Abstract: The description relates to automated binary code summarization. In one example, a binary code summarization tool receives binary code and combines the received binary code with natural language in a prompt for a large language model (LLM). The binary code summarization tool receives a semantic summarization from the LLM relating to the received binary code and evaluates the new semantic summarization for malicious functionality in the received binary code.

Abstract: Provided is a base mutation detection method, which includes: determining an initial frequency of sequencing data of samples being a specific base at an interested locus; calculating, based on the initial frequency, an expected value of each sample being the specific base at the interested locus; updating the initial frequency of the sequencing data of the samples being the specific base at the interested locus; further calculating the expected value of each sample being the specific base at the interested locus, further updating the initial frequency of the sequencing data of the samples being the specific base at the interested locus, and repeating the foregoing iteration until the expected value of each sample being the specific base at the interested locus converges; and determining, based on each converging expected value, a base mutation type and a mutation confidence at the interested locus of each sample.

Abstract: Described herein are methods and uses thereof for in vivo evaluating functions of multiple genes in parallel by combining in utero genetic perturbation of progenitor cells and single-cell transcriptomic profiling of progeny cells in animals. These methods can be used, among other things, to reveal in vivo gene functions in a cell type-specific manner.

Abstract: The present invention relates to bifunctional compounds, which find utility as modulators of targeted ubiquitination, especially inhibitors of a variety of polypeptides and other proteins which are degraded and/or otherwise inhibited by bifunctional compounds according to the present invention. In particular, the present invention is directed to compounds, which contain on one end a VHL ligand which binds to the ubiquitin ligase and on the other end a moiety which binds a target protein such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of that protein. The present invention exhibits a broad range of pharmacological activities associated with compounds according to the present invention, consistent with the degradation/inhibition of targeted polypeptides.

Abstract: The present disclosure provides a method for extracting lithium using a resin adsorbent to pretreat low-grade deep brine, which relates to the technical field of lithium extraction from brine. In the present disclosure, resin adsorbent is used to perform adsorption pretreatment on the concentrated brine, which can adsorb organic impurities in the concentrated brine without adsorbing lithium ions, so that the concentration of lithium ions is almost unchanged compared with the feed material, with the subsequent manganese-based lithium adsorbent, the adsorption rate of lithium can be increased by 41%; At the same time, pretreating the concentrated brine using resin adsorbents has shorter steps, less materials, and does not produce a large amount of low-value product gypsum, which makes the lithium extraction process simpler and easier to operate, and reduces production costs.

Abstract: A static CT apparatus and an imaging method for the same are provided. The imaging method includes: acquiring initial projection data of an inspected object at different angles by using a distributed ray source and a detector, where the initial projection data includes projection data that is directly obtained by the detector based on the rays emitted from a plurality of ray source points; obtaining a first CT image using a reconstruction algorithm according to the acquired initial projection data; dividing the first CT image into N first sub-images, where N is a positive integer greater than or equal to 1, and a union of the N first sub-images covers the entire first CT image; optimizing the N first sub-images to obtain N second sub-images; and merging the N second sub-images to obtain a second CT image.

Abstract: The present application provides a displaying base plate and a displaying device, which relate to the technical field of displaying. The displaying base plate can effectively reduce the width of the non-displaying region, so as to realize a narrow border frame, and accordingly increase the screen-to-body ratio. The displaying base plate includes: a displaying region; and a non-displaying region surrounding the displaying region, wherein the non-displaying region includes a first dam region, the first dam region surrounds the displaying region; and the first dam region includes a dam, at least one blocking unit located at one side of the dam away from the displaying region, the dam and the blocking unit are disposed within at least a part of the first dam region, and the blocking unit is patterned.

Abstract: An efficient transplanting device with an automatic seedling pick-up and supplementation function includes a seedling pick-up device, a seedling discharging device, and a seedling supplementation device. The seedling discharging device is used to discharge plug seedlings for transplantation; the seedling pick-up device is used to transfer the plug seedlings and the seedling supplementation device is used to supplement the plug seeding. A seedling pick-up photoelectric sensor, a detection camera, and a controller are provided for the operations of plug seedling pick-up, supplementation and discharge of the plug seedlings.

Abstract: A method controls the duty cycle distortion of clock signals. An electronic device obtains an input clock signal and generates a first output voltage and a second output voltage from the input clock signal. The first output voltage has a first direct current (DC) voltage level indicating, in real time, a first duty cycle length of high voltage duty cycles of the input clock signal. The second output voltage has a second DC voltage level indicating, in real time, a second duty cycle length of low voltage duty cycles of the input clock signal. The difference between the first and second DC voltage levels corresponds to the duty cycle distortion level of the input clock signal. A duty cycle control signal is generated based on the difference between the first and second DC voltage levels to control the high voltage duty cycles of the input clock signal.

Abstract: A method may include receiving input for a multiwell structure and subsurface target locations, where the multiwell structure includes slots; generating, based at least in part on the input, a position for the multiwell structure, slot-well assignments for the slots, and well trajectories, where each of the well trajectories extends from an assigned one of the slots to one or more of the subsurface target locations; and outputting a set of specifications for the position for the multiwell structure, the well trajectories, and an order for drilling the well trajectories.

