Patents by Inventor Xijun Yan

Xijun Yan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180042893
    Abstract: A pharmaceutical composition for treating non-alcoholic fatty liver diseases consists of a silybin-phospholipid complex preparation and Pu'er tea/tea product according to a weight ratio of 0.5-2.5:0.3-10, wherein the silybin-phospholipid complex capsule preparation and the Pu'er teat/tea product are separately packaged.
    Type: Application
    Filed: March 22, 2016
    Publication date: February 15, 2018
    Inventors: Naifeng WU, Xijun YAN, He SUN, Kaijirig YAN, Yonghong ZHU, Shunnan ZHANG, Xiaolin BAI, Yi HE, Xiaohni MA, Ting LI
  • Publication number: 20180042892
    Abstract: Disclosed is a pharmaceutical composition containing silibinin, which is prepared from the following bulk drugs by weight ratio: 8.75-60 parts of silibinin, 15-65 parts of phospholipid, and 25-200 parts of Pu'er tea extract. The drug has the function of treating non-alcoholic fatty liver.
    Type: Application
    Filed: March 22, 2016
    Publication date: February 15, 2018
    Inventors: Naifeng WU, Xijun YAN, He SUN, Kaijing YAN, Yonghong ZHU, Shunnan ZHANG, Xiaolin BAI, Yi HE, Xiaohui MA, Ting LI, Lei LI
  • Patent number: 9795648
    Abstract: A pharmaceutical composition for treating headache, prepared from eleven Chinese herbal medicines: Chinese angelica root, ligusticum chuanxiong, radix paeoniae lactiflorae, prepared rhizome of rehmannia, uncaria tomentosa, leatherleaf milletia, prunella vulgaris, sicklesenna seed, pearl shell, corydalis tuber, and asarum, and a proper amount of adjuvant materials. A preparation method of the pharmaceutical composition, and uses thereof in the preparation of drugs for treating various headaches, traumatic cranial nerve syndrome, dizziness and vertigo, vexation and irritability, insomnia and dreaminess.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: October 24, 2017
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Shunnan Zhang, Jianhui Yang, Yan Liu, Xingyun Shao, Song Gao, Lina Dong, Xiaolin Bai, Yan Sun, Bo Xu, Yongfeng Zheng, Lijun Fan
  • Publication number: 20170157156
    Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.
    Type: Application
    Filed: July 11, 2014
    Publication date: June 8, 2017
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Zhengliang Ye, Shunnan Zhang, Lihong Zhou, Wensheng Zhang, Hai'ou Dong
  • Publication number: 20160184249
    Abstract: A traditional Chinese medicine composition and preparation thereof for treating cardiovascular diseases is provided. The traditional Chinese medicine composition consists of: by weight percentage, phenolic acid derivatives 30%˜80%, tanshinones 2%˜10% and saponins 15%˜60%.
    Type: Application
    Filed: August 28, 2014
    Publication date: June 30, 2016
    Applicant: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Shunnan Zhang, Ping Li, Zhengliang Ye, Lihong Zhou, Lianwen Qi, Fenglian Zhang, Minchao Qi, Zhexuan Yang, Wei Sun, Jing Yu, Hua Yang, Peng Liu, Xiaohui Ma, Hai'ou Dong, Wensheng Zhang, Lanlan Zhang, Chenming Li
  • Publication number: 20160175336
    Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.
    Type: Application
    Filed: July 11, 2014
    Publication date: June 23, 2016
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Zhengliang Ye, Shunnan Zhang, Lihong Zhou, Wensheng Zhang, Hai'ou Dong
  • Publication number: 20160151293
    Abstract: The present invention relates to a preparation method for a traditional Chinese medicine drop pill and a traditional Chinese medicine micro drop pill prepared by using the method, and in particular, the present invention relates to a micro drop pill preparation method with high drug-loading capacity, simple preparation process and high production rate and a micro drop pill prepared by using the method. Specially, The drop pill preparation method used comprises the following steps: (1) material melting step: heat melting a medicine and a drop pill matrix to obtain a molten medicine liquid; (2) dropping step: delivering the molten medicine liquid to a dripper, and acquiring medicine drops of the molten medicine liquid by means of vibration dropping; and, (3) condensation step: cooling the medicine drops with a cooling gas to obtain micro drop pills.
    Type: Application
    Filed: July 11, 2014
    Publication date: June 2, 2016
    Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Xiaobing Sun, Shunnan Zhang, Zhengliang Ye, Hai'ou Dong, Hongbo Zhang, Wensheng Zhang, Lihong Zhou, Chenming Li, Cong Chen, Xiaofeng Liu, Shiqing Wang, Changsheng Rong, Yongfeng Zheng, Lijun Fan
  • Publication number: 20160143976
    Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.
