There are provided a shift register unit and a driving method thereof. The shift register unit includes: an input circuit, whose first terminal receives an input signal of the shift register unit, and second terminal is connected to a pull-up node, the input circuit being configured to output the input signal to the pull-up node; an output circuit, whose first terminal is connected to a clock signal terminal, second terminal is connected to the pull-up node, third terminal is connected to an output terminal of the shift register unit, the output circuit being configured to output a signal of the clock signal terminal to the output terminal under the control of the pull-up node; a pull-up node control circuit, and the pull-up node control circuit being configured to discharge the pull-up node through third power supply voltage terminal under the control of a first power supply voltage terminal.

Abstract: A light guide plate assembly, includes a light conductive layer and a plurality of light exit structures. The light conductive layer is configured to cause light entering the light conductive layer to be transmitted between two opposite surfaces of the light conductive layer. The plurality of light exit structures are disposed on one of the two opposite surfaces and spaced apart. The plurality of light exit structures are configured to enable a portion of the light to emit from the light conductive layer.

Abstract: A light guide plate, a backlight module and a display device in the field of display technology are provided. The light guide plate includes a light guide plate body and a prism structure located at at least one end of the light guide plate body. The prism structure includes a light incident surface and at least one reflective surface, and incident light from the light incident surface is can be reflected by the at least one reflective surface into the light guide plate body.

Abstract: A shift register unit is provided, which includes an input circuit, a first output circuit and a first output signal adjustment circuit. The input circuit is configured for receiving an input signal from an input terminal and controlling an electrical signal of a first node based on the input signal. The first output circuit is configured for outputting a first output signal at a first output terminal of the shift register unit based on a first clock signal under control of the electrical signal of the first node. The first output signal adjustment circuit is configured for providing a first reference signal to the first output terminal under control of the second clock signal so as to decrease an amplitude of the first output signal.