Abstract: An anti-DLL3 antibody and a pharmaceutical use thereof, and an antibody-drug conjugate containing the anti-DLL3 antibody. The present disclosure relates to an anti-DLL3 antibody-ecteinascidin drug conjugate represented by general formula (Pc-L-D), wherein Pc is the anti-DLL3 antibody.

Abstract: The present invention provides a sounding device including a housing body having a containment cavity and a sounding unit placed in the containment cavity. The sounding unit includes a vibration system and a magnetic circuit system. The sounding device includes a box, a coil, a circuit board, and an elastic assembly. The elastic assembly is used to suspend the box in the containment cavity. The present invention coil shares a magnetic circuit system with the vibration system and the sounding unit is directly used as the weight unit of the coil. The parts are shared to the greatest extent, the assembly process is simplified, and the cost is reduced.

Abstract: Provided is speaker, including magnetic circuit unit, frame fixed to the magnetic circuit unit, and first and second sound-producing unit both fixed to the frame. The magnetic circuit unit includes magnetically conductive assembly with lower clamping plate and magnet component located on lower clamping plate. A third magnetic conductor is arranged around the magnet component, first magnetic conductor, and second magnetic conductor. A first and a second voice coil are respectively located in magnetic gaps between third magnetic conductor and second magnetic conductor and between third magnetic conductor and first magnetic conductor. The two sound-producing units share the magnetic circuit unit. The frame includes a first and a second main body portion arranged coaxially and connected to each other, a first diaphragm is fixed to second main body portion, and second diaphragm is fixed between first main body portion and second main body portion.

Abstract: Disclosed is a blade apparatus for wind power generation, which includes: a blade body, one end thereof being provided with a blade-root connecting portion; and a blade root assembly, including a plurality of blade root segments arranged in a circumferential direction of the blade body to form a body of revolution, each blade root segment being detachably connected to a corresponding portion of the blade-root connecting portion. The blade root assembly with a plurality of blade root segments is adopted, so that the dimension of a single blade root segment is greatly reduced, thus effectively reducing the difficulties in manufacture and transportation. Meanwhile, the overall dimension of the blade root assembly can be further increased to match with a larger blade body, which is beneficial to further improve the swept area of blade and generated output of wind power generation device.

Abstract: Provided are an adenosine triphosphatase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 (ATP2A2) gene-based molecular marker for identifying a chicken feed efficiency trait, and an identification method and use thereof. A nucleotide sequence of the molecular marker is shown in SEQ ID NO: 1, and a base at locus 926 in the nucleotide sequence is T or G. In the present application, by identifying a genotype of the molecular marker in a chicken genome and then selecting the chicken feed efficiency trait according to the genotype, a breeding method for early selection of the poultry feed efficiency trait is established. The method is simple, rapid, and low-cost, does not require special instruments, and is suitable for the needs of marker-assisted selection experiments.

Abstract: A calibration assembly, including: a base; and a plurality of calibration wires dispersedly connected to the base. An absorption capacity of the calibration wire for X rays is greater than that of the base for X rays. Through a specific structure design of a plurality of calibration wires in the calibration assembly, the calibration wires are dispersedly connected to the base, and taking advantage of the characteristics that the absorption capacity of the calibration wire for X rays is greater than that of the base for X rays, the calibration wires are applied to the calibration phantom, and the calibration phantom is scanned in the scanning system. By continuously adjusting the geometric parameter values in the imaging method, the optimal geometric parameter values that are closest to the real scanning system structure may be obtained, thereby improving the imaging effect of the scanning system.

Abstract: An inspection system and method, the inspection system includes: a carrying device, at least one ray source and a detector assembly. The ray source and the detector assembly are lifted or lowered along a central axis of the carrying device relative to the carrying device. When viewed along the central axis, the ray source is translatable between scanning positions relative to the carrying device. When the ray source is at one of the scanning positions the ray source and the detector assembly are lifted or lowered relative to the carrying device along the central axis, and the ray source emits X-rays; and when the ray source and the detector assembly are lifted or lowered a predetermined distance the ray source translates to another scanning position. The inspection system further reconstructs a three-dimensional scanning image of the object to be inspected based on detection data of the detector assembly.

Abstract: Disclosed are an imidazothiazole derivative, a preparation method therefor, and an application thereof. The imidazothiazole derivative has a structure represented by formula (I): R1 and R3 are each independently selected from optionally substituted five-membered to six-membered heterocyclyl containing one to two nitrogen atoms, and R2 and R4 are each independently selected from optionally substituted aryl or heteroaryl. The imidazothiazole derivative has good MNK inhibitory activity, excellent selectivity, and an excellent in vivo hypoglycemic effect, and has a wide medicinal background.

Abstract: A tiled display device includes: a first display device including: a first display substrate having a plurality of light emitting areas; and a second color conversion substrate comprising a plurality of light transmitting areas respectively corresponding to the light emitting areas and comprising a light scattering material and a plurality of light blocking areas between the light transmitting areas; a second display device comprising a second display substrate and a second color conversion substrate, the second display device being at a side of the first display device; and a light scattering member between the first display device and the second display device and comprising a light scattering material, wherein an external light reflectance of the light scattering member is higher than an average value of an external light reflectance of the light transmitting areas and an external light reflectance of the light blocking areas.