Abstract: A functional peptide modified magnetic composite nanobead, and a method and an application thereof for detecting ?-secretase (BACE1) and screening its inhibitors are provided. The chemical composition of the magnetic composite nanobead is: ferroferric oxide (Fe3O4) nanoclusters used as magnetic cores, the surface of the magnetic cores coated with a silica shell, the surface of the shell connected with an ethylene diamine tetraacetic acid (EDTA) modification layer, and Co2+ or Ni2+ ions chelated on the EDTA layer, and the Cy5 fluorescein labeled functional peptide coated on the surface of magnetic composite nanobead by the interaction between Co2+ or Ni2+ ions and hexahistidine-tag.

Abstract: A deep learning-based method for recognizing continuous shovel loading positions in an autonomous loader includes: acquiring laser point cloud data representing surface topography of a stockpile, and processing the laser point cloud data to obtain shovel-loading region features of the stockpile; constructing a model of an actuating mechanism for a loader, performing simulation force analysis on the model of the actuating mechanism and the shovel-loading region features of the stockpile, to obtain shovel-loading position features of the stockpile; analyzing and evaluating the shovel-loading position features of the stockpile to obtain an optimal shovel-loading position feature of the stockpile; and constructing a detection model, acquiring an image of the stockpile to be identified simultaneously, inputting the image of the stockpile to be identified into the detection model for processing, and detecting and adjusting a shovel-loading position of the loader based on the image processing results and the optimal

Abstract: Provided is a packaging structure for packaging an organic light emitting diode, which consists only of two layers, namely an organic barrier layer and an inorganic barrier layer. The organic barrier layer is formed by a photocurable composition, and in parts by weight, the photocurable composition includes 5-20 parts by weight of a silicon-based photocurable monofunctional monomer, 30-50 parts by weight of a silicon-based photocurable bifunctional monomer, 20-60 parts by weight of a non-silicon-based photocurable monomer, and 1-10 parts by weight of a photoinitiator. The packaging structure of the present application has only two layers, meeting the development needs of an OLED device towards light weight, thin thickness, and low cost. Compared with the prior art, it can better suppress the erosion of moisture and/or oxygen on the OLED device, thus improving the reliability and service life of the OLED device.

Abstract: Provided are a method and a system for constructing an ocean significant wave height retrieval model of spaceborne GNSS-R under high sea conditions, acquiring modeling data, auxiliary data and verification data; extracting characteristic variable parameters and auxiliary variable parameter of modeling data, and matching that extracted variable parameter in time and space; carrying out data quality control and data set division on the variable parameters after time-space matching; using the divided data set to construct and train the WaveMambaFormer model, and using the SHAP explainer to calculate the feature importance and global interpretation, so as to enhance the explainability of the WaveMambaFormer model; the significant wave height data of ERA5, WaveWatch III and Jason-3 are used as reference data to evaluate the retrieval performance of WaveMambaFormer model.

Abstract: Provided are a high-flexibility ultraviolet curable ink and a packaging layer thereof. Raw materials of the ink at least includes in parts by weight: 50 to 90 parts of a light curable silicon-containing monomer, 10 to 40 parts of light curable non-silicon monomers, and 0.01 to 10 parts of a photoinitiator. By using the light curable silicon-containing monomer which do not contain an aromatic ring structure, a stress distribution effect can be achieved under the action of external force by utilizing the strong deformation capacity of an Si—O—Si chain segment of the light curable silicon-containing monomer, so that the plasma etching resistance of a packaging layer is improved, and compared with ultraviolet curable ink containing a benzene ring, the high-flexibility ultraviolet curable ink has higher flexibility and better anti-yellowing performance.

Abstract: The present application belongs to the technical field of ink compositions. Provided are photocurable ink composition, and preparation method and application thereof. The photocurable ink composition includes a photocurable monofunctional silicon-containing monomer A, a photocurable bifunctional silicon-containing monomer B, a photocurable non-silicon monomer C, and a photoinitiator D. The photocurable ink composition has a high photocuring rate and plasma etching resistance, and the number of free small molecules is reduced, such that emission of impurity gases is reduced. Furthermore, an organic layer formed through curing has excellent flexibility, such that the bendability of an Organic Light-Emitting Diode is ensured.