    Type: Application
    Filed: July 11, 2014
    Publication date: May 26, 2016
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Zhengliang Ye, Shunnan Zhang, Lihong Zhou, Wensheng Zhang, Hai'ou Dong, Yongfeng Zheng, Lijun Fan
  • Patent number: 9211310
    Abstract: The present invention relates to a use of Chinese medicine composition in preparation of medicine for secondary prevention of myocardial infarction. Said Chinese medicine composition is prepared from a formula comprising the crude drugs by the following weight percentages: Radix Astragali 22.2%˜66.8%, Radix Salviae Miltiorrhizae 11.6%˜33.4%, Radix Notoginseng 2.5%˜13.5%, and Lignum Dalbergiae Odoriferae 14.5%˜44.3%.
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: December 15, 2015
    Assignee: TASLY PHARMACEUTICAL GROUP CO., LTD
    Inventors: Boli Zhang, Hongcai Shang, Chen Yao, Baoyan Liu, Weiliang Weng, Yuxia Zhao, Guohua Dai, Xiumei Gao, Ming Ren, Junhua Zhang, Hongbo Cao, Jingyuan Mao, Xuejun Hu, Zhisheng Jin, Junping Zhang, Yiyu Cheng, Xijun Yan, Jiazhen Qu, Hui Wang, Hongjuan Xu, Wenke Zheng
  • Publication number: 20150352168
    Abstract: A pharmaceutical composition for treating headache, prepared from eleven Chinese herbal medicines: Chinese angelica root, ligusticum chuanxiong, radix paeoniae lactiflorae, prepared rhizome of rehmannia, uncaria tomentosa, leatherleaf milletia, prunella vulgaris, sicklesenna seed, pearl shell, corydalis tuber, and asarum, and a proper amount of adjuvant materials. A preparation method of the pharmaceutical composition, and uses thereof in the preparation of drugs for treating various headaches, traumatic cranial nerve syndrome, dizziness and vertigo, vexation and irritability, insomnia and dreaminess.
    Type: Application
    Filed: December 19, 2013
    Publication date: December 10, 2015
    Applicant: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xijun YAN, Naifeng WU, Shunnan ZHANG, Jianhui YANG, Yan LIU, Xingyun SHAO, Song GAO, Lina DONG, Xiaolin BAI, Yan SUN, Bo XU, Yongfeng ZHENG, Lijun FAN
  • Patent number: 9072745
    Abstract: Provided is the use of a Salvia Miltiorrhiza composition in preparing drugs for secondary prevention of coronary heart disease, and particularly the use of the Salvia Miltiorrhiza composition in preparing drugs for secondary prevention of stable angina type coronary heart disease and the reduction of serious vascular events.
    Type: Grant
    Filed: August 8, 2011
    Date of Patent: July 7, 2015
    Assignee: TASLY PHARMACEUTICAL GROUP CO., LTD
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, He Sun, Zhixin Guo, Guoguang Zhu, Weiwei Liu, Libin Zhao, Ruizhi Luo
  • Patent number: 8883228
    Abstract: This invention provides a composition for heart disease comprising extracts from raw herbs of 80.0-97.0% Radix Salviae Miltorrhizae, 1.0-19.0% Panax Notoginseng and 0.1-1.0% Borneol and its active ingredients. This invention also provides a method for preparing said composition and the active ingredients of the composition. Finally, this invention provides various uses of said compositions and the active ingredients.
    Type: Grant
    Filed: February 16, 2010
    Date of Patent: November 11, 2014
    Assignee: Tasly Pharmaceutical Group Co. Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Zhixin Guo, Zhengliang Ye, Yan Liu
  • Patent number: 8747913
    Abstract: A pharmaceutical composition consisting of Radix Polygoni Multiflori extract, Salviae Miltiorrhizae extract, Fructus Crataegi extract and Radix Notoginseng extract is described, wherein the composition optionally contains a pharmaceutical carrier. Processes for producing the composition and methods for treating and/or preventing hyperlipidemia, treating and/or preventing fatty liver and lowering blood lipid level by administration of the pharmaceutical composition are also disclosed.
    Type: Grant
    Filed: December 5, 2005
    Date of Patent: June 10, 2014
    Assignee: Tasly Pharmaceutical Group Co., Ltd
    Inventors: Xijun Yan, Boli Zhang, Zhixin Guo, Guoguang Zhu, Zhengliang Ye, Feng Wei, Ruizhi Luo
  • Publication number: 20130209590
    Abstract: The present invention relates to a use of Chinese medicine composition in preparation of medicine for secondary prevention of myocardial infarction. Said Chinese medicine composition is prepared from a formula comprising the crude drugs by the following weight percentages: Radix Astragali 22.2%˜66.8%, Radix Salviae Miltiorrhizae 11.6%˜33.4%, Radix Notoginseng 2.5%˜13.5%, and Lignum Dalbergiae Odoriferae 14.5%˜44.3%.
    Type: Application
    Filed: June 28, 2011
    Publication date: August 15, 2013
    Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Boli Zhang, Hongcai Shang, Chen Yao, Baoyan Liu, Weiliang Weng, Yuxia Zhao, Guohua Dai, Xiumei Gao, Ming Ren, Junhua Zhang, Hongbo Cao, Jingyuan Mao, Xuejun Hu, Zhisheng Jin, Junping Zhang, Yiyu Cheng, Xijun Yan, Jiazhen Qu, Hui Wang, Hongjuan Xu, Wenke Zheng
  • Publication number: 20130196005
    Abstract: Provided is the use of a Salvia Miltiorrhiza composition in preparing drugs for secondary prevention of coronary heart disease, and particularly the use of the Salvia Miltiorrhiza composition in preparing drugs for secondary prevention of stable angina type coronary heart disease and the reduction of serious vascular events.
