Patents by Inventor Xie Chen

Xie Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12020694
    Abstract: The computing system trains an end-to-end (E2E) automatic speech recognition (ASR) model, using a transformer-transducer-based deep neural network that comprises a transformer encoder network and a transducer predictor network. The E2E ASR model is trained to have one or more adjustable hyperparameters that are configured to dynamically adjust an efficiency or a performance of the E2E ASR model when the E2E ASR model is deployed onto a device or executed by the device, by identifying one or more conditions of the device associated with computational power of the device and setting at least one of the one or more adjustable hyperparameters based on one or more conditions of the device.
    Type: Grant
    Filed: June 8, 2023
    Date of Patent: June 25, 2024
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Yu Wu, Jinyu Li, Shujie Liu, Xie Chen, Chengyi Wang
  • Publication number: 20230317063
    Abstract: The computing system trains an end-to-end (E2E) automatic speech recognition (ASR) model, using a transformer-transducer-based deep neural network that comprises a transformer encoder network and a transducer predictor network. The E2E ASR model is trained to have one or more adjustable hyperparameters that are configured to dynamically adjust an efficiency or a performance of the E2E ASR model when the E2E ASR model is deployed onto a device or executed by the device, by identifying one or more conditions of the device associated with computational power of the device and setting at least one of the one or more adjustable hyperparameters based on one or more conditions of the device.
    Type: Application
    Filed: June 8, 2023
    Publication date: October 5, 2023
    Inventors: Yu WU, Jinyu LI, Shujie LIU, Xie CHEN, Chengyi WANG
  • Patent number: 11715462
    Abstract: A computing system is configured to generate a transformer-transducer-based deep neural network. The transformer-transducer-based deep neural network comprises a transformer encoder network and a transducer predictor network. The transformer encoder network has a plurality of layers, each of which includes a multi-head attention network sublayer and a feed-forward network sublayer. The computing system trains an end-to-end (E2E) automatic speech recognition (ASR) model, using the transformer-transducer-based deep neural network. The E2E ASR model has one or more adjustable hyperparameters that are configured to dynamically adjust an efficiency or a performance of E2E ASR model when the E2E ASR model is deployed onto a device or executed by the device.
    Type: Grant
    Filed: April 29, 2021
    Date of Patent: August 1, 2023
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Yu Wu, Jinyu Li, Shujie Liu, Xie Chen, Chengyi Wang
  • Patent number: 11629150
    Abstract: This invention is in the area of synthesizing pyrimidine-based compounds useful in the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: April 18, 2023
    Assignee: G1 Therapeutics, Inc.
    Inventors: Alexander Smith, Hannah S. White, Francis Xavier Tavares, Sergiy Krasutsky, Jian-Xie Chen, Roberta L. Dorrow, Hua Zhong
  • Publication number: 20230104647
    Abstract: Provided in this disclosure are methods for the synthesis of substituted 2-arylcyclopropylamines and 2-heteroarylcyclopropylamines and related compounds. Also provided are methods for reduction of thioesters to aldehydes, and methods for reductive amination of cyclopropylamines.
    Type: Application
    Filed: June 15, 2022
    Publication date: April 6, 2023
    Inventors: Amy E. TAPPER, Cassandra CELATKA, Arthur Glenn ROMERO, John M. MCCALL, Toni CHANCELLOR, Jian-Xie CHEN, Xuemei CHEN, He ZHAO, Betina BIOLATTO, Elisabeth C.A. BROT, Zhihua LI, Xiaoming LIAO
  • Patent number: 11527238
    Abstract: A computer device is provided that includes one or more processors configured to receive an end-to-end (E2E) model that has been trained for automatic speech recognition with training data from a source-domain, and receive an external language model that has been trained with training data from a target-domain. The one or more processors are configured to perform an inference of the probability of an output token sequence given a sequence of input speech features. Performing the inference includes computing an E2E model score, computing an external language model score, and computing an estimated internal language model score for the E2E model. The estimated internal language model score is computed by removing a contribution of an intrinsic acoustic model. The processor is further configured to compute an integrated score based at least on E2E model score, the external language model score, and the estimated internal language model score.
    Type: Grant
    Filed: January 21, 2021
    Date of Patent: December 13, 2022
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Zhong Meng, Sarangarajan Parthasarathy, Xie Sun, Yashesh Gaur, Naoyuki Kanda, Liang Lu, Xie Chen, Rui Zhao, Jinyu Li, Yifan Gong
  • Publication number: 20220351718
    Abstract: A computing system is configured to generate a transformer-transducer-based deep neural network. The transformer-transducer-based deep neural network comprises a transformer encoder network and a transducer predictor network. The transformer encoder network has a plurality of layers, each of which includes a multi-head attention network sublayer and a feed-forward network sublayer. The computing system trains an end-to-end (E2E) automatic speech recognition (ASR) model, using the transformer-transducer-based deep neural network. The E2E ASR model has one or more adjustable hyperparameters that are configured to dynamically adjust an efficiency or a performance of E2E ASR model when the E2E ASR model is deployed onto a device or executed by the device.
