Abstract: The present disclosure provides a preparation method of nano-aluminum oxide (nano-Al2O3) with a controllable hydroxyl content, belonging to the technical field of nano-alumina. H2O2 dissolved in water dissociates a large number of hydroxyl radicals. In the present disclosure, a resulting H2O2 solution is used as a solvent for precipitation; during the precipitation, a soluble aluminum salt and a pore-enlarging agent are reacted to generate a precipitate under alkaline conditions, and the hydroxyl radicals are distributed on a surface of the precipitate. During drying, the hydroxyl radicals are converted into bound water and distributed on a surface and in pores of an aluminum hydroxide precursor; during roasting, the bound water is destroyed to form hydroxyl. The hydroxyl content of the nano-Al2O3 can be regulated by controlling a concentration of the H2O2 solution, and the nano-Al2O3 has the hydroxyl content positively correlated with the concentration of the H2O2 solution.

Abstract: An apparatus and method for transmitting data of vehicle communication (V2X) services and a communication system. The apparatus includes: a first generating unit configured in a media access control (MAC) layer of the terminal equipment and configured to generate at least one protocol data unit (PDU) in a mode identical to a transmission mode to which a service data unit (SDU) contained in a PDU corresponds; and a first transmitting unit configured in the MAC layer and configured to transmit the PDU to a physical layer of the terminal equipment, and notify the transmission mode to which the PDU corresponds to the physical layer. This disclosure facilitates the physical layer to transmit data in a corresponding transmission mode. The terminal equipment may determine the transmission mode or set the transmission mode according to the indication information, and layers of the terminal equipment perform corresponding processing.

Abstract: The optical fibers disclosed have single mode and few mode optical transmission for VCSEL-based optical fiber transmission systems. The optical fibers have a cable cutoff wavelength ?C of equal to or below 1260 nm thereby defining single mode operation at a wavelength in a first wavelength range greater than 1260 nm and few-mode operation at a wavelength in a second wavelength range from 970 nm and 1070 nm. The mode-field diameter is in the range from 9.3 microns to 10.9 microns at 1550 nm. The optical fibers have an overfilled bandwidth OFL BW of 1 GHz.km to 3 GHz.km at the at least one wavelength in the second wavelength range. VCSEL based optical transmission systems and methods are disclosed that utilize both single core and multicore versions of the optical fiber.

Abstract: The present invention is directed to certain 2-aminoquinzaoline derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R3, R4, X1, and X2 are as defined herein, which are potent inhibitors of LRRK2 kinase and may be useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease and other diseases and disorders described herein. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which LRRK-2 kinase is involved.

Abstract: A method and device for detecting circulating abnormal cells. The method for detecting the circulating abnormal cells comprises: respectively segmenting and labelling, by using an image processing algorithm and a morphological algorithm, cell nuclei included in dark field microscope images of a plurality of probe channels (101); inputting the dark field microscope images, in which cell nuclei are labelled, of the plurality of probe channels into a pre-built circulating abnormal cell detection model to acquire the number of staining signals included in each labelled cell nucleus in the dark field microscope image of each probe channel (102); and for each labelled cell nucleus, on the basis of the number of the staining signals included in the labelled cell nucleus in the acquired dark field microscope image of each probe channel, determining whether the labelled cell nucleus belongs to a circulating abnormal cell (103).

Abstract: The present disclose provides methods for treating neuroinflammation. Compositions having therapeutic agents targeted to interfering with succinate/succinate receptor signaling are administered to reduce or ameliorate neuroinflammation. The neuroinflammation may be associated with, caused by, or result from diseases/pathologies/disorders associated with the central nervous system.

Abstract: Disclosed is methods and systems for configuring bone conduction hearing aids. The method may comprise: obtaining hearing loss data of a wearer; determining a reference output parameter of the bone conduction hearing aid at each sound level in each frequency band based on the hearing loss data; obtaining an adjustment value of the reference output parameter at the each sound level in the each frequency band, wherein the adjustment value is at least related to the frequency band; and configuring the bone conduction hearing aid based on the reference output parameter and the adjustment value at the each sound level in the each frequency band.

Abstract: This application relates to the field of communications technologies, and provides ambient light and optical proximity detection methods, a photographing method, and a terminal, so that an entire display screen of the terminal is used to display a user interface, and this improves user experience. The method specifically includes: controlling, by a terminal, some areas of a display screen to display a black picture for a plurality of times; and when the areas display the black picture, obtaining an intensity of ambient light detected by an ambient light sensor to adjust luminance of the display screen.

Abstract: The present invention relates to processes for preparing a compound of Formula (A): or a pharmaceutically acceptable salt or solvate thereof. Compound of Formula (A) and pharmaceutical compositions are useful as SARS-CoV-2 3CL pro inhibitors.

Abstract: An audio control method, a system, and device, the method including displaying, by a first device, in response to a first user operation, a candidate device list, obtaining, in response the user selecting a second device from the candidate device list, an audio capability parameter of the second device indicating a hardware capability and a software capability for playing audio, determining a first audio play policy based on the audio capability parameter of the second device, obtaining second audio data by the first device by performing first processing on first audio data from a first audio application according to the first audio play policy, and sending, by the first device, the second audio data to the second device, so that second device plays the second audio data or processes the second audio data and plays processed second audio data.

