Abstract: A multi-layer light source includes an emissive layer and a textured lighting gel layer, the lighting gel layer being situated between the emissive layer and a 2D canvas or a 3D object. User inputs controlling the multi-layer light source are received, these user inputs being provided with the user interacting with the 2D canvas without switching to editing in 3D space. The multi-layer light source is configured based on the user inputs and, based on the configuration, emission of light rays from the multi-layer light source is determined. Areas of shadows cast by 3D objects are also determined. An image generation system determines, a color of a location (e.g., a pixel) on the 2D canvas or the 3D object that a light ray intersects based on the color that is in the lighting gel layer that the light ray passes through.

Abstract: A compound represented by formula I or a pharmaceutically acceptable salt thereof and a use thereof in preparing a drug for treating, stopping or preventing a disease or disorder mediated by FGFR4 activity.

Abstract: The present invention provides therapeutic and diagnostic methods and compositions for cancer, for example, lung cancer (e.g., NSCLC), bladder cancer (e.g., UC), kidney cancer (e.g., RCC), breast cancer (e.g., TNBC), or melanoma. The invention provides methods of treating cancer (e.g., lung cancer (e.g., NSCLC), bladder cancer (e.g., UC), kidney cancer (e.g., RCC), breast cancer (e.g., TNBC), or melanoma), methods of determining whether a patient suffering from cancer (e.g., lung cancer (e.g., NSCLC), bladder cancer (e.g., UC), kidney cancer (e.g., RCC), breast cancer (e.g., TNBC), or melanoma) is likely to respond to treatment comprising a PD-L1 axis binding antagonist, methods of predicting responsiveness of a patient suffering from cancer (e.g., lung cancer (e.g., NSCLC), bladder cancer (e.g., UC), kidney cancer (e.g., RCC), breast cancer (e.g., TNBC), or melanoma) to treatment comprising a PD-L1 axis binding antagonist, and methods of selecting a therapy for a patient suffering from cancer (e.g.

Abstract: The present application refers to secondary battery and battery module, battery pack and apparatus including the secondary battery. In particular, the secondary battery includes a housing as well as an electrode assembly and an electrolyte contained in the housing; the electrode assembly includes a positive electrode plate, a negative electrode plate and a separator, and the positive electrode plate includes a positive current collector and a positive electrode film that is disposed on at least one surface of the positive electrode current collector and includes a positive electrode active material; the positive electrode active material includes one or more of lithium nickel cobalt manganese oxide and lithium nickel cobalt aluminum oxide; the negative electrode plate includes a negative electrode current collector and a negative electrode film that is disposed on at least one surface of the negative electrode current collector and includes a negative electrode active material.

Abstract: Receive, by a price calculation microservice, tenant user input from a particular tenant of a multi-tenant system. Generate, by the price calculation microservice, a particular charge model based on the tenant user input. Detect, by a usage microservice, a usage event associated with a customer of the particular tenant of the multi-tenant system. Receive, by a rating microservice, a rating request, the rating request being received in response to the detecting the usage event. Calculate, by the price calculation microservice in response to the receiving the rating request, a usage charge for the usage event based on the particular charge model. Store, by the rating microservice, the usage charge. Generate an invoice based on the usage charge stored by the rating microservice. Provide the invoice to the customer of the particular tenant of the multi-tenant system.

Abstract: The present invention provides therapeutic and diagnostic methods and compositions for cancer, for example, bladder cancer. The invention provides methods of treating bladder cancer, methods of determining whether a patient suffering from bladder cancer is likely to respond to treatment comprising a PD-L1 axis binding antagonist, methods of predicting responsiveness of a patient suffering from bladder cancer to treatment comprising a PD-L1 axis binding antagonist, and methods of selecting a therapy for a patient suffering from bladder cancer, based on somatic mutation levels of genes of the invention (e.g., somatic mutation levels in a tumor sample obtained from the patient).

Abstract: A cavity plate assembly (400) for a preform mold (100), which includes a cavity plate (410) having an array of seats (412) and a corresponding array of cavity inserts (440) mounted to a front face (CVF) of the cavity plate (410) and in communication with a respective seat (412). Each cavity insert (440) includes a body (441) with a mounting face (441a) and a spigot (443) projecting from the mounting face (441a) and received in a respective seat (412) of the cavity plate (410) such that the mounting (441a) face abuts the front face (CVF) of the cavity plate (410). Each cavity insert (440) also includes a molding surface (448) along its length, at least two thirds of which extends beyond the cavity plate (410).

Abstract: A method for joining dissimilar materials is provided. The method includes a solid-state joining process in which a rivet is plunged into a predrilled hole in a top workpiece. When the rivet contacts the bottom workpiece, ultrasonic vibration by oscillatory motion of a sonotrode, such as horizontal, vertical, or rotational motion, creates frictional heat at the interface between the rivet and the lower workpiece. With the aid of frictional heat and axial compression, metallurgical bonding is achieved at the interface between the rivet and the bottom sheet, while being below the melting temperature of the bottom workpiece. The sonotrode is retracted while the rivet remains.

