Publication number: 20230348467
Abstract: The present invention relates to heteroaryl derivatives, preparation methods therefor, and applications thereof in medicine. Specifically, the present invention relates to a heteroaryl derivative represented by general formula (AI), a preparation method therefor, and a pharmaceutically acceptable salt, and use thereof as a therapeutic agent, in particular, as an SHP2 allosteric inhibitor, wherein the definition of substituents in general formula (AI) is the same as that in the description.
Type:
Application
Filed:
January 12, 2021
Publication date:
November 2, 2023
Applicants:
Zhejiang Hisun Pharmaceutical Co., Ltd., Hisun AccuRay Therapeutics Co., Ltd.
Inventors:
Xiangui Huang, Yanghui Guo, Zongxing Qiu, Pingyan Bie, Weiwei Liao, Qingyan Yan, Weichao Shen, Hai Cao, Qingna Xing, Xin Wang, Qi Cao, Lichen Meng, Nuoyi Wu, Wenpeng Li, Cheng Ye, Taishan Hu, Lei Chen