Patents by Inventor Xie Chen
Xie Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12020694Abstract: The computing system trains an end-to-end (E2E) automatic speech recognition (ASR) model, using a transformer-transducer-based deep neural network that comprises a transformer encoder network and a transducer predictor network. The E2E ASR model is trained to have one or more adjustable hyperparameters that are configured to dynamically adjust an efficiency or a performance of the E2E ASR model when the E2E ASR model is deployed onto a device or executed by the device, by identifying one or more conditions of the device associated with computational power of the device and setting at least one of the one or more adjustable hyperparameters based on one or more conditions of the device.Type: GrantFiled: June 8, 2023Date of Patent: June 25, 2024Assignee: Microsoft Technology Licensing, LLCInventors: Yu Wu, Jinyu Li, Shujie Liu, Xie Chen, Chengyi Wang
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Publication number: 20230317063Abstract: The computing system trains an end-to-end (E2E) automatic speech recognition (ASR) model, using a transformer-transducer-based deep neural network that comprises a transformer encoder network and a transducer predictor network. The E2E ASR model is trained to have one or more adjustable hyperparameters that are configured to dynamically adjust an efficiency or a performance of the E2E ASR model when the E2E ASR model is deployed onto a device or executed by the device, by identifying one or more conditions of the device associated with computational power of the device and setting at least one of the one or more adjustable hyperparameters based on one or more conditions of the device.Type: ApplicationFiled: June 8, 2023Publication date: October 5, 2023Inventors: Yu WU, Jinyu LI, Shujie LIU, Xie CHEN, Chengyi WANG
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Patent number: 11715462Abstract: A computing system is configured to generate a transformer-transducer-based deep neural network. The transformer-transducer-based deep neural network comprises a transformer encoder network and a transducer predictor network. The transformer encoder network has a plurality of layers, each of which includes a multi-head attention network sublayer and a feed-forward network sublayer. The computing system trains an end-to-end (E2E) automatic speech recognition (ASR) model, using the transformer-transducer-based deep neural network. The E2E ASR model has one or more adjustable hyperparameters that are configured to dynamically adjust an efficiency or a performance of E2E ASR model when the E2E ASR model is deployed onto a device or executed by the device.Type: GrantFiled: April 29, 2021Date of Patent: August 1, 2023Assignee: Microsoft Technology Licensing, LLCInventors: Yu Wu, Jinyu Li, Shujie Liu, Xie Chen, Chengyi Wang
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Patent number: 11629150Abstract: This invention is in the area of synthesizing pyrimidine-based compounds useful in the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.Type: GrantFiled: December 14, 2020Date of Patent: April 18, 2023Assignee: G1 Therapeutics, Inc.Inventors: Alexander Smith, Hannah S. White, Francis Xavier Tavares, Sergiy Krasutsky, Jian-Xie Chen, Roberta L. Dorrow, Hua Zhong
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Publication number: 20230104647Abstract: Provided in this disclosure are methods for the synthesis of substituted 2-arylcyclopropylamines and 2-heteroarylcyclopropylamines and related compounds. Also provided are methods for reduction of thioesters to aldehydes, and methods for reductive amination of cyclopropylamines.Type: ApplicationFiled: June 15, 2022Publication date: April 6, 2023Inventors: Amy E. TAPPER, Cassandra CELATKA, Arthur Glenn ROMERO, John M. MCCALL, Toni CHANCELLOR, Jian-Xie CHEN, Xuemei CHEN, He ZHAO, Betina BIOLATTO, Elisabeth C.A. BROT, Zhihua LI, Xiaoming LIAO
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Patent number: 11527238Abstract: A computer device is provided that includes one or more processors configured to receive an end-to-end (E2E) model that has been trained for automatic speech recognition with training data from a source-domain, and receive an external language model that has been trained with training data from a target-domain. The one or more processors are configured to perform an inference of the probability of an output token sequence given a sequence of input speech features. Performing the inference includes computing an E2E model score, computing an external language model score, and computing an estimated internal language model score for the E2E model. The estimated internal language model score is computed by removing a contribution of an intrinsic acoustic model. The processor is further configured to compute an integrated score based at least on E2E model score, the external language model score, and the estimated internal language model score.Type: GrantFiled: January 21, 2021Date of Patent: December 13, 2022Assignee: Microsoft Technology Licensing, LLCInventors: Zhong Meng, Sarangarajan Parthasarathy, Xie Sun, Yashesh Gaur, Naoyuki Kanda, Liang Lu, Xie Chen, Rui Zhao, Jinyu Li, Yifan Gong
