Patents by Inventor Xiashi LV

Xiashi LV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ATX INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20230295159
    Abstract: Disclosed are an ATX inhibitor, a preparation method therefor, and the use thereof, which belong to the technical field of pharmaceutical chemistry. In particular, the ATX inhibitor is a compound having the structure of formula I?, or a pharmaceutically acceptable salt, an ester, an isomer, a solvate, a prodrug or an isotope marker thereof. Compared with the existing ATX inhibitor GLPG-1690, the ATX inhibitor has higher inhibitory activity, also has excellent efficacy, in vitro/in vivo pharmacokinetic properties and safety, and has broad clinical application prospects.
    Type: Application
    Filed: July 8, 2021
    Publication date: September 21, 2023
    Inventors: Cheng PENG, Mengfei QIAN, Xiashi LV, Jin WU, Wei YIN, Fengyou LIU, Yi JIN, Gang ZOU, Haiqing YUAN, Zhen Jim WU
  • SYNTHESIS AND APPLICATION OF CLASS OF RESPIRATORY SYNCYTIAL VIRUS INHIBITORS
    Publication number: 20230090060
    Abstract: The present disclosure provides the synthesis and application of respiratory syncytial virus inhibitor, being a compound of formula I or a pharmaceutically acceptable salt, ester, isomer, solvate, prodrug or isotope label thereof. Compared with the existing inhibitors, the compounds of formula I have the advantages of superior activity and higher exposure in vivo.
    Type: Application
    Filed: January 21, 2021
    Publication date: March 23, 2023
    Inventors: Cheng PENG, Xiashi LV, Mengfei QIAN, Wei YIN, Chaojun GONG, Jian HAN, Wei SHEN, Danbin LI, Gang ZOU, Haiqing YUAN, Zhen Jim WU
  • Dihydroisoquinoline compound
    Patent number: 10717730
    Abstract: Compositions containing the compound of general formula I: are disclosed. The compositions be used to prevent or treat hepatitis B virus infection.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: July 21, 2020
    Assignee: SUZHOU ARK BIOPHARMACEUTICAL CO., LTD.
    Inventors: Cheng Peng, Yang Zhou, Gang Zou, Danbin Li, Haiqing Yuan, Zhen Jim Wu, Xiashi Lv, Xiaogang Lai, Shaoyun Zhang
  • DIHYDROISOQUINOLINE COMPOUND
    Publication number: 20200207755
    Abstract: Compositions containing the compound of general formula I: are disclosed. The compositions be used to prevent or treat hepatitis B virus infection.
    Type: Application
    Filed: March 11, 2020
    Publication date: July 2, 2020
    Inventors: Cheng PENG, Xiashi LV, Xiaogang LAI, Shaoyun ZHANG, Yang ZHOU, Gang ZOU, Danbin LI, Haiqing YUAN, Zhen Jim WU
  • Dihydroisoquinoline compound
    Patent number: 10647712
    Abstract: A compound of general formula I: is disclosed. The compound be used to prevent or treat hepatitis B virus infection.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: May 12, 2020
    Assignee: SUZHOU ARK BIOPHARMACEUTICAL CO., LTD.
    Inventors: Cheng Peng, Qing Xu, Teng Feng, Xiashi Lv, Xiaogang Lai, Rui Cui, Shaoyun Zhang, Jian Han, Chaojun Gong, Zhaoxiong Cai, Yang Zhou, Gang Zou, Danbin Li, Haiqing Yuan, Zhen Jim Wu
  • DIHYDROISOQUINOLINE COMPOUND
    Publication number: 20190389855
    Abstract: A compound of general formula I: is disclosed. The compound be used to prevent or treat hepatitis B virus infection.
    Type: Application
    Filed: January 10, 2018
    Publication date: December 26, 2019
    Inventors: Cheng PENG, Qing XU, Teng FENG, Xiashi LV, Xiaogang LAI, Rui CUI, Shaoyun ZHANG, Jian HAN, Chaojun GONG, Zhaoxiong CAI, Yang ZHOU, Gang ZOU, Danbin LI, Haiqing YUAN, Zhen Jim WU