Patents by Inventor XIN (ALEX) ZHANG

XIN (ALEX) ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250134907
    Abstract: Disclosed is a compound of formula (I), in which R1, R2, R3, R4, R5, X1, X2, X3, X4, and X5 are described herein. The small molecule compounds of formula (I) activate the functional activity of relaxin family peptide receptor 2 (RXFP2), thereby providing therapeutic treatments for a variety of disorders, such as a bone disorder, hypogonadism, cryptorchidism, polycystic ovary syndrome, cancer, infertility, or an ocular wound.
    Type: Application
    Filed: January 31, 2023
    Publication date: May 1, 2025
    Applicants: The United States of America,as represented by the Secretary,Department of Health and Human Services, The Florida International University Board of Trustees
    Inventors: Juan J. Marugan, Noel T. Southall, Marc Ferrer, Mark J. Henderson, Kenneth J. Wilson, Alexander I. Agoulnik, Courtney B. Myhr, Maria Esteban-Lopez, Elena Barnaeva, Xin Hu, Wenjuan Ye, Irina Agoulnik
  • Patent number: 12285911
    Abstract: A 3D printing method for an impact-resistant gradient complex part containing a hollow ceramic sphere complex, wherein the method includes the following steps: 1) designing the size and shape of the part as well as an internal layered structure; 2) providing a raw material, wherein the raw material contains a high polymer, a curing agent and hollow ceramic spheres; and 3) providing the raw material with a certain thickness according to a design, then, curing the raw material by using a heat source to form a high polymer layer containing the hollow ceramic spheres, and repeatedly printing the high polymer layer according to the design until the high polymer layer reaches the designed thickness to form the impact-resistant gradient complex part.
    Type: Grant
    Filed: December 30, 2022
    Date of Patent: April 29, 2025
    Assignee: XI'AN JIAOTONG UNIVERSITY
    Inventors: ChunMing Niu, MeiPing Li, QiPing He, Jun Li, Fan Jiang, ZhiHui Li, Xin Ji, ZhaoHai Meng, ShunXiang Gong
  • Patent number: 12287198
    Abstract: A heterodyne laser interferometer and a measurement method based on an integrated dual polarization beam-splitting assembly is provided. Technical points: The first polarization beam splitter and the second polarization beam splitter of the integrated dual polarization beam-splitting assembly are arranged in parallel. The first polarization beam splitter is attached with a first polarizer, a third polarizer, and a first quarter-wave plate; The second polarization beam splitter is attached with a second polarizer, a fourth polarizer, and a second quarter-wave plate; The output optical path of the first quarter-wave plate and the second quarter-wave plate is equipped with target mirrors, while the output optical path of the third quarter-wave plate and the fourth quarter-wave plate is equipped with photodetectors. The assembly and adjustment of the present invention is more flexible and reduce the processing difficulty and processing error.
    Type: Grant
    Filed: March 4, 2024
    Date of Patent: April 29, 2025
    Assignee: HARBIN INSTITUTE OF TECHNOLOGY
    Inventors: Haijin Fu, Xiaobo Su, Liang Yu, Pengcheng Hu, Xizheng Liu, Xin Yang
  • Patent number: 12287555
    Abstract: A photosensitive device and a display panel are provided. The photosensitive device includes a substrate and a photosensitive functional layer. The photosensitive functional layer includes a thin film transistor layer and a quantum dot layer. The quantum dot layer is configured to emit an excitation light under an excitation of an external light. A photo-generated current efficiency of the photosensitive device can be improved, and stability and versatility of the photosensitive device can also be improved.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: April 29, 2025
    Assignee: Shenzhen China Star Optoelectronics Semiconductor Display Technology Co., Ltd.
    Inventors: Haijun Wang, Xin Zhang, Miao Jiang, Jiangbo Yao
  • Patent number: 12289978
    Abstract: A display substrate includes at least two barrier layers in a peripheral area of the display substrate. The at least two barrier layers includes a first barrier layer forming an enclosure; and a third barrier layer on a side of the first barrier layer closer to a display area. The third barrier layer includes one or more discontinuous portions.
    Type: Grant
    Filed: August 17, 2021
    Date of Patent: April 29, 2025
    Assignees: Chengdu BOE Optoelectronics Technology Co., Ltd., BOE Technology Group Co., Ltd.
