Abstract: Feedback is collected from a user during log-on to a system. The feedback from the user can be used to enhance a knowledge base. The feedback is required from the user in order for the user to gain access to the system.

Abstract: Potassium chloride cotransporter-2 (KCC2) plays a critical role in brain function, and deficiency in KCC2 has been linked to neurological diseases, psychiatric disorders, and central nervous system injuries. In particular, Rett syndrome (RTT), a severe neurodevelopmental disorder caused by mutations in the X-linked gene Methyl CpG binding Protein 2 (MECP2), has been linked to deficits in KCC2. The disclosure reports the use of CRISPR/Cas9 genome-editing technology to generate stem cell-derived, genetically defined KCC2 reporter human neurons for large-scale compound screening. This screening platform has been utilized to identify a number of small molecule compounds that are capable of enhancing KCC2 expression in both wild-type and RTT neurons, as well as organotypical brain slices cultured from wild-type mice.

Abstract: In an embodiment, the present disclosure pertains to a cavitation generation device that includes a dactyl plunger rotatable about an axis between an open position and a closed position and a propus socket having a channel. The propus socket is rigidly mounted below the dactyl plunger, and the dactyl plunger is received into the propus socket when the dactyl plunger is in the closed position. The cavitation generation device can also include a torsion spring that biases the dactyl plunger into contact with the propus socket. In another embodiment, the present disclosure pertains to a method of inducing a cavitation including biasing a dactyl plunger via a torsion spring, and rotating the dactyl plunger, by action of the torsion spring, into a propus socket. The propus socket includes a nozzle-shaped channel. The method further includes ejecting a socket cavity volume through the nozzle-shaped channel thereby inducing a cavitation event.

Abstract: The present disclosure relates to data processing methods and devices. One example method includes obtaining N correctly received radio link control (RLC) protocol data units (PDUs) in a packet data convergence protocol (PDCP) PDU, and generating the PDCP PDU based on the N correctly received RLC PDUs, where the PDCP PDU includes M RLC PDUs, N and M are positive integers, and N<M.

Abstract: The present disclosure discloses preparation of M. alpina CCFM698 thalli and application thereof in a feed additive, and belongs to the field of biological engineering and feed additives. The total fatty acid content of the M. alpina dried thalli obtained by the present disclosure is 30%-40% by weight of the dried thalli, and the EPA content is 24% or more by weight of total fatty acids. The dosage of the dried thalli in the feed in the disclosure is 0.5-1.5% of the total weight of the basal feed. The thallus feed additive is reasonable in fatty acid composition and very high in EPA content and can be used for producing high-DHA eggs which are beneficial to body health of eaters. The DHA content in each of eggs laid by laying hens fed with the feed containing the feed additive of the present disclosure reaches about 120 mg which is obviously higher than that in the prior art.

Abstract: An apparatus and method are provided for rapid and precise manipulation and transfer of tiny liquid droplets. by dynamically introducing microstructures with relatively high surface energy to a non-wettable surface, which surface has in-situ switchable adhesion to liquid droplets. By penetrating microstructures on the background surface, the chemical property of the surface is locally modified. Capillary bridges will form between microstructures and liquid droplets which lead to high adhesive forces. When the microstructures are retracted, the capillary bridges either pinch-off or recede, which drastically reduces the adhesion. With proper chemical modification, the surface can either manipulate a liquid droplet in air or in an immiscible carrier liquid. Tiny droplets with volumes down to nanoliter scale can be prepared and dispensed by using the surface.

Abstract: Feedback is collected from a user during log-on to a system. The feedback from the user can be used to enhance a knowledge base. The feedback is required from the user in order for the user to gain access to the system.

