Abstract: A deep-sea crawling robot and a crawling method thereof are provided. The deep-sea crawling robot includes a crawling robot body and a countertop, wherein a top of the crawling robot body is fixedly connected to the countertop, left and right sides of a bottom of the crawling robot body are respectively provided with crawler belts, and left and right sides of the countertop are respectively provided with weight-increasing auxiliary crawling mechanisms; and an outer plate is fixedly connected to a front side or back side of the countertop, a multifunctional propelling mechanism is arranged on the outer plate, and a rapid dewatering mechanism is arranged in a chamber of the countertop. The deep-sea crawling robot can not only accelerate the propulsion and crawling speed when it is on the seabed but also further enhance its stability during the crawling process on the seabed.

Abstract: A bottom touching assisting device suitable for deep-sea submersibles and an implementation method thereof are provided. Four support columns are arranged within a mounting box body at a bottom of a deep-sea submersible, the support columns and the mounting box body are connected in a sliding manner through sliders, and the support column is sleeved with a threaded sleeve in a threaded connection manner. In conjunction with a drive component and a pressing mechanism, smooth vertical movement of the support column is achieved when the threaded sleeve rotates. This allows a bottom end of the support column to extend from the mounting box body.

Abstract: Peptide vaccine that is a mixture of different peptide species, where each species has a number of fixed amino acid residues and a number of randomized residues. The fixed resides are the same amino acid residues at the corresponding positions in each species of the mixture while the randomized residues are randomly any available candidate amino acids chosen by design. The degree of randomization may be also been chosen according to the design under a particular situation. This type of peptide vaccines have shown to be able to induce highly specific antibodies against epitopes that are otherwise difficult to induce antibodies in vitro, for example the GPG triplet in the V3 of HIV-1 gp120.

Abstract: The present invention relates to the field of applied immunotechnology and medicine. More specifically, it relates to DNA motif vaccine design, glyco-DNA motif vaccine design, and immunogen design for producing antibodies against an epitope of arbitrary sequences or polysaccharide epitope, particularly those epitopes against which it is otherwise very difficult to induce antibodies, such as those of HIV-1. The present invention also relates to immunogen design to induce robust cellular and humoral immunity.

Abstract: The present invention relates to the field of applied immunotechnology and medicine. More specifically, it relates to DNA motif vaccine design, glyco-DNA motif vaccine design, and immunogen design for producing antibodies against an epitope of arbitrary sequences or polysaccharide epitope, particularly those epitopes against which it is otherwise very difficult to induce antibodies, such as those of HIV-1. The present invention also relates to immunogen design to induce robust cellular and humoral immunity.

Abstract: Peptide vaccine that is a mixture of different peptide species, where each species has a number of fixed amino acid residues and a number of randomized residues. The fixed resides are the same amino acid residues at the corresponding positions in each species of the mixture while the randomized residues are randomly any available candidate amino acids chosen by design. The degree of randomization may be also been chosen according to the design under a particular situation. This type of peptide vaccines have shown to be able to induce highly specific antibodies against epitopes that are otherwise difficult to induce antibodies in vitro, for example the GPG triplet in the V3 of HIV-1 gp120.