Abstract: Disclosed herein are novel C17-heteroaryl derivatives of oleanolic acid, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds, for example, as antioxidant inflammation modulators, and compositions thereof are also provided.

Abstract: A computing device computes a weight matrix to predict a value for a characteristic in a scoring dataset. For each of a plurality of related tasks, an augmented observation matrix, a plug-in autocovariance matrix, and a plug-in covariance vector are computed. A weight matrix used to predict the characteristic for each of a plurality of variables and each of a plurality of related tasks is computed. (a) and (b) are repeated with the computed updated weight matrix as the computed weight matrix until a convergence criterion is satisfied: (a) a gradient descent matrix is computed using the computed plug-in autocovariance matrix, the computed plug-in covariance vector, the computed weight matrix, and a predefined relationship matrix, wherein the predefined relationship matrix defines a relationship between the plurality of related tasks, and (b) an updated weight matrix is computed using the computed gradient descent matrix.

Abstract: Disclosed are co-crystal forms of N-(2-(5-(((2R,3R,4S,5R)-3,4-dihydroxy-5-methoxy-6,6-dimethyltetra-hydro-2H-pyran-2-yl)oxy)-3?-fluoro-[1,1?-biphenyl]-2-yl)ethyl)-acetamide and L-proline or D-proline, their pharmaceutical compositions, processes of manufacture, and methods of use for treating neurodegenerative disorders such as diabetic peripheral neuropathy.

Abstract: Semiconductor device and fabrication method are provided. The method includes: providing a base substrate with a bottom metallic layer in the base substrate and a dielectric layer on the base substrate; forming interconnect openings through the dielectric layer and exposing the bottom metallic layer, where each interconnect openings includes a contacting hole and a groove on the contacting hole; forming a first conducting layer in the contacting hole, where the first conducting layer is made of a material having a first conductivity along a direction from the bottom metallic layer to a top surface of the first conducting layer; and after forming the first conducting layer, forming a second conducting layer in the groove, where the second conducting layer is made of a material having a second conductivity along a direction parallel to the top surface of the base substrate and the first conductivity is greater than the second conductivity.

Abstract: The process for synthesizing a poly(amic acid) polymer or a polyimide polymer is improved by using a solvent system consisting essentially of: (A) a first component consisting essentially of at least one of a sulfoxide, e.g., DMSO, and an alkyl phosphate, e.g., triethyl phosphate, and (B) optionally, a second component consisting essentially of at least one aprotic glycol ether, e.g., dipropylene glycol dimethyl ether.

Abstract: Solvents useful for removing, among other things, photoresists and poly(amic acid)/polyimide from display/semiconductor substrates or electronic processing equipment, consist essentially of: (A) a first component consisting of at least one of dimethyl sulfoxide (DMSO) and N-formyl morpholine, and (B) a second component consisting of at least one of N,N-dimethyl propionamide, 3-methoxy-N,N-dimethyl propanamide, N,N-dimethyl acetoacetamide and N-methyl-?-caprolactam.

Abstract: Solvents useful for removing, among other things, photoresists and poly(amic acid)/polyimide from display/semiconductor substrates or electronic processing equipment, consist essentially of: (A) a first component consisting of a sulfoxide, e.g., DMSO; (B) a second component consisting of a glycol ether, e.g., ethylene glycol monobutyl ether; and (C) a third component consisting of at least one of N-formyl morpholine, N,N-dimethyl propionamide, 3-methoxy-N,N-dimethyl propanamide, triethyl phosphate, N,N-dimethyl acetamide; N,N-diethyl acetamide, N,N-diethyl propionamide, N-methyl acetamide, N-methyl propionamide, N-ethyl acetamide, and N-ethyl propionamide.

Abstract: The process for synthesizing a poly(amic acid) polymer or a polyimide polymer is improved by using a solvent system consisting essentially of: (A) a first component consisting essentially of N,N-dimethyl propionamide (DMPA), and (B) optionally, a second component consisting essentially of at least one of a sulfoxide, e.g., DMSO, an alkyl phosphate, e.g., triethyl phosphate, and an aprotic glycol ether, e.g., propylene glycol methyl ether acetate.

Abstract: The present invention discloses a method and an apparatus for sending a search request. The method includes: during a running procedure of a search engine client, generating a forged search request, where the forged search request carries a forged search word; and sending the forged search request to the search engine server. The forged search request is sent to the search engine server, to serve as a factor interfering with an analysis of a user behavior by the search engine server based on a true search request, to prevent the search engine server from analyzing the user behavior based on a search word entered by a user, thereby improving user experience. It is avoided that, in the prior art, a search engine server analyzes a user behavior based on a search word entered by a user.

Abstract: The present disclosure provides a method for processing display contents, a first electronic device, and a second electronic device thereof. The method of displaying contents includes the steps of: providing a first electronic device configured to display one or more virtual contents to a user, wherein the first electronic device is communicable with and coupled to a second electronic device, which includes a physical display configured to display one or more non-virtual contents; determining the user's line of sight; and prohibiting the physical display of the second electronic device from displaying the one or more non-virtual contents, in response to the user's line of sight not being on the physical display of the second electronic device.