Abstract: An approach is provided for searching multilingual documents. Structure components are extracted from multilingual documents. Based on the extracted components, the documents are grouped into classifications including respective sets of documents expressed in different respective natural languages. A natural language in a query is detected. One of the documents is selected based on the document having content indicated by the query and the natural language of the document matching the detected natural language. Structure components of the selected document are extracted. Based on the extracted structure components of the selected document, one of the classifications is identified as including the selected document. Other document(s) in the classification are identified and presented as having content that matches the content of the selected document. The natural language(s) of the other document(s) are each different from the natural language of the selected document.

Abstract: Embodiments disclose a channel decoding method and apparatus, and a distributed decoder. A channel decoding apparatus includes: a decoding information acquiring unit, configured to acquire demodulation information of a channel; a channel decoding algorithm unit, configured to decode the demodulation information to obtain current decoding information, and perform a cyclic redundancy check CRC check on the current decoding information to obtain a current decoding CRC check result; and a lower level decoding determining unit, configured to: if the current decoding CRC check result is incorrect and a lower level channel decoding apparatus exists, determine that the lower level channel decoding apparatus continues to decode the demodulation information, where decoding performance of a channel decoding algorithm unit in the lower level channel decoding apparatus is superior to decoding performance of the channel decoding algorithm unit in the channel decoding apparatus.

Abstract: Provided is a use of one or more MicroRNA genes selected from miRNAs of Family Let-7, miR-21 or miR-222 in the construction of tissue engineered nerves and in the repair of peripheral nerve defects. An outer and/or internal surface or pores of a tissue engineered nerve graft are coated or adsorbed with polymeric nanomicrospheres carrying a Let-7 family miRNA inhibitor, miR-21, or miR-222, or a mimetic thereof, wherein the polymeric material is composed of biocompatible fibronectin and heparin. The regeneration of peripheral nerves and the construction of tissue engineered nerves are promoted by regulating the expression of MicroRNA genes which can effectively promote the proliferation of primary Schwann cells cultured in vitro and have an anti-apoptotic effect on neuronal cells. In-vivo test proves that bridging of the tissue engineered nerve graft can facilitate the regeneration of peripheral nerves, thus being useful in the treatment of peripheral nerve injury.

Abstract: Embodiments of the present invention provide a method and an apparatus for scheduling a voice service in a packet domain. The method includes: obtaining at least one value of a first scheduling parameter corresponding to each protocol sublayer of L2 of a voice service, determining a condition needing to be satisfied by quality of service of the voice service, determining a value of a service scheduling parameter of the voice service based on the condition needing to be satisfied by the quality of service of the voice service and based on the at least one value of the first scheduling parameter, and scheduling the voice service based on the value of the service scheduling parameter of the voice service. In this way, a service scheduling parameter is adjusted at an appropriate time when a particular condition is satisfied, so that transmission quality of a link can be ensured.

Abstract: A skin surface indwelling device for guiding punctures includes: an indwelling tube (13) having an inside tunnel (P) substantially extending along the longitudinal direction of the indwelling tube (13), the tunnel (P) is used for guiding needle (N), the indwelling tube (13) has a proximal end positioned above the skin surface (S) and a distal end positioned under the skin surface (S) in indwelling state; a support (11) having a bottom surface on its bottom that directly or indirectly contacts with the skin surface (S), the support (11) supports and fixates the indwelling tube (13); and a sealing elements (141,142) configured to seal the tunnel (P). The skin surface indwelling device for guiding punctures can shorten the time of establishing a puncture tunnel in the buttonhole puncture method, and help to build the puncture tunnel. In addition, the skin surface indwelling device can also guide the puncture needle (N) when puncturing, and protect the immature puncture tunnel.

Abstract: A computer-implemented method for cache memory management in a distributed computing environment includes tracking, via a cache balancing engine, a plurality of vehicles operating in a first region. The method further includes executing, via the cache balancing engine, an analysis for a subset of the plurality of vehicles in the first region to determine a weighted mean velocity for each vehicle in the subset of the plurality of vehicles in the first region. The method further includes determining, via the cache balancing engine, based on the analysis, whether a second regional server tracking a second plurality of vehicles in a second region is likely to have an unbalanced cache memory, and rebalancing, via the cache balancing engine, cache memory data in the first regional server and cache memory data in the second regional server responsive to determining that the second regional server is likely to have an unbalanced cache memory.

