Abstract: Provided are a compound as represented by formula (I), and a pharmaceutically acceptable salt, tautomer, mesomer, racemate, stereoisomer, metabolite, metabolic precursor, or drug precursor thereof, and application thereof as a protein regulator, in particular a GSPT1 protein regulator, and a preparation method.

Abstract: A radio-frequency power amplification module for a magnetic resonance system and an imaging method are provided. The radio-frequency power amplification module includes: a power synthesizer, a main amplifier, and an auxiliary amplifier, output ends of the main amplifier and the auxiliary amplifier being both connected to a power synthesis unit; and a controller. The controller is configured to output a control signal according to a required radio-frequency transmission parameter or a scan parameter corresponding to the radio-frequency transmission parameter, so as to adjust a control parameter of the auxiliary amplifier. The radio-frequency power amplification module has high efficiency.

Abstract: Embodiments of this application provide a data transmission method, apparatus, and device. In the data transmission method, a first apparatus obtains a first link quality packet message that includes link quality information and indication information. The indication information is used to indicate that the link quality information is buffered. The first apparatus sends the first link quality packet message to a second apparatus, where the first link quality packet message is used by the second apparatus to perform network optimization based on the first link quality packet message. The data transmission method disclosed herein improves network optimization accuracy.

Abstract: Disclosed is a semiconductor laser with a substrate mode suppression layer, comprising a substrate, a first limiting layer, a first waveguide layer, an active layer, a second waveguide layer, an electron blocking layer, and a second limiting layer sequentially stacked from bottom to top. A Si/C concentration ratio of an element Si to an element C of the substrate mode suppression layer?that of the first sub-limiting layer?that of the second sub-limiting layer. An In/Al concentration ratio of an element In to an element Al of the substrate mode suppression layer?that of the first sub-limiting layer?that of the second sub-limiting layer. An H/C concentration ratio of an element H to an element C of the substrate mode suppression layer?that of the second sub-limiting layer?that of the first sub-limiting layer.

Abstract: The present disclosure provides a compound having a novel structure as a PRMT5 inhibitor, a method for preparing the compound, and use thereof in the treatment of a disease mediated by a PRMT5 inhibitor. Experiments have shown that these compounds have a strong inhibitory effect on PRMT5, and can be used as promising candidate compounds for treatment of diseases mediated by PRMT5 inhibitors. In addition, a specific synthetic method is developed in the present disclosure, which has a simple process and convenient operation, and is beneficial to industrial mass production and application.

Abstract: Disclosed is a semiconductor laser with a substrate mode suppression layer, comprising a substrate, a first limiting layer, a first waveguide layer, an active layer, a second waveguide layer, an electron blocking layer, and a second limiting layer sequentially stacked from bottom to top. A Si/C concentration ratio of an element Si to an element C of the substrate mode suppression layer?that of the first sub-limiting layer?that of the second sub-limiting layer. An In/Al concentration ratio of an element In to an element Al of the substrate mode suppression layer?that of the first sub-limiting layer?that of the second sub-limiting layer. An H/C concentration ratio of an element H to an element C of the substrate mode suppression layer?that of the second sub-limiting layer?that of the first sub-limiting layer.

Abstract: A magnetic resonance system, a transmission apparatus, and a transmission method is provided. The transmission method includes: generating and outputting a pulse signal by a signal output unit, amplifying the pulse signal by a radio-frequency power amplifier, and transferring, by an impedance matching circuit, the signal amplified by the radio-frequency power amplifier to a transmit coil of the magnetic resonance system; and determining a first phase among a plurality of adjustable phases that enables a performance indicator of the radio-frequency power amplifier to meet a first condition, and adjusting an output impedance of the impedance matching circuit at least according to the first phase.

Abstract: A nitrogen-containing heterocyclic compound, a preparation method therefor, and an application thereof in medicines. Specifically, the present disclosure relates to a nitrogen-containing heterocyclic compound as represented by general formula (IM), a preparation method therefor, a pharmaceutical composition comprising the compound, a use of the pharmaceutical composition serving as a therapeutic agent, in particular as a PARP1 inhibitor, and a use of the pharmaceutical composition in the preparation of a drug for treating and/or preventing cancer.

Abstract: An electronic ink screen and a display apparatus. The electronic ink screen includes at least the following which are stacked: a first conductive substrate, an ink display layer and a second conductive substrate. The ink display layer is located between the first conductive substrate and the second conductive substrate, and the second conductive substrate is located above the first conductive substrate. The ink display layer has a plurality of ink accommodating cavities that are mutually independent. A plurality of ink particles that have a same color are provided in the ink accommodating cavity. The ink particles are used for displaying a first color. The electronic ink screen further includes a function layer. The function layer is configured to display a second color. The function layer is located at a side that is of the ink display layer and that faces away from the second conductive substrate.