    Type: Application
    Filed: August 8, 2011
    Publication date: August 1, 2013
    Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Xijun Yan, Naifeng Wu, Kai Yan, He Sun, Zhixin Guo, Guoguang Zhu, Weiwei Liu, Libin Zhao, Ruizhi Luo
  • Patent number: 8486464
    Abstract: This invention provides compositions comprising extracts of Radix Salviae Miltiorrhizae, Radix Notoginseng and Borneol. Said compositions comprise notoginsenoside R1 and ginsenoside Rg1 which are active components for therapeutic applications. This invention also provides a method of preparation of the said compositions and a method of identification and determination of the amount of individual effective components of said compositions. Finally, this invention provides various uses of the compositions.
    Type: Grant
    Filed: July 31, 2002
    Date of Patent: July 16, 2013
    Assignee: Tasly Pharmaceutical Group Co. Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Zhixin Guo, Zhengliang Ye, Yan Liu
  • Publication number: 20110195136
    Abstract: The present invention relates to a drop pill for treating coronary heart disease, comprising an active pharmaceutical ingredient (API), a matrix adjuvant, a plastifying adjuvant, propylene glycol and water. the API is prepared from Radix salvia miltiorrhira, Panax notoginseng and Borneol; the matrix adjuvant is erythritol; the plastifying adjuvant is one or more selected from the group consisting of polyethylene glycols, xylitol, lactitol, mannitol, glycerine, soluble amylum, gelatin, methyl cellulose, sodium carboxymethycellulose (CMC-Na), hydroxypropyl methylcellulose (HPMC), arabic gum, alginic acid, dextrin, cyclodextrin (CD), citrate, glycerol acetate, dibutyl sebacate, refined coconut oil and castor oil; Wherein, relative to the total weight of the drop pill, the API is 1˜40 wt %, the plastifying adjuvant 0˜10 wt %, the propylene glycol 1˜10 wt %, the water 0˜10 wt % and the balance is the matrix adjuvant.
    Type: Application
    Filed: September 30, 2009
    Publication date: August 11, 2011
    Inventors: Jianming Chen, Xijun Yan, Yonghong Zhu, Baoan Gao, Shunnan Zhang, Haiou Dong, Jizhong Zhang, Wei Li, Xinjiang Yan, Ying Zhao
  • Publication number: 20100136146
    Abstract: This invention provides a composition for heart disease comprising extracts from raw herbs of 80.0-97.0% Radix Salviae Miltorrhizae, 1.0-19.0% Panax Notoginseng and 0.1-1.0% Borneol and its active ingredients. This invention also provides a method for preparing said composition and the active ingredients of the composition. Finally, this invention provides various uses of said compositions and the active ingredients.
    Type: Application
    Filed: February 16, 2010
    Publication date: June 3, 2010
    Inventors: Xijun YAN, Naifeng WU, Zhixin GUO, Zhengliang YE, Yan LIU
  • Publication number: 20090291154
    Abstract: The present invention discloses a pharmaceutical composition comprising Polygonum multiflorum Thunb, which comprises Polygonum multiflorum Thunb, Fructus Crataegi, Salvia miltiorrhiza Bunge and Radix Notoginseng. If needed, the pharmaceutical composition may comprise the pharmaceutically acceptable carriers. The weight ratio of Polygonum multiflorum Thunb, Salvia miltiorrhiza Bunge, Fructus Crataegi and Radix Notoginseng in the present composition is as follows: 10 to 20 parts of Polygonum multiflorum Thunb, 5 to 15 parts of Salvia miltiorrhiza Bunge, 10 to 20 parts of Fructus Crataegi and 1 to 10 parts of Radix Notoginseng. Also, the present invention discloses the methods for preparing the composition, including directly pulverizing the medicines into powder to produce the composition or preparing the medicines into the extracts and then make the extracts into drugs.
    Type: Application
    Filed: December 5, 2005
    Publication date: November 26, 2009
    Applicant: Tianjin Tasly Pharmaceutical Co., Ltd.
    Inventors: Xijun Yan, Boli Zhang, Zhixin Guo, Guoguang Zhu, Zhengliang Ye, Feng Wei, Ruizhi Luo
  • Publication number: 20080305189
    Abstract: The present invention relates to the treatment of aspirin resistant cardio-cerebrovascular diseases using RSM (RSM), its extract and composition comprising any or both of them, especially the formulation Dan Shen Drop Pills (Drop Pills of RSM).
    Type: Application
    Filed: August 20, 2008
    Publication date: December 11, 2008
    Applicant: Tianjin Tasly Pharmaceutical Co., Ltd.
    Inventors: Xijun YAN, Naifeng WU, Zhengliang YE, Xu LI, Zhixin GUO, Na ZHAO