Abstract: A power control method, apparatus, and system is described. First outer loop power control is performed according to an actual hard metric and a preset target hard metric to adjust a target soft metric required by second outer loop power control, to obtain an adjusted target soft metric. Therefore, this ensures that when the adjusted target soft metric is converged, the target hard metric can be correctly converged to achieve target quality required by a system.

Abstract: It relates to a Mortierella alpine ATCC32222 uracil auxotroph strain and a construction method thereof. In the present invention, Mortierella alpine ATCC32222 is used as a material and undergoes gene knockout through an Agrobacterium tumefaciens mediated genetic manipulation technology, to obtain the Mortierella alpine uracil auxotroph. The method is of great significance for the basic theoretic researches of the oil producing fungus Mortierella alpine ATCC32222 and product development.

Abstract: A computer-implemented method for cache memory management in a distributed computing environment includes tracking, via a cache balancing engine, a plurality of vehicles operating in a first region. The method further includes executing, via the cache balancing engine, an analysis for a subset of the plurality of vehicles in the first region to determine a weighted mean velocity for each vehicle in the subset of the plurality of vehicles in the first region. The method further includes determining, via the cache balancing engine, based on the analysis, whether a second regional server tracking a second plurality of vehicles in a second region is likely to have an unbalanced cache memory, and rebalancing, via the cache balancing engine, cache memory data in the first regional server and cache memory data in the second regional server responsive to determining that the second regional server is likely to have an unbalanced cache memory.

Abstract: Embodiments of the present invention disclose a voice quality assessment method and apparatus. The method includes: obtaining a first transmission error code parameter and a second transmission error code parameter, where the first transmission error code parameter is a transmission error code parameter of an uplink channel of first user equipment, and the second transmission error code parameter is a transmission error code parameter of a downlink channel of second user equipment; and generating an end-to-end voice quality index between the first user equipment and the second user equipment according to the first transmission error code parameter and the second transmission error code parameter.

Abstract: Provided is a method of batching and scheduling for steelmaking production with plant-wide process consideration, including the steps of: establishing a mathematical model for quantitatively describing the decision problem of batching on steelmaking and continuous casting procedures; starting from the production capacity balance between parallel equipment of the same procedure, and material flow convergence between upstream and downstream procedures, establishing a model for the assignment and sequencing of batches on continuous casting equipment and the time dimension; integrating the batching plan and the production scheduling scheme, issuing the batching plan and the production scheduling scheme integrated to all production and manufacturing units at the steelmaking stage.

Abstract: An apparatus and method are provided for rapid and precise manipulation and transfer of tiny liquid droplets. by dynamically introducing microstructures with relatively high surface energy to a non-wettable surface, which surface has in-situ switchable adhesion to liquid droplets. By penetrating microstructures on the background surface, the chemical property of the surface is locally modified. Capillary bridges will form between microstructures and liquid droplets which lead to high adhesive forces. When the microstructures are retracted, the capillary bridges either pinch-off or recede, which drastically reduces the adhesion. With proper chemical modification, the surface can either manipulate a liquid droplet in air or in an immiscible carrier liquid. Tiny droplets with volumes down to nanoliter scale can be prepared and dispensed by using the surface.

Abstract: Disclosed are systems and methods for implementing contract-based polymorphic and parallelizable user-defined scalar and aggregate functions. The systems and methods can include receiving a query including a plurality of user-defined functions, parsing the query into a plurality of nodes (e.g., basic operation unit or atomic operator), generating an execution plan that minimizes data transfer between the plurality of nodes, and executing the plan in a distributed environment. Each of the plurality of user-defined functions can correspond to one of a plurality of nodes.