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Publication number: 20220351718Abstract: A computing system is configured to generate a transformer-transducer-based deep neural network. The transformer-transducer-based deep neural network comprises a transformer encoder network and a transducer predictor network. The transformer encoder network has a plurality of layers, each of which includes a multi-head attention network sublayer and a feed-forward network sublayer. The computing system trains an end-to-end (E2E) automatic speech recognition (ASR) model, using the transformer-transducer-based deep neural network. The E2E ASR model has one or more adjustable hyperparameters that are configured to dynamically adjust an efficiency or a performance of E2E ASR model when the E2E ASR model is deployed onto a device or executed by the device.Type: ApplicationFiled: April 29, 2021Publication date: November 3, 2022Inventors: Yu WU, Jinyu LI, Shujie LIU, Xie CHEN, Chengyi WANG
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Patent number: 11390590Abstract: Provided in this disclosure are methods for the synthesis of substituted 2-arylcyclopropylamines and 2-heteroarylcyclopropylamines and related compounds. Also provided are methods for reduction of thioesters to aldehydes, and methods for reductive animation of cyclopropylamines.Type: GrantFiled: August 16, 2017Date of Patent: July 19, 2022Assignee: Imago Biosciences, Inc.Inventors: Amy E. Tapper, Cassandra Celatka, Arthur Glenn Romero, John M. McCall, Toni Chancellor, Jian-Xie Chen, Xuemei Chen, He Zhao, Betina Biolatto, Elisabeth C. A. Brot, Zhihua Li, Xiaoming Liao
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Publication number: 20220139380Abstract: A computer device is provided that includes one or more processors configured to receive an end-to-end (E2E) model that has been trained for automatic speech recognition with training data from a source-domain, and receive an external language model that has been trained with training data from a target-domain. The one or more processors are configured to perform an inference of the probability of an output token sequence given a sequence of input speech features. Performing the inference includes computing an E2E model score, computing an external language model score, and computing an estimated internal language model score for the E2E model. The estimated internal language model score is computed by removing a contribution of an intrinsic acoustic model. The processor is further configured to compute an integrated score based at least on E2E model score, the external language model score, and the estimated internal language model score.Type: ApplicationFiled: January 21, 2021Publication date: May 5, 2022Applicant: Microsoft Technology Licensing, LLCInventors: Zhong MENG, Sarangarajan PARTHASARATHY, Xie SUN, Yashesh GAUR, Naoyuki KANDA, Liang LU, Xie CHEN, Rui ZHAO, Jinyu LI, Yifan GONG
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Patent number: 11295172Abstract: Method of detecting objects in non-perspective images starts by generating an arrangement of tiles based on a field of view of a non-perspective camera lens, a predetermined size of the tiles, and a predetermined maximum object radius. The arrangement of the tiles includes the minimum number of tiles to cover the field of view. A non-perspective image is then captured using the non-perspective camera lens. The non-perspective image may be a still image frame or a video. Using the tiles, a plurality of images are generated, respectively, and at least a portion of a first object is detected in one or more images. The first object is generated using the one or more images that include the at least the portion of the first object, and the first object is displayed on a display interface. Other embodiments are described herein.Type: GrantFiled: May 21, 2019Date of Patent: April 5, 2022Assignee: Snap Inc.Inventors: Kevin Xie Chen, Shree K. Nayar
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Patent number: 11257484Abstract: According to some embodiments, a multi-layer speech recognition transcript post processing system may include a data-driven, statistical layer associated with a trained automatic speech recognition model that selects an initial transcript. A rule-based layer may receive the initial transcript from the data-driven, statistical layer and execute at least one pre-determined rule to generate a first modified transcript. A machine learning approach layer may receive the first modified transcript from the rule-based layer and perform a neural model inference to create a second modified transcript. A human editor layer may receive the second modified transcript from the machine learning approach layer along with an adjustment from at least one human editor. The adjustment may create, in some embodiments, a final transcript that may be used to fine-tune the data-driven, statistical layer.Type: GrantFiled: August 21, 2019Date of Patent: February 22, 2022Assignee: Microsoft Technology Licensing, LLCInventors: Dimitrios Basile Dimitriadis, Xie Chen, Nanshan Zeng, Yu Shi, Liyang Lu