Abstract: The present disclosure provides a display screen processing method. Application scenario information of one or more virtual display screens displayed by a first electronic device through an optical lens module is determined. The first electronic device is coupled with a second electronic device that includes a physical display screen. A display parameter of the one or more virtual display screens is adjusted based on the application scenario information.

Abstract: Disclosed herein are C4 modified oleanolic acid derivatives of the formula: Formula (X) or Formula (XII), as well as analogs thereof, wherein the variables are defined herein. In addition, disclosed herein are pharmaceutical compositions of these derivatives or analogs, methods for their manufacture, and methods for their use, including for the prevention and treatment of diseases or disorders associated with overproduction of IL-17.

Abstract: A method, device and system for cutting a bogie brake off are disclosed. The method includes that: when a bogie brake is not able to be relieved, a cutting-off instruction output from an Operating Control Center (OCC) is received, wherein the cutting-off instruction is used for triggering an action of cutting the bogie brake off; a logic operation is performed on the cutting-off instruction to obtain an isolation control instruction; and an electromagnetic valve corresponding to a bogie is controlled to act according to the isolation control instruction, so as to cut the bogie brake off. According to the method, the technical problem that a brake cutting-off valve is set under a passenger seat to cut a single bogie brake off in the existing urban rail vehicle, but the requirements of an unmanned vehicle cannot be met is solved.

Abstract: A synchronization system based on wireless or limited cable interconnection is disclosed, which includes a central unit comprising a delay compensation module, and RF transmission channels. At least one channel comprises a clock controller and a synchronization controller. The central unit transmits a controlled clock signal and a controlled synchronization signal to the at least one channel, and receives a clock echo signal and a synchronization echo signal. The delay compensation module estimates a clock phase compensation based on the controlled clock signal transmitted and the clock echo signal received, and a synchronization delay compensation based on the controlled synchronization signal transmitted and the synchronization echo signal received. The clock controller and the synchronization controller adjusts respectively a clock signal and a synchronization signal received from the at least one channel based on the clock phase compensation and the synchronization delay compensation.

Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.

Abstract: A fault diagnosis method for a big-data network system includes extracting fault information from historical data in the network system, to form training sample data, which is trained to obtain a deep sum product network model that can be used to perform fault diagnosis; and diagnosing a fault of the network system based on the deep sum product network model. The embodiments of the present application resolve a problem that it is difficult to diagnose a fault of a big-data network system.

Abstract: A power conversion system is disclosed, which comprises at least one conversion unit comprising a converter unit and a first power interface boards; at least one measurement unit comprising a measurement board and a second power interface boards; and a controller comprising a processing unit, and a third power interface board communicated with the processing unit, and the first power interface board and the second power interface board, wherein at least some of the communications between the third power interface board and the first and second power interface boards have independent bandwidths.

Abstract: A semiconductor device and fabrication method thereof are provided. The fabrication method include: providing a to-be-etched material layer; forming a plurality of discrete sacrificial layers on the to-be-etched material layer; forming first initial spacers on sidewalls of each sacrificial layer, where each first initial spacer includes a first bottom region and a first top region on the first bottom region; removing the sacrificial layers; removing the first bottom region of the first initial spacer to form a first spacer from the first top region; forming second spacers on sidewalls of each first spacer; removing the first spacer; and etching the to-be-etched material layer by using the second spacers as an etch mask.

Abstract: A radio frequency (RF) amplification method, comprising: modulating a first digital carrier signal with a digital envelop signal to generate digital RF pulse signals having a first frequency, converting the digital RF pulse signals into analog RF pulse signals, amplifying the analog RF pulse signals to generate an RF output signal, converting an analog feedback signal sampled from the RF output signal into digital feedback signals; demodulating the digital feedback signals with a second digital carrier signal to generate an in-phase (I) signal and a quadrature (Q) signal, and generating an amplitude setting signal for adjusting an amplitude of the digital envelop signal and a phase setting signal for adjusting a phase of the first digital carrier signal according to the I signal and the Q signal.

Abstract: Disclosed is an alarming and unlocking device. The alarming and unlocking device is installed in a passenger carriage and includes a control switch (10), a communication device, and a locking device, wherein the control switch (10) is provided with an alarming position (11) and an unlocking position (12); the control switch (10) is in signal connection with the communication device; when the control switch (10) is located at the alarming position (11), the communication device is started to receive and send a voice signal; the locking device is installed on a door so as to control the door to lock or unlock; the control switch (10) is in signal connection with the locking device; and when the control switch (10) is located at the unlocking position (12), the locking device performs an unlocking operation. According to the alarming and unlocking device, the problem that a structure for an alarming and unlocking device on a vehicle is relatively complex in the conventional art is solved.