Abstract: The present disclosure relates to the technical field of industrial waste gas purification, in particular to a core-shell structured catalyst, a preparation method and use thereof. The present disclosure provides a core-shell structured catalyst including a metal oxide-molecular sieve as a core and porous silica (SiO2) as a shell, where the metal oxide-molecular sieve includes a molecular sieve and a metal oxide loaded on the molecular sieve, the metal oxide includes an oxide of a first metal and an oxide of a second metal, the first metal is Fe, Cu, Ti, Ni or Mn, and the second metal is Ce or La. The core-shell structured catalyst of the present disclosure can enable effective removal of HCN and AsH3 at the same time with a stable effect, and no secondary pollution.

Abstract: The present invention comprises chlorinated and non-chlorinated alkaline cleaning compositions for removal of proteinaceous and fatty soils at low temperature, i.e. less than 120° F., with little or no deleterious affect on cleaning performance. According to the invention, applicants have found that adding additional alkalinity makes protein removal more difficult and reducing the amount of alkalinity actually improves performance. According to the invention optimized combinations of chlorine and alkalinity components for low temperature cleaning as well as a surfactant system optimized for low temperature fatty soil removal are disclosed.

Abstract: In some embodiments, a computing device uses a blue noise sampling operation to identify source pixels from an input image defining respective pixel sets. Each pixel set is associated with a respective weight matrix for a down-scaling operation. The blue noise sampling operation causes an overlap region between first and second pixel sets. The computing device assigns an overlap pixel in the overlap region to the first weight matrix based on the overlap pixel being closer to the first source pixel. The computing device modifies the second weight matrix to exclude the overlap pixel from a portion of the down-scaling operation involving the second weight matrix. The computing device performs the down-scaling operation on the input image by combining the first pixel set into a first target pixel with the first weight matrix and combining the second pixel set into a second target with the modified second weight matrix.

Abstract: An apparatus, a method, and a system. The method includes implementing an erase operation on a deck of a superblock, block or subblock of a three-dimensional (3D) non-volatile memory device to obtain an erased deck; applying a dummy read pulse to one or more wordlines (WLs) of a to-be-read deck of the superblock, block or subblock; and implementing, after application of the dummy read pulse, a read operation on one or more memory cells corresponding to the one or more WLs to read data from the one or more memory cells.

Abstract: A method of forming a silicon germanium layer on a surface of a substrate and a system for forming a silicon germanium layer are disclosed. Examples of the disclosure provide a method that includes providing a plurality of growth precursors to control and/or promote parasitic gas-phase and surface reactions, such that greater control of the film (e.g., thickness and/or composition) uniformity can be realized.

Abstract: A concentrated liquid sanitizing and rinse composition containing peroxycarboxylic acid(s) and compatible rinse aid surfactants is disclosed. The sanitizing and rinsing compositions are formulated in a single liquid concentrate, replacing a traditional dual product of a sanitizer and rinse aid. The sanitizing and rinsing chemistries are particularly effective at neutral pHs against gram negative organisms at elevated temperatures. Methods of using the concentrated liquid sanitizing and rinse composition are also disclosed.

Abstract: The invention belongs to the technical field of the resource treatment of industrial wastes, and particularly relates to a method for preparing a cementing material using smelting industrial waste slag after utilizing the simultaneous removal of SO2 and NOx in flue gas and an application of the cementing material obtained by the same. According to the invention, SO2 and NOx in the flue gas can be treated with the smelting industrial waste slag, meeting requirement of flue gas desulfurization and denitration; moreover, the smelting industrial waste slag can be purified and separated by means of waste gas resources to obtain a cementing material, realizing the resource utilization of the smelting industrial waste slag and waste gas.

Abstract: Methods and systems for forming structures including one or more layers comprising silicon germanium and one or more layers comprising silicon are disclosed. Exemplary methods can include using a surfactant, using particular precursors, and/or using a transition step to improve an interface between adjacent layers comprising silicon germanium and comprising silicon.

Abstract: The present disclosure is directed toward systems, methods, and non-transitory computer readable media for generating a modified digital image by identifying patch matches within a digital image utilizing a Gaussian mixture model. For example, the systems described herein can identify sample patches and corresponding matching portions within a digital image. The systems can also identify transformations between the sample patches and the corresponding matching portions. Based on the transformations, the systems can generate a Gaussian mixture model, and the systems can modify a digital image by replacing a target region with target matching portions identified in accordance with the Gaussian mixture model.

Abstract: A compound represented by formula I or a pharmaceutically acceptable salt thereof and a use thereof in preparing a drug for treating, stopping or preventing a disease or disorder mediated by FGFR4 activity.

Abstract: Introduced here are techniques for relighting an image by automatically segmenting a human object in an image. The segmented image is input to an encoder that transforms it into a feature space. The feature space is concatenated with coefficients of a target illumination for the image and input to an albedo decoder and a light transport detector to predict an albedo map and a light transport matrix, respectively. In addition, the output of the encoder is concatenated with outputs of residual parts of each decoder and fed to a light coefficients block, which predicts coefficients of the illumination for the image. The light transport matrix and predicted illumination coefficients are multiplied to obtain a shading map that can sharpen details of the image. Scaling the resulting image by the albedo map to produce the relight image. The relight image can be refined to denoise the relight image.

Abstract: A compound represented by formula I or a pharmaceutically acceptable salt thereof and a use thereof in preparing a drug for treating, stopping or preventing a disease or disorder mediated by FGFR4 activity.