Abstract: A method and system for predicting regional gas consumption, and a device and a cloud platform. The future gas consumption of all gas users in an entire region is predicted according to a user-specified region and date; all networked gas users in the region are extracted during a prediction process by using spatial address matching technology; and then, by means of classifying the users and sampling the users in combination with statistics, representative sample users are extracted from all the users for respective prediction, thereby reducing the computation amount and computing resource consumption, which are required for model prediction. The method and system is mounted on a cloud platform, and the cloud platform receives, by means of Internet of Things technology, gas flow data that is uploaded by gas flow metering devices of all networked gas users, and also provides an interface for interacting with the users for the outside.

Abstract: Provided are a method for driving a light-emitting substrate, a driving circuit and a display apparatus. The light-emitting substrate includes: at least one control region, which includes a plurality of light-emitting sub-regions, the light-emitting sub-region includes a plurality of light-emitting elements which are connected in series and/or in parallel; each light-emitting sub-regions includes a first signal end and a second signal end, in a same control region, the first signal ends of all the light-emitting sub-regions are electrically connected with each other, and the second signal ends of the different light-emitting sub-regions are independent of each other; the method includes: loading a first signal to the first signal ends in the control region; and loading second signals to the second signal ends of each of the plurality of the light-emitting sub-regions in the control region when a first duration is delayed after the first signal is provided.

Abstract: The present disclosure belongs to the technical field of drug delivery and biomimetic structures inducing cell proliferation and differentiation, and in particular relates to a micro-nano medical stent for directional, quantitative and timed controlled release of drug and a preparation method thereof. The micro-nano medical stent provided by the present disclosure is composed of an ordered fiber structure electrospun as a skeleton layer and a disordered fiber structure electrospun as an ECM layer that can both load drugs. The micro-nano medical stent can achieve directional, quantitative and timed release of drugs.

Abstract: An ejector pin sliding on membrane-based device and method for mass transfer of mini light-emitting diodes (Mini-LEDs) are provided. The device includes a gantry transverse beam. The gantry transverse beam is provided with an ejector pin base, and the ejector pin base is configured to move along the gantry transverse beam. The ejector pin base is fixedly provided with a vision camera and an ejector pin. A blue membrane is horizontally provided at a side of the gantry transverse beam close to the ejector pin, and is spaced from the gantry beam. A surface of a side of the blue membrane away from the gantry transverse beam is adhesively provided with a plurality of Mini-LED chips arranged evenly. A transfer substrate is horizontally provided at a side of the blue membrane close to the plurality of Mini-LED chips, and is spaced from the blue membrane.

Abstract: A method for manufacturing a humidity alarm device based on laser-induced graphene is performed as follows. Carbon-based films are coated with a hydroxide ion-containing solution and processed by a laser device to generate hydrophilic graphene layers. The hydrophilic graphene layers are peeled off from the carbon-based films, wetted, and respectively wrapped around shaping rods varying in diameter. The wrapped rods are heated and shaped by a drying oven to obtain curled graphene switches. Each curled graphene switch is connected in series with an alarm lamp to form an alarm component. The alarm components are connected in parallel, and then connected to a positive terminal and a negative terminal of a power supply to form the humidity alarm device.

Abstract: Provided herein are methods of removing carbon dioxide from an aqueous stream or gaseous stream by: contacting the gaseous stream comprising carbon dioxide, when present, with an aqueous solution comprising ions capable of forming an insoluble carbonate salt; contacting the aqueous solution comprising carbon dioxide with an electroactive mesh that induces its alkalinization thereby forcing the precipitation of a carbonate solid from the solution and thereby the removal of dissolved inorganic carbon by electrolysis; and removing the precipitated carbonate solids from the solution, or the surface of the mesh where they may deposit. Also provided herein are flow-through electrolytic reactors comprising an intake device in fluid connection with a rotating cylinder comprising an electroactive mesh, and a scraping device and/or liquid-spray based device for separating a solid from the mesh surface.

Abstract: An optical fiber including: (1) a first outer cladding region including a no-slope portion establishing a 0% baseline (?0); (2) a core region surrounded by the first outer cladding region, the core region including (i) an outer radius (r1) from 4.0 ?m to 6.5 ?m and (ii) a maximum relative refractive index (?1max) from 0.3% to 0.6%, the core region exhibiting an ? value of 5 or greater; and (3) a depressed index cladding region surrounding the core region and surrounded by the first outer cladding region, the depressed index cladding region including (i) an outer radius (r3) from 14 ?m to 28 ?m, (ii) a relative refractive index (?3) from ?0.45% to ?0.30%, and (iii) a trench volume (VT) from 65%-?m2 to 140%-?m2. The optical fiber exhibits lower LP01 bending loss than LP11 bending loss at operating wavelengths in the O- and C-bands.

Abstract: A system performs operations that include receiving, via first computing environment, a request to process text data using a first natural language processing (NLP) model. The operations further include accessing configuration data associated with the NLP model, where the configuration data generated using a domain specific language that supports a plurality of preprocessing modules in a plurality of programming languages. The operations also include selecting, based on the configuration data, one or more preprocessing modules of the plurality of preprocessing modules, generating, based on the configuration data, a preprocessing pipeline using the one or more preprocessing modules, and generating preprocessed text data by inputting the text data into the preprocessing pipeline. The preprocessed text data is provided to the first NLP model.