    Inventors: Lu Bai, Yang Zhou, Xin Zhang, Junxiu Dai, Yi Zhang, Tinghua Shang, Bo Zhang, Yao Huang, Song Liu
  • Patent number: 12288845
    Abstract: A solid electrolyte material having a general chemical formula of Li2+xM2+xM?1?xS6, where M is at least one of Al, Ga or In, M? is at least one of Si or Ge, and 0<x?0.5. The solid electrolyte material according to the application is simple in composition, contains no phosphorus sensitive to water, and has good Li+ conductivity at the same time.
    Type: Grant
    Filed: March 30, 2022
    Date of Patent: April 29, 2025
    Assignee: Ningde Amperex Technology Limited
    Inventors: Molin Zhou, Feng Gu, Xin Jiang, Leimin Xu
  • Patent number: 12286677
    Abstract: The disclosure provides methods of identifying a human subject as a candidate for treating or inhibiting a liver disease by inhibiting HSD17B13. The disclosure also provides methods of treating a subject who is PNPLA3 Ile148Met+ by administering an inhibitor of HSD17B13. The disclosure also provides method of detecting a PNPLA3 Ile148Met variant and functional HSD17B13 in a subject. The disclosure also provides method of identifying a subject having a protective effect against liver disease. The disclosure also provides inhibitors of HSD17B13 for use in the treatment of a liver disease.
    Type: Grant
    Filed: May 30, 2023
    Date of Patent: April 29, 2025
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Yurong Xin, Jesper Gromada, Xiping Cheng, Frederick Dewey, Tanya Teslovich Dostal, Claudia Schurmann, Aris Baras, Noura Abul-Husn
  • Patent number: 12287304
    Abstract: Disclosed are a flexible pH sensor and detection system, belonging to the technical field of sensors. A material that does not react with electrolyte is mixed with metals to print an anode substrate, and one-step synthesis of a metal ions doped polyaniline composite material is realized through an electrochemical method. The doping amount of metal ions in polyaniline is changed by controlling metal content; due to addition of the metals, the conductivity of the anode substrate is improved, which is conducive to the deposition of polyaniline; such one-step method for preparing the polyaniline composite material is simpler, low in cost, and pollution-free; and compared with pure polyaniline, the sensitivity is further improved. According to the solution, this material is applied to the pH sensor for the first time, achieving a wide pH detection range (2-12) and high bending stability.
    Type: Grant
    Filed: July 15, 2024
    Date of Patent: April 29, 2025
    Assignee: Jiangnan University
    Inventors: Jie Zhang, Fenglong Shang, Fei Li, Siqi Nan, Xin Meng, Baobing Zhang, Tianwei Zhang, Xuhui Wang
  • Patent number: 12287156
    Abstract: Provided is a partition plate used in a ventilator that supplies air and exhausts air at the same time. The partition plate includes: a first layer including a first porous substrate having a plurality of first pores, the first layer having a first pinhole formed by at least some of the first pores; a second layer stacked on the first layer and including a second porous substrate having a plurality of second pores, the second layer having a second pinhole formed by at least some of the second pores, the second pinhole being located at a position different from a position facing the first pinhole; and a third layer stacked on the second layer and made of a water-insoluble moisture-permeable resin.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: April 29, 2025
    Assignee: MITSUBISHI ELECTRIC CORPORATION
    Inventors: Tasuku Izutani, Shinya Tokizaki, Takumi Oho, Hajime Sotokawa, Xin Wang
  • Patent number: 12289932
    Abstract: An ejector pin sliding on membrane-based device and method for mass transfer of mini light-emitting diodes (Mini-LEDs) are provided. The device includes a gantry transverse beam. The gantry transverse beam is provided with an ejector pin base, and the ejector pin base is configured to move along the gantry transverse beam. The ejector pin base is fixedly provided with a vision camera and an ejector pin. A blue membrane is horizontally provided at a side of the gantry transverse beam close to the ejector pin, and is spaced from the gantry beam. A surface of a side of the blue membrane away from the gantry transverse beam is adhesively provided with a plurality of Mini-LED chips arranged evenly. A transfer substrate is horizontally provided at a side of the blue membrane close to the plurality of Mini-LED chips, and is spaced from the blue membrane.