    Type: Application
    Filed: April 29, 2021
    Publication date: November 3, 2022
    Inventors: Yu WU, Jinyu LI, Shujie LIU, Xie CHEN, Chengyi WANG
  • Patent number: 11390590
    Abstract: Provided in this disclosure are methods for the synthesis of substituted 2-arylcyclopropylamines and 2-heteroarylcyclopropylamines and related compounds. Also provided are methods for reduction of thioesters to aldehydes, and methods for reductive animation of cyclopropylamines.
    Type: Grant
    Filed: August 16, 2017
    Date of Patent: July 19, 2022
    Assignee: Imago Biosciences, Inc.
    Inventors: Amy E. Tapper, Cassandra Celatka, Arthur Glenn Romero, John M. McCall, Toni Chancellor, Jian-Xie Chen, Xuemei Chen, He Zhao, Betina Biolatto, Elisabeth C. A. Brot, Zhihua Li, Xiaoming Liao
  • Publication number: 20220139380
    Abstract: A computer device is provided that includes one or more processors configured to receive an end-to-end (E2E) model that has been trained for automatic speech recognition with training data from a source-domain, and receive an external language model that has been trained with training data from a target-domain. The one or more processors are configured to perform an inference of the probability of an output token sequence given a sequence of input speech features. Performing the inference includes computing an E2E model score, computing an external language model score, and computing an estimated internal language model score for the E2E model. The estimated internal language model score is computed by removing a contribution of an intrinsic acoustic model. The processor is further configured to compute an integrated score based at least on E2E model score, the external language model score, and the estimated internal language model score.
    Type: Application
    Filed: January 21, 2021
    Publication date: May 5, 2022
    Applicant: Microsoft Technology Licensing, LLC
    Inventors: Zhong MENG, Sarangarajan PARTHASARATHY, Xie SUN, Yashesh GAUR, Naoyuki KANDA, Liang LU, Xie CHEN, Rui ZHAO, Jinyu LI, Yifan GONG
  • Patent number: 11295172
    Abstract: Method of detecting objects in non-perspective images starts by generating an arrangement of tiles based on a field of view of a non-perspective camera lens, a predetermined size of the tiles, and a predetermined maximum object radius. The arrangement of the tiles includes the minimum number of tiles to cover the field of view. A non-perspective image is then captured using the non-perspective camera lens. The non-perspective image may be a still image frame or a video. Using the tiles, a plurality of images are generated, respectively, and at least a portion of a first object is detected in one or more images. The first object is generated using the one or more images that include the at least the portion of the first object, and the first object is displayed on a display interface. Other embodiments are described herein.
    Type: Grant
    Filed: May 21, 2019
    Date of Patent: April 5, 2022
    Assignee: Snap Inc.
    Inventors: Kevin Xie Chen, Shree K. Nayar
  • Patent number: 11257484
    Abstract: According to some embodiments, a multi-layer speech recognition transcript post processing system may include a data-driven, statistical layer associated with a trained automatic speech recognition model that selects an initial transcript. A rule-based layer may receive the initial transcript from the data-driven, statistical layer and execute at least one pre-determined rule to generate a first modified transcript. A machine learning approach layer may receive the first modified transcript from the rule-based layer and perform a neural model inference to create a second modified transcript. A human editor layer may receive the second modified transcript from the machine learning approach layer along with an adjustment from at least one human editor. The adjustment may create, in some embodiments, a final transcript that may be used to fine-tune the data-driven, statistical layer.
    Type: Grant
    Filed: August 21, 2019
    Date of Patent: February 22, 2022
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Dimitrios Basile Dimitriadis, Xie Chen, Nanshan Zeng, Yu Shi, Liyang Lu
  • Publication number: 20220025424
    Abstract: The present disclosure relates to compositions and methods for producing stereoisomerically pure aminocyclopropanes.
    Type: Application
    Filed: August 16, 2017
    Publication date: January 27, 2022
    Inventors: Amy E. TAPPER, Cassandra CELATKA, Arthur Glenn ROMERO, John M. MCCALL, Toni CHANCELLOR, He ZHAO, Betina BIOLATTO, Jian-Xie CHEN, Elisabeth C.A. BROT, Peter C. MICHELS, Venkat K. CHARI, Ian C. COTTERILL
  • Patent number: 11173156
    Abstract: Forms of 6-(3-chloro-4-cyclopropoxyphenyl)pyrimidine-4-carboxylic acid (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the forms of Compound I and salts or co-crystals thereof.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: November 16, 2021
    Assignee: CHDI Foundation, Inc.
