Patents by Inventor Xichao Wang

Xichao Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10544147
    Abstract: The instant invention provides compounds of formula (I) which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: January 28, 2020
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Abdelghani Abe Achab, Matthew P. Christopher, Francesc Xavier Fradera Llinas, Jason D. Katz, Joey L. Methot, Hua Zhou, Shimin Xu, Jianmin Fu, Ning Fu, Yabin Li, Xichao Wang
  • Publication number: 20190119278
    Abstract: The instant invention provides compounds of formula (I) which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.
    Type: Application
    Filed: March 24, 2017
    Publication date: April 25, 2019
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Abdelghani Abe Achab, Matthew P. Christopher, Francesc Xavier Fradera Llinas, Jason D. Katz, Joey L. Methot, Hua Zhou, Shimin Xu, Jianmin Fu, Ning Fu, Yabin Li, Xichao Wang
  • Patent number: 10017436
    Abstract: The present invention provides a method of making 1,1,1,2,3-pentachloropropane comprising: (1) utilizing 1,1,1,3-tetrachloropropane as a raw material and 1,1,1,2,3-pentachloropropane as a solvent to carry out a dehydrochlorination reaction to obtain 1,1,3-trichloropropene, and after the reaction, (2) introducing chlorine gas into the reaction system to carry out a chlorination reaction to obtain 1,1,1,2,3-pentachloropropane. In the present invention, 1,1,1,2,3-pentachloropropane acts as a solvent or a diluent, and may act as an inhibitor to prevent the production of high-boiling residues such as dimers, oligomers or polymers during the dehydrochlorination process. Then, the conversion rate of 1,1,1,3-tetrachloropropane is increased, and consequently, the yield of final product 1,1,1,2,3-pentachloropropane is also increased.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: July 10, 2018
    Assignee: Jiangxi Tianyu Chemical Co., Ltd.
    Inventors: Zhong Zhou, Haipeng Xu, Yiming Yu, Peng Peng, Yaling Zhao, Xichao Wang, Xiaori Yue