Abstract: The present application relates to treating and/or preventing breast cancer, including locally advanced or metastatic, ER+, HER2? breast cancer, in a subject in need of treatment, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt, enantiomer, stereoisomer, solvate, polymorph, isotopic derivative, or prodrug thereof, wherein R1, R2, R3, R4, m, and n are defined herein.

Abstract: The present disclosure provides a pillow. The pillow relates to the technical field of pillows. The pillow includes a pillow body. The pillow body is provided with a head support and a neck supporting end; the neck supporting end is arranged on an outer side of the head support; the neck supporting end is a convex plate extending outwards relative to the head support; a height range of the head support is 6 cm to 12 cm; and a height range of the neck supporting end is 6 cm to 12 cm. By the adoption of the above technical solutions, the neck supporting end is configured to carry the cervical vertebra of the user, so that when people sleep on the pillow, the cervical vertebra can maintain a natural physiological curve, making people sleep more comfortably.

Abstract: Techniques for determining trajectories for a plurality of wells while avoiding collision between wells are presented. The techniques can include determining a zone of uncertainty for individual wells of the plurality of wells, determining a minimum separation factor for individual wells of the plurality of wells, determining a gradient of a separation factor for at least one pair of wells of the plurality of pairs of wells, updating a nudge position for at least one well, and providing nudge positions for the individual wells of the plurality of wells.

Abstract: The present invention relates to a ligand, a method for preparing same, and a use thereof. The ligand has a structure represented by formula (I) or formula (II), wherein R1, R2, R3, and R4 are all linear structures with a glycosyl group at a terminal end; X and Y are both Y-shaped backbone structures connected with other chemical groups; and X1, X2, and Y are all Y-shaped backbone structures connected with other chemical groups.

Abstract: A method for manufacturing a humidity alarm device based on laser-induced graphene is performed as follows. Carbon-based films are coated with a hydroxide ion-containing solution and processed by a laser device to generate hydrophilic graphene layers. The hydrophilic graphene layers are peeled off from the carbon-based films, wetted, and respectively wrapped around shaping rods varying in diameter. The wrapped rods are heated and shaped by a drying oven to obtain curled graphene switches. Each curled graphene switch is connected in series with an alarm lamp to form an alarm component. The alarm components are connected in parallel, and then connected to a positive terminal and a negative terminal of a power supply to form the humidity alarm device.

Abstract: A pixel driving circuit and a display apparatus. The pixel driving circuit includes a pulse amplitude modulation circuit and a pulse width modulation circuit electrically connected to each other. The pulse amplitude modulation circuit is electrically connected to a light-emitting element to provide a drive current thereto and is configured to control an amplitude of the drive current. The pulse width modulation circuit is configured to control a pulse width of the drive current. The pulse amplitude modulation circuit includes a light-emitting branch connected to the light-emitting element, which includes a first driving transistor and at least one switching transistor. The at least one transistor is a double-gate double-channel transistor.

Abstract: The present invention relates to bifunctional compounds, which find utility as modulators of targeted ubiquitination, especially inhibitors of a variety of polypeptides and other proteins which are degraded and/or otherwise inhibited by bifunctional compounds according to the present invention. In particular, the present invention is directed to compounds, which contain on one end a VHL ligand which binds to the ubiquitin ligase and on the other end a moiety which binds a target protein such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of that protein. The present invention exhibits a broad range of pharmacological activities associated with compounds according to the present invention, consistent with the degradation/inhibition of targeted polypeptides.

Abstract: A method including transmitting an intensity-modulated light through a mode conditioner to generate a mode-conditioned intensity-modulated light in one or a plurality of launch conditions and transmitting the mode-conditioned intensity-modulated light through a multimode optical fiber under test (FUT) to excite a plurality of modes of the FUT. The method further includes converting the mode-conditioned intensity-modulated light transmitted through the FUT into an electrical signal, measuring, based on the electrical signal, a complex transfer function CTF(f) of the FUT, and obtaining an output pulse based on the measured complex transfer function CTF(f) from one or a plurality of launch conditions and an assumed input pulse using the equation: Pout (t)=?1(CTF(f)*(Pin(t))). Wherein, Pout (t) is the output pulse, ?1(CTF(f)*(Pin(t))) is the inverse Fourier transform of the function CTF(f)*(Pin (t)), and (Pin(t)) is the Fourier transform of the assumed input pulse.

Abstract: A device for mass transfer of Mini-LEDs based on array water jet-based ejection, including a planar motion platform, a vision camera, an array water jet-type ejection unit, a Z-axis motion platform, a blue membrane, an operation platform and a transfer substrate. The vision camera and the array water jet-type ejection unit are provided on a side of the planar motion platform. The array water jet-type ejection unit includes a water jet channel and a through-hole array. The Z-axis motion platform is provided at a side of the planar motion platform near the vision camera, and is configured for placement of the blue membrane. Multiple Mini-LED chips are bonded to the blue membrane. The operation platform is spacedly provided at a side of the Z-axis motion platform away from the planar motion platform.