Abstract: Provided is a light adjusting packaging composition for an OLED, a packaging film and a preparation method therefor. The light adjusting packaging composition includes a photocurable glue composition and scattering particles. The scattering particles account for 1-10 wt % of the total weight of the light adjusting packaging composition, and a refractive index difference between the photocurable glue composition and the scattering particles is less than 0.2. Polysiloxane microspheres having an average particle size of 0.1-2 ?m are dispersed in the photocurable glue composition, and when the refractive index of the polysiloxane microspheres is less than the refractive index of the photocurable glue composition, a light adjusting packaging film having a light scattering function can be formed. The packaging film is suitable for a top-emitting OLED light-emitting device, such that the light deviation of the OLED caused by different observation angles is avoided, and the light diffusion effect is improved.

Abstract: The present invention discloses a progressive power grid planning evaluation method and system based on a combination assessment theory, and relates to the technical field of power grid assessment and optimization. The method includes: correcting a weight of an obtained index by using a combination weighting method; obtaining an assessed value based on a similarity theory assessment method; standardizing an index by dimensionless processing; and performing evaluation based on nonparametric regression. The present invention ensures objectivity and fairness of an assessment result and the efficiency and the accuracy of assessment are improved. The present invention may be adaptively adjusted, making the assessment result closer to reality.

Abstract: A real-time human posture tracking and calibration device and a system for tumor radiotherapy are provided, which may replace the traditional treatment bed of a linear accelerator. For tumor targets in areas such as the head and neck that do not move with respiration, the system tracks changes in the skin external contour and the static position of the tumor. For tumors in the chest and abdomen that are significantly affected by respiration, the system first tracks changes in the skin external contour and then compensates for the displacement of the tumor target moving with respiration.

Abstract: A real-time human posture tracking and calibration device and a system for tumor radiotherapy are provided, which may replace the traditional treatment bed of a linear accelerator. For tumor targets in areas such as the head and neck that do not move with respiration, the system tracks changes in the skin external contour and the static position of the tumor. For tumors in the chest and abdomen that are significantly affected by respiration, the system first tracks changes in the skin external contour and then compensates for the displacement of the tumor target moving with respiration.

Abstract: The present invention includes compositions and methods for retrieving tumor-related antibodies and antigens. In one aspect, the invention includes a method for Sequential Tumor-related Antibody and antigen Retrieving (STAR) which directly and efficiently identifies potent antibodies that can specifically bind to tumor-related antigens on the tumor cell surface. In another aspect, the invention includes a CAR comprising a nanobody, a transmembrane domain, and an intracellular domain, wherein the nanobody is retrieved by a STAR method. In another aspect, the invention includes a CAR T system that targets CD13 and treats acute myeloid leukemia. In another aspect, the invention includes a CAR T system and ADC that targets CDH17 and treats NETs and other types of tumors expressing this antigen, with tolerable toxicities.

Abstract: Disclosed are an energy efficiency testing device and method for an electric oven. The device includes a base, further including a clamping device and a correction device, a conveying device arranged on an inner wall surface of the base, an electric oven body arranged at a top of the conveying device, a testing platform fixedly mounted at a top of the base, a detection device fixedly mounted on a surface of the testing platform, and a display fixedly mounted at a top of the testing platform. The clamping device includes a support frame, a temperature sensor, an electric push rod, a push plate, an elastic telescopic rod, a connecting plate, and sponge blocks. The support frame is fixedly mounted at the top of the base, and the temperature sensor is fixedly mounted at a top of the support frame.