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Publication number: 20220025424Abstract: The present disclosure relates to compositions and methods for producing stereoisomerically pure aminocyclopropanes.Type: ApplicationFiled: August 16, 2017Publication date: January 27, 2022Inventors: Amy E. TAPPER, Cassandra CELATKA, Arthur Glenn ROMERO, John M. MCCALL, Toni CHANCELLOR, He ZHAO, Betina BIOLATTO, Jian-Xie CHEN, Elisabeth C.A. BROT, Peter C. MICHELS, Venkat K. CHARI, Ian C. COTTERILL
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Patent number: 11173156Abstract: Forms of 6-(3-chloro-4-cyclopropoxyphenyl)pyrimidine-4-carboxylic acid (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the forms of Compound I and salts or co-crystals thereof.Type: GrantFiled: June 10, 2020Date of Patent: November 16, 2021Assignee: CHDI Foundation, Inc.Inventors: Leticia M. Toledo-Sherman, Celia Dominguez, Vinod Khetarpal, Travis Lee Houston, Stephan D. Parent, Jian-xie Chen, Charles H. Montgomery, Geetha Banda
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Publication number: 20210139437Abstract: Provided in this disclosure are methods for the synthesis of substituted 2-arylcyclopropylamines and 2-heteroarylcyclopropylamines and related compounds. Also provided are methods for reduction of thioesters to aldehydes, and methods for reductive animation of cyclopropylamines.Type: ApplicationFiled: August 16, 2017Publication date: May 13, 2021Inventors: Amy E. TAPPER, Cassandra CELATKA, Arthur Glenn ROMERO, John M. MCCALL, Toni CHANCELLOR, Jian-Xie CHEN, Xuemei CHEN, He ZHAO, Betina BIOLATTO, Elisabeth C.A. BROT, Zhihua LI, Xiaoming LIAO
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Publication number: 20210122755Abstract: This invention is in the area of synthesizing pyrimidine-based compounds useful in the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.Type: ApplicationFiled: December 14, 2020Publication date: April 29, 2021Applicant: G1 Therapeutics, Inc.Inventors: Alexander Smith, Hannah S. White, Francis Xavier Tavares, Sergiy Krasutsky, Jian-Xie Chen, Roberta L. Dorrow, Hua Zhong
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Publication number: 20210056956Abstract: According to some embodiments, a multi-layer speech recognition transcript post processing system may include a data-driven, statistical layer associated with a trained automatic speech recognition model that selects an initial transcript. A rule-based layer may receive the initial transcript from the data-driven, statistical layer and execute at least one pre-determined rule to generate a first modified transcript. A machine learning approach layer may receive the first modified transcript from the rule-based layer and perform a neural model inference to create a second modified transcript. A human editor layer may receive the second modified transcript from the machine learning approach layer along with an adjustment from at least one human editor. The adjustment may create, in some embodiments, a final transcript that may be used to fine-tune the data-driven, statistical layer.Type: ApplicationFiled: August 21, 2019Publication date: February 25, 2021Inventors: Dimitrios Basile DIMITRIADIS, Xie CHEN, Nanshan ZENG, Yu SHI, Liyang LU
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Publication number: 20200397782Abstract: Forms of 6-(3-chloro-4-cyclopropoxyphenyl)pyrimidine-4-carboxylic acid (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the forms of Compound I and salts or co-crystals thereof.Type: ApplicationFiled: June 10, 2020Publication date: December 24, 2020Inventors: Leticia M. Toledo-Sherman, Celia Dominguez, Vinod Khetarpal, Travis Lee Houston, Stephan D. Parent, Jian-xie Chen, Charlie Montgomery, Geetha Banda
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Patent number: 10865210Abstract: This invention is in the area of synthesizing pyrimidine-based compounds useful in the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.Type: GrantFiled: December 21, 2018Date of Patent: December 15, 2020Assignee: G1 Therapeutics, Inc.Inventors: Alexander Smith, Hannah S. White, Francis Xavier Tavares, Sergiy Krasutsky, Jian-Xie Chen, Roberta L. Dorrow, Hua Zhong
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Publication number: 20190135820Abstract: This invention is in the area of synthesizing pyrimidine-based compounds useful in the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.Type: ApplicationFiled: December 21, 2018Publication date: May 9, 2019Applicant: G1 Therapeutics, Inc.Inventors: Alexander Smith, Hannah S. White, francis Xavier Tavares, Sergiy Krasutsky, Jian-Xie Chen, Roberta L. Dorrow, Hua Zhong
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Patent number: 10179774Abstract: Methods for preparing chirally purified substituted 4,5,6,7-tetrahydro-benzothiazole diamines such as, for example, (6R)2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole and purifying a dominant enantiomer of substituted 4,5,6,7-tetrahydro-benzothiazole diamines from entantiomerically enriched mixtures of substituted 4,5,6,7-tetrahydro-benzothiazole diamines are provided herein.Type: GrantFiled: December 5, 2016Date of Patent: January 15, 2019Assignee: Knopp Biosciences LLCInventors: Prasad Raje, Rajendrakumar Reddy Gadikota, Jian-Xie Chen, Olga V. Lapina, John M. McCall