    Type: Grant
    Filed: July 11, 2024
    Date of Patent: April 29, 2025
    Assignee: Guangdong University of Technology
    Inventors: Yun Chen, Yanhui Chen, Li Ma, Hao Zhang, Jintao Chen, Maoxiang Hou, Xin Chen
  • Patent number: 12286471
    Abstract: Disclosed herein are Complement factor H (CFH) inhibitors, such as anti-CFH antibodies and small molecules, and methods of using said inhibitors.
    Type: Grant
    Filed: January 3, 2024
    Date of Patent: April 29, 2025
    Assignee: Duke University
    Inventors: Edward F. Patz, Jr., Michael J. Campa, Elizabeth Gottlin, Barton F. Haynes, Hua-Xin Liao, M. Anthony Moody
  • Patent number: 12286354
    Abstract: A method for manufacturing a humidity alarm device based on laser-induced graphene is performed as follows. Carbon-based films are coated with a hydroxide ion-containing solution and processed by a laser device to generate hydrophilic graphene layers. The hydrophilic graphene layers are peeled off from the carbon-based films, wetted, and respectively wrapped around shaping rods varying in diameter. The wrapped rods are heated and shaped by a drying oven to obtain curled graphene switches. Each curled graphene switch is connected in series with an alarm lamp to form an alarm component. The alarm components are connected in parallel, and then connected to a positive terminal and a negative terminal of a power supply to form the humidity alarm device.
    Type: Grant
    Filed: December 16, 2024
    Date of Patent: April 29, 2025
    Assignee: Guangdong University of Technology
    Inventors: Yun Chen, Bin Xie, Yuanhui Guo, Hao Zhang, Maoxiang Hou, Li Ma, Xin Chen
  • Patent number: 12288086
    Abstract: An application interface layout method includes that a developer sets a layout container having an adaptive layout capability in a layout file of an application, where the adaptive layout capability includes at least one of an extension capability, a proportion capability, an equalization capability, a wrapping capability, a hiding capability, a stretching capability, or a scaling capability. In this way, when running the application, an electronic device arranges, based on a screen parameter of the electronic device and the adaptive layout capability of the layout container in the layout file, a size and a location of a child view in the layout container on a display interface.
    Type: Grant
    Filed: March 28, 2023
    Date of Patent: April 29, 2025
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Wei Zhong, Yang Li, Zhang Gao, Longjiao Xin, Qichao Yang, Bo Tang, Tong Jiao, Xiaoxiao Chen, Jun Zhu, Letian Liu, Duoxian Li
  • Patent number: 12287384
    Abstract: A radio-frequency power output device includes a cooling plate, a temperature detection module, and a control module. The cooling plate is provided with a first circuit board and a second circuit board respectively on two opposite sides thereof, and the first circuit board and the second circuit board are provided with a first radio-frequency power amplification circuit and a second radio-frequency power amplification circuit, respectively. The temperature detection module is used to obtain the temperature of the first circuit board and the temperature of the second circuit board. The control module controls, based on the temperature of the first circuit board, the first radio-frequency power amplification circuit to output a radio-frequency power signal at a target temperature, and controls, based on the temperature of the second circuit board, the second radio-frequency power amplification circuit to output a radio-frequency power signal at the target temperature.
    Type: Grant
    Filed: July 10, 2023
    Date of Patent: April 29, 2025
    Assignee: GE Precision Healthcare LLC
    Inventors: Yu Liu, Xin Xie, Kai Wang, Tingting Song, Chunlai Xiao, Dongliang Yang, Jianye Ning
  • Patent number: 12289578
    Abstract: A bone conduction microphone is provided. The bone conduction microphone may include a laminated structure formed by a vibration unit and an acoustic transducer unit. The bone conduction microphone may include a base structure configured to carry the laminated structure. At least one side of the laminated structure may be physically connected to the base structure. The base structure may vibrate based on an external vibration signal. The vibration unit may be deformed in response to the vibration of the base structure. The acoustic transducer unit may generate an electrical signal based on the deformation of the vibration unit. The bone conduction microphone may include at least one damping structural layer. The at least one damping structural layer may be arranged on an upper surface, a lower surface, and/or an interior of the laminated structure, and the at least one damping layer may be connected to the base structure.