Abstract: Embodiments of this application disclose a radio frequency unit, an antenna, and a signal processing method. The method includes: receiving an uplink signal in a downlink slot, where the uplink signal includes signals of N frequency bands; filtering and amplifying the signals of the N frequency bands; converting the uplink signal into a digital intermediate frequency signal; and then processing the digital intermediate frequency signal.

Abstract: Disclosed herein are methods for selecting a patient suffering from fungal-associated intestinal inflammation for treatment with an IL-1 pathway inhibitor, including inflammasome-blocking drugs based on the presence of candidalysin-secreting C. albicans strains in gut tissue.

Abstract: A hybrid quantum-classical cloud platform and a task execution method. The cloud platform comprises: an SaaS layer for providing a user interface so as to acquire, by means of the user interface, a hybrid quantum-classical programming language corresponding to a task to be executed; a PaaS layer for performing algorithm compilation and task separation on the hybrid quantum-classical programming language to obtain a quantum computing task and a classical computing task corresponding to the task to be executed, and respectively allocating resources to the quantum computing task and the classical computing task; and an IaaS layer for executing the quantum computing task using a quantum virtual machine and executing the classical computing task using a classical server according to the resource allocation condition of the PaaS layer. Therefore, the communication overhead and the data delay can be reduced, the task processing efficiency is improved, and the quantum computing advantage is exerted.

Abstract: A human-computer interaction system and method based on a wireless charging device are provided. The system includes: a multi-coil wireless charging circuit, including wireless charging coils arranged in a 3*3 matrix; a power information collection circuit, configured to acquire power data of each of at least two wireless charging coils of the wireless charging coils when the wireless charging device slides through the at least two wireless charging coils; a data processing circuit, configured to generate a motion trajectory of the wireless charging device based on the power data of each of the at least two wireless charging coils, and identify a user instruction corresponding to the motion trajectory using a preset instruction identification model, the instruction identification model being a neural network model based on deep supervised learning; and a cloud server, configured to control a smart home device based on the user instruction.

Abstract: A detection element, a manufacturing method thereof and a flat panel detector are disclosed. The detection element includes: a base substrate; a first electrode on the base substrate; a photoelectric conversion layer; a transparent electrode and a second electrode electrically connected with the transparent electrode on a side of the photoelectric conversion layer away from the first electrode. An orthographic projection of the photoelectric conversion layer on the base substrate completely falls within an orthographic projection of the first electrode on the base substrate, in a plane parallel to the base substrate, the transparent electrode is located at a middle portion of the photoelectric conversion, an orthographic projection of the second electrode on the base substrate includes a ring surrounding an orthographic projection of the transparent electrode on the base substrate.

Abstract: The present disclosure is directed to methods and compositions for the prediction and treatment of immunotherapy-induced toxicities, as well as improved methods for the treatment of cancer with immunotherapies.

Abstract: The present invention provides a method of calibrating gamma-ray and photon counting detectors, including, but not limited to, monolithic crystal detectors. The method of the present invention is based on the observation that measurement of fan beam datasets allows the synthesis of collimated beam data to derive MDRFs by use of an algorithm that finds the common or intersecting data subsets of two or more orthogonal calibration datasets. This makes the calibration process very efficient while still allowing the full benefits of maximum-likelihood event-parameter estimation that incorporates the statistical nature of the light sensor measurements.

Abstract: Provided is a laser. The laser includes: a base plate, an annular side wall, a plurality of conductive pins, a plurality of light-emitting chips, and a plurality of conductive wires; wherein the side wall and the plurality of light-emitting chips are disposed on the base plate, the side wall surrounds the plurality of light-emitting chips, the plurality of conductive pins are extended through the side wall and are affixed into the side wall, and sides, distal from the base plate, of portions of the plurality of conductive pins surrounded by the side wall include planar regions, wherein the planar region of each of the plurality of conductive pins is connected to the light-emitting chip via the conductive wire.

Abstract: A method and apparatus for learning graph representations for out-of-distribution generalization.

Abstract: A high-speed transimpedance amplifier with bandwidth extension feature over full temperature range and bandwidth extension method belong to the field of integrated circuit. The present invention solves the problem existed in boosting core amplifier bandwidth technology over full temperature range. The present invention includes a preamplifier TIA, a phase splitting stage PS, a pre-driver stage Pre-Drive, an output buffer BUFF and an offset cancelation circuit OC. The preamplifier TIA adopts the gate-drain voltage cancelation technology to expand the bandwidth, so that its ?3 dB bandwidth is greater than twice the closed-loop bandwidth of the first-order TIA. The pre-driver stage Pre-Drive is used to drive the output buffer BUFF. By adjusting the source-level negative feedback capacitance value of the pre-driver stage Pre-Drive circuit to generate a high-frequency gain that varies with temperature, the preamplifier TIA bandwidth differences under different temperature conditions are compensated.