Abstract: Systems and methods relating to placement of an ultrasound transducer for a procedure. In a non-limiting embodiment, a 3D environment including images of a body region of a patient, as well as images including a first virtual representation of an ablation needle at a first location and a second virtual representation of an ultrasound transducer at a second location is rendered on a display device. A determination may be made as to whether the first and second virtual representations collide at a first collision point. If so, at least one parameter associated with an orientation and/or position of the second virtual representation may be adjusted. A determination may then be made as to whether or not the first and second virtual representations still collide and, in response to determining that there is no collision, position data indicating the location of the second virtual representation after the adjustment, is stored.

Abstract: A system for providing visual three dimensional assistance to a user during a medical procedure involving a soft organ. The system and method provide visual assistance to a user during a medical procedure involving a soft organ. The system and method utilize a processor for generating an image of the soft organ, a surgical instrument tracker for tracking a surgical instrument during the medical procedure, and a display in communication with the processor and the surgical instrument tracker for visually displaying in three dimensions, the image of the soft organ and the surgical instrument in relation to the soft organ.

Abstract: Provided is a method for the high expression of a recombinant human serum albumin, characterized in comprising the step of co-expressing: (a) a human serum albumin gene, and (b) one or more rHSA expression promoting factor genes in a yeast host cell.

Abstract: The present teaching relates to surgical procedure assistance. In one example, a first image of an organ having a lesion is obtained prior to a surgical procedure. Information related to a pose of a surgical instrument at a first location with respect to the lesion is received from a sensor coupled with the surgical instrument. A visual environment having the lesion and the surgical instrument rendered therein is generated based on the first image and the information received from the sensor. A second image of the organ is obtained when the surgical instrument is moved to a second location with respect to the lesion during the surgical procedure. The second image captures the lesion and the surgical instrument. The pose of the surgical instrument and the lesion rendered in the visual environment are adjusted based, at least in part, on the second image.

Abstract: The present teaching relates to surgical procedure assistance. In one example, a first set of positions of a plurality of sensors are obtained in an image captured prior to a surgical procedure. The plurality of sensors are coupled with a patient's body. One or more second sets of positions of the plurality of sensors are obtained based on information from a tracking device associated with the plurality of sensors. The one or more second sets of positions change in accordance with movement of the patient's body. One or more similarity measures are calculated between the first set of positions and each of the one or more second sets of positions of the plurality of sensors. A timing at which the surgical procedure initiates is determined based on the one or more similarity measures.

Abstract: The present teaching relates to surgical procedure assistance. In one example, a plurality of similarity measures are determined between a first set of positions and a plurality of second sets of positions, respectively. The first set of positions is obtained with respect to a plurality of sensors coupled with a patient in an image captured prior to a surgical procedure. The plurality of second sets of positions are obtained from the plurality of sensors and change in accordance with movement of the patient. A target lesion is segmented in the image captured prior to the surgical procedure to obtain a lesion display object. The lesion display object is duplicated to generate a plurality of lesion display objects. The plurality of lesion display objects are presented on a display screen so that a distance between the plurality of lesion display objects changes in accordance with the plurality of the similarity measures.

Abstract: Systems and methods relating to placement of an ultrasound transducer for a procedure. In a non-limiting embodiment, a 3D environment including images of a body region of a patient, as well as images including a first virtual representation of an ablation needle at a first location and a second virtual representation of an ultrasound transducer at a second location is rendered on a display device. A determination may be made as to whether the first and second virtual representations collide at a first collision point. If so, at least one parameter associated with an orientation and/or position of the second virtual representation may be adjusted. A determination may then be made as to whether or not the first and second virtual representations still collide and, in response to determining that there is no collision, position data indicating the location of the second virtual representation after the adjustment, is stored.

Abstract: The present teaching relates to surgical procedure assistance. In one example, a plurality of similarity measures are determined between a first set of positions and a plurality of second sets of positions, respectively. The first set of positions is obtained with respect to a plurality of sensors coupled with a patient in an image captured prior to a surgical procedure. The plurality of second sets of positions are obtained from the plurality of sensors and change in accordance with movement of the patient. A target lesion is segmented in the image captured prior to the surgical procedure to obtain a lesion display object. The lesion display object is duplicated to generate a plurality of lesion display objects. The plurality of lesion display objects are presented on a display screen so that a distance between the plurality of lesion display objects changes in accordance with the plurality of the similarity measures.

Abstract: The present teaching relates to surgical procedure assistance. In one example, a first set of positions of a plurality of sensors are obtained in an image captured prior to a surgical procedure. The plurality of sensors are coupled with a patient's body. One or more second sets of positions of the plurality of sensors are obtained based on information from a tracking device associated with the plurality of sensors. The one or more second sets of positions change in accordance with movement of the patient's body. One or more similarity measures are calculated between the first set of positions and each of the one or more second sets of positions of the plurality of sensors. A timing at which the surgical procedure initiates is determined based on the one or more similarity measures.

Abstract: The present teaching relates to surgical procedure assistance. In one example, a first image of an organ having a lesion is obtained prior to a surgical procedure. Information related to a pose of a surgical instrument at a first location with respect to the lesion is received from a sensor coupled with the surgical instrument. A visual environment having the lesion and the surgical instrument rendered therein is generated based on the first image and the information received from the sensor. A second image of the organ is obtained when the surgical instrument is moved to a second location with respect to the lesion during the surgical procedure. The second image captures the lesion and the surgical instrument. The pose of the surgical instrument and the lesion rendered in the visual environment are adjusted based, at least in part, on the second image.

Abstract: A system for providing visual three dimensional assistance to a user during a medical procedure involving a soft organ. The system and method provide visual assistance to a user during a medical procedure involving a soft organ. The system and method utilize a processor for generating an image of the soft organ, a surgical instrument tracker for tracking a surgical instrument during the medical procedure, and a display in communication with the processor and the surgical instrument tracker for visually displaying in three dimensions, the image of the soft organ and the surgical instrument in relation to the soft organ.