    Type: Grant
    Filed: July 3, 2024
    Date of Patent: April 29, 2025
    Assignee: SHENZHEN SHOKZ CO., LTD.
    Inventors: Wenbing Zhou, Yongshuai Yuan, Wenjun Deng, Xin Qi, Fengyun Liao
  • Patent number: 12287602
    Abstract: A developing cartridge includes: a cartridge body for accommodating developers; a driving part at a first end in a first direction; a developing roller rotatable about a rotation axis extending along the first direction and positioned at a third end in a second direction; a storage medium for storing information; an electrical contact surface electrically connected to the storage medium and fixed relative to the cartridge body, and a lifting element configured to lift up the cartridge body in the third direction. The electrical contact surface is positioned at the first end in the first direction and is farther away from the developing roller relative to the driving part. The lifting element is farther away from the developing roller in the second direction away from the driving part.
    Type: Grant
    Filed: August 2, 2024
    Date of Patent: April 29, 2025
    Assignee: Zhuhai Ninestar Information Technology Co., Ltd
    Inventors: Hao Yang, Chen Cheng, Xin Lv, Hailong Ma, Wenjie Zhao, Leizhi Kuang, Jiming Zhou, Xinyu Wu, Changbiao Wang, Qingrui Zhu, Haoli Huang, Junyu Tao, Tiansheng Peng, Yuanyuan Sun, Caixia Chen
  • Patent number: 12289266
    Abstract: The present disclosure relates to reference signal resource configuration methods and apparatus. In one example reference signal resource configuration method, a terminal receives sounding reference signal (SRS) resource configuration information from a base station. In response to determining that at least two SRS resources indicated by the SRS resource configuration information are located on a same orthogonal frequency division multiplexing (OFDM) symbol, the terminal maps one of the at least two SRS resources to the OFDM symbol.
    Type: Grant
    Filed: August 4, 2022
    Date of Patent: April 29, 2025
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Xin Gao, Yongping Zhang, Tie Li, Su Huang
  • Patent number: 12286884
    Abstract: A rotary digging drill includes three disk drills arranged in ascending order of diameter, each with a cavity therein. The disk drill includes two circular ring seats arranged side by side, multiple toothed digging buckets disposed at peripheries of the two circular ring seats, and ring gear racks respectively disposed on inner sides of the two circular ring seats. Adjacent ones of the disk drills have the toothed digging buckets facing opposite directions, and the disk drills all rotate in a direction facing a large opening, enabling adjacent two of the three disk drills to rotate in opposite directions. The rotary digging drill further includes three disk drill supports that match the three disk drills in quantity and are configured to support and drive the three disk drills.
    Type: Grant
    Filed: April 19, 2023
    Date of Patent: April 29, 2025
    Assignees: WUHAN CONSTRUCTION ENGINEERING GROUP CO., LTD., INSTITUTE OF ROCK AND SOIL MECHANICS, CHINESE ACADEMY OF SCIENCES
    Inventors: Shuai Wang, Aixun Wang, Qingshan Meng, Mingzhao Wang, Wenxiang Li, Tong Lu, Ming You, Xin Li, Hui Wang, Zhizhen Wu, Keyang Wu, Chen Liu, Chen Qian, Li Wang, Wei Yang, Yunjie Dong, Shenghao Li
  • Patent number: 12285329
    Abstract: A method and system provide an ophthalmic device. The ophthalmic device includes an ophthalmic lens having anterior surface, a posterior surface and at least one diffractive structure including a plurality of zones. The at least one diffractive structure is for at least one of the anterior surface and the posterior surface. Each zone includes at least one echelette having a least one step height. The step height(s) are individually optimized for each zone. To compensate chromatic aberration of eye from distance to a range of vision, a greater than 2? phase step height may be employed and the step height(s) folded by a phase, which is an integer multiple of two multiplied by ?. Hence chromatic aberration of eye may be compensated to improve vision from distance to near.
    Type: Grant
    Filed: February 26, 2024
    Date of Patent: April 29, 2025
    Assignee: Alcon Inc.
    Inventors: Xin Hong, Shinwook Lee
  • Patent number: D1072738
    Type: Grant
    Filed: February 15, 2023
    Date of Patent: April 29, 2025
    Inventor: Xin Chen