Abstract: Disclosed are an energy efficiency testing device and method for an electric oven. The device includes a base, further including a clamping device and a correction device, a conveying device arranged on an inner wall surface of the base, an electric oven body arranged at a top of the conveying device, a testing platform fixedly mounted at a top of the base, a detection device fixedly mounted on a surface of the testing platform, and a display fixedly mounted at a top of the testing platform. The clamping device includes a support frame, a temperature sensor, an electric push rod, a push plate, an elastic telescopic rod, a connecting plate, and sponge blocks. The support frame is fixedly mounted at the top of the base, and the temperature sensor is fixedly mounted at a top of the support frame.

Abstract: A marine floating body is provided with an air chamber, and is configured to float on a sea surface. A wall structure enclosing the air chamber includes a top wall and a side wall. The top wall is fixedly provided with a photovoltaic assembly. The side wall is provided with an inlet check valve. The marine floating body is configured to submerge under large waves to avoid impact and to resurface automatically when conditions calm. A redundant buoyancy of the marine floating body array is controlled so that, under extreme weather, a wind pressure generated by large waves exceeds the buoyancy, causing the array to submerge, and the array resurfaces when the wind and waves diminish. A marine floating body array with a wave-breaking baffle, and a wind-wave resisting method using the same are also provided.

Abstract: A battery management system, an electric vehicle, and a power battery protection method. The battery management system includes a detection board and a control board. The detection board is connected to a vehicle-mounted power battery, and is configured for detecting a cell thermal runaway state of the power battery. The control board is connected to the detection board, and includes a power supply chip and a controller. The detection board is disposed independently of the control board, the detection board is connected to the power supply chip, and the power supply chip is connected to the controller.

Abstract: The present invention includes compositions and methods for retrieving tumor-related antibodies and antigens. In one aspect, the invention includes a method for Sequential Tumor-related Antibody and antigen Retrieving (STAR) which directly and efficiently identifies potent antibodies that can specifically bind to tumor-related antigens on the tumor cell surface. In another aspect, the invention includes a CAR comprising a nanobody, a transmembrane domain, and an intracellular domain, wherein the nanobody is retrieved by a STAR method. In another aspect, the invention includes a CAR T system that targets CD13 and treats acute myeloid leukemia. In another aspect, the invention includes a CAR T system and ADC that targets CDH17 and treats NETs and other types of tumors expressing this antigen, with tolerable toxicities.

Abstract: The present invention discloses a hierarchical and graded source-network-load-storage multi-subject collaborative scheduling method and system, and relates to the technical field of new energy. The method includes: obtaining power supply data, obtaining electricity consumption data corresponding to each level of an urban area, and obtaining energy storage data of electricity storage devices; obtaining historical data sets, and analyzing the power supply data, the electricity consumption data, and the energy storage data to obtain estimated electric energy data; and calling the electricity storage devices in surrounding regions according to the adjusted secondary electricity consumption data of the urban area. The present invention may optimize and schedule on sources, networks, loads, and storage.

Abstract: The present invention discloses an intelligent control system for a distributed photovoltaic power generation cluster, and relate to the field of distributed energy technologies. The intelligent control system includes: a data acquisition module, used for acquiring demand basic data, supply basic data, and fault basic data respectively to form control basic data; a data analysis module, used for analyzing the control basic data to obtain control analysis data; a data processing module, used for processing the control analysis data to obtain a supply and demand balance reference value; and an intelligent control module, used for intelligently controlling the photovoltaic power generation cluster according to the supply and demand balance reference value.

Abstract: The present invention includes compositions and methods for treating AML utilizing bispecific CARs. In certain aspects, the invention includes a bispecific split CAR which binds CD13 and TIM-3 on AML cells.

Abstract: The present disclosure relates to a system and method for capturing movement trajectories of particulate matter. The system includes: micro lidar measurement equipment and a camera. The micro lidar measurement equipment includes: a laser device, a pitching platform, and a protective casing for the laser device, and the laser device is located on the pitching platform. The laser device is configured to emit a laser. The camera is configured to shoot the laser, determine particulate matter concentrations according to a grayscale of pixels and a height of the pixels in a photo shoot, and compare differences in spatial distribution of particulate matter concentrations at different time to obtain the movement trajectories of the particulate matter.