    Inventors: Leticia M. Toledo-Sherman, Celia Dominguez, Vinod Khetarpal, Travis Lee Houston, Stephan D. Parent, Jian-xie Chen, Charles H. Montgomery, Geetha Banda
  • Publication number: 20210139437
    Abstract: Provided in this disclosure are methods for the synthesis of substituted 2-arylcyclopropylamines and 2-heteroarylcyclopropylamines and related compounds. Also provided are methods for reduction of thioesters to aldehydes, and methods for reductive animation of cyclopropylamines.
    Type: Application
    Filed: August 16, 2017
    Publication date: May 13, 2021
    Inventors: Amy E. TAPPER, Cassandra CELATKA, Arthur Glenn ROMERO, John M. MCCALL, Toni CHANCELLOR, Jian-Xie CHEN, Xuemei CHEN, He ZHAO, Betina BIOLATTO, Elisabeth C.A. BROT, Zhihua LI, Xiaoming LIAO
  • Publication number: 20210122755
    Abstract: This invention is in the area of synthesizing pyrimidine-based compounds useful in the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.
    Type: Application
    Filed: December 14, 2020
    Publication date: April 29, 2021
    Applicant: G1 Therapeutics, Inc.
    Inventors: Alexander Smith, Hannah S. White, Francis Xavier Tavares, Sergiy Krasutsky, Jian-Xie Chen, Roberta L. Dorrow, Hua Zhong
  • Publication number: 20210056956
    Abstract: According to some embodiments, a multi-layer speech recognition transcript post processing system may include a data-driven, statistical layer associated with a trained automatic speech recognition model that selects an initial transcript. A rule-based layer may receive the initial transcript from the data-driven, statistical layer and execute at least one pre-determined rule to generate a first modified transcript. A machine learning approach layer may receive the first modified transcript from the rule-based layer and perform a neural model inference to create a second modified transcript. A human editor layer may receive the second modified transcript from the machine learning approach layer along with an adjustment from at least one human editor. The adjustment may create, in some embodiments, a final transcript that may be used to fine-tune the data-driven, statistical layer.
    Type: Application
    Filed: August 21, 2019
    Publication date: February 25, 2021
    Inventors: Dimitrios Basile DIMITRIADIS, Xie CHEN, Nanshan ZENG, Yu SHI, Liyang LU
  • Publication number: 20200397782
    Abstract: Forms of 6-(3-chloro-4-cyclopropoxyphenyl)pyrimidine-4-carboxylic acid (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the forms of Compound I and salts or co-crystals thereof.
    Type: Application
    Filed: June 10, 2020
    Publication date: December 24, 2020
    Inventors: Leticia M. Toledo-Sherman, Celia Dominguez, Vinod Khetarpal, Travis Lee Houston, Stephan D. Parent, Jian-xie Chen, Charlie Montgomery, Geetha Banda
  • Patent number: 10865210
    Abstract: This invention is in the area of synthesizing pyrimidine-based compounds useful in the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: December 15, 2020
    Assignee: G1 Therapeutics, Inc.
    Inventors: Alexander Smith, Hannah S. White, Francis Xavier Tavares, Sergiy Krasutsky, Jian-Xie Chen, Roberta L. Dorrow, Hua Zhong
  • Publication number: 20190135820
    Abstract: This invention is in the area of synthesizing pyrimidine-based compounds useful in the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.
    Type: Application
    Filed: December 21, 2018
    Publication date: May 9, 2019
    Applicant: G1 Therapeutics, Inc.
    Inventors: Alexander Smith, Hannah S. White, francis Xavier Tavares, Sergiy Krasutsky, Jian-Xie Chen, Roberta L. Dorrow, Hua Zhong
  • Patent number: 10179774
    Abstract: Methods for preparing chirally purified substituted 4,5,6,7-tetrahydro-benzothiazole diamines such as, for example, (6R)2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole and purifying a dominant enantiomer of substituted 4,5,6,7-tetrahydro-benzothiazole diamines from entantiomerically enriched mixtures of substituted 4,5,6,7-tetrahydro-benzothiazole diamines are provided herein.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: January 15, 2019
    Assignee: Knopp Biosciences LLC
    Inventors: Prasad Raje, Rajendrakumar Reddy Gadikota, Jian-Xie Chen, Olga V. Lapina, John M. McCall