Abstract: A photovoltaic array fault diagnosis method based on composite information is provided. The method includes: collecting and preprocessing composite information data of photovoltaic array working state, including image data and text data; using the image data of photovoltaic array working state to train a pre-established fault classification model of deep convolutional neural network, to thereby obtain an image fault classification model; using the text data of photovoltaic array working state to train a pre-established fault classification model based on a support vector machine, to thereby obtain a text fault classification model; fusing the image fault classification model and the text fault classification model by logistic regression algorithm to obtain a fusion model, and training the fusion model using the composite information data of photovoltaic array working state to thereby obtain the photovoltaic array fault diagnosis model.

Abstract: A farmland reference crop evapotranspiration prediction method based on uncertainty of meteorological factors, includes: S1. acquiring a set number of groups of weather forecast data of a prediction region within a preset time period; S2. inputting each group of weather forecast data into a Bayesian probability forecast system to obtain corrected weather forecast data; and S3. inputting each group of the corrected weather forecast data into a trained RBF neural network, and predicting to obtain a farmland reference crop evapotranspiration. In the present invention, the Bayesian probability forecast system is configured to correct the weather forecast data and eliminate uncertainty of weather forecast data to obtain the accurate reference crop evapotranspiration forecasted by the RBF neural network using these data.

Abstract: A compound, as represented by formula I, as a TLR7 agonist, a method for preparing the compound, and the use of the compound in treating diseases mediated by the TLR7 agonist are provided. Studies on the activity of a human-derived receptor, a TLR7 agonist, show that compounds have a strong agonistic effect on the human-derived receptor, TLR7, and can be used as a foreground compound for treating diseases mediated by the TLR7 agonist.

Abstract: A fluorescent compound for acid detection is strongly emissive in the solid state and can aggregate in the presence of an acid. As such, a fluorescent intensity emitted from the compound can be enhanced from an original intensity level in the presence of an acid. The fluorescent compound can emit an enhanced fluorescent intensity in the presence of an ultra-low acid concentration, for example, a concentration of at least about 10?20 M.

Abstract: A data partition storage system is provided. The system includes: a data analysis device, configured to determine, according to a data feature of target data comprised in a database, a heat level corresponding to the target data; and a database kernel, deployed on a target device different from the data analysis device to form the database, and configured to: acquire the heat level corresponding to the target data transmitted by the data analysis device; and store the target data in a storage area corresponding to the heat level.

Abstract: A method of fabricating an optical lens disclosed herein includes forming a layer of a flat lens structure on a front surface of a substrate, depositing a protective metal layer on the layer of the flat lens structure and on a back surface of the substrate, wherein the protective layer includes chromium, gold, titanium, or nickel, wherein the back surface is located opposite to and away from the front surface having the layer of the flat lens structure, irradiating the protective metal layer at the front surface with a laser to form a channel (i) through the protective metal layer, (ii) through the layer of the flat lens structure and (iii) in the substrate, removing the protective metal layer at the front surface and the back surface of the substrate, and separating the layer of the flat lens structure from the substrate to obtain the optical lens, wherein the channel has a depth defined by a thickness of the substrate remaining at the channel after irradiating the protective metal layer at the front surface

Abstract: Embodiments of this application provide a data transmission method, apparatus, and device. The method includes: A first apparatus obtains a first link quality packet message, where the first link quality packet message includes link quality information and indication information, and the indication information is used to indicate that the link quality information is buffered; and the first apparatus sends the first link quality packet message to a second apparatus, where the first link quality packet message is used by the second apparatus to perform network optimization based on the first link quality packet message. This improves accuracy of network optimization.

Abstract: Systems and methods of reconstructing photoacoustic imaging data corresponding to a brain of a subject through a skull of a subject utilizing a reconstruction method that incorporates a spatial model of one or more acoustic properties of the brain and skull of the subject derived from an adjunct imaging dataset.

Abstract: Systems and methods of reconstructing photoacoustic imaging data corresponding to a brain of a subject through a skull of a subject utilizing a reconstruction method that incorporates a spatial model of one or more acoustic properties of the brain and skull of the subject derived from an adjunct imaging dataset.

Abstract: A tank for substrate cleaning, a tank heating apparatus, a tank heating method and a substrate cleaning apparatus are provided. The substrate cleaning tank includes a tank body, a hot waste gas recycle tube, a heater and a heat exchange tube. The hot waste gas recycle tube is used to receive a hot waste gas in a hot waste gas discharge tube of a production line, the heater and the heat exchange tube are used to heat a fluid in the tank body, and the heat exchange tube is communicated with the hot waste gas recycle tube. The hot waste gas is effectively utilized, the power consumption is reduced, the production cost is saved, and the discharge of the hot waste gas is reduced.

Abstract: A fluorescent compound for acid detection is strongly emissive in the solid state and can aggregate in the presence of an acid. As such, a fluorescent intensity emitted from the compound can be enhanced from an original intensity level in the presence of an acid. The fluorescent compound can emit an enhanced fluorescent intensity in the presence of an ultra-low acid concentration, for example, a concentration of at least about 10?20 M.