Patents by Inventor Xin Wei Wang

Xin Wei Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for identifying inhibitors of GADD45 polypeptide activity, and inhibitors of such activity
    Patent number: 6613318
    Abstract: The present invention is directed to novel methods for assaying for modulators of GADD45 polypeptide activity. The invention also provides means to sensitize a proliferating cell to a DNA base-damaging agent by administration of novel inhibitors of GADD45 polypeptide activity. The invention further provides polypeptides which interfere with the ability of Cdc2/cyclin B1 complexes to cause a pause at the G2/M stage of the cell cycle in response to GADD45, and nucleic acids which encode such polypeptides.
    Type: Grant
    Filed: March 24, 2000
    Date of Patent: September 2, 2003
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Xin Wei Wang, Curtis C. Harris, Albert J. Fornace, Jr., Jill D. Coursen, Qimin Zhan
  • Screening assays for compounds that cause apoptosis
    Patent number: 6602979
    Abstract: This invention relates to methods of screening for compounds capable of inducing apoptosis in certain tumor cells. The invention also relates to compounds identified by such methods. In addition, the invention relates to methods for the in vitro diagnosis of Xeroderma pigmentosum and compounds useful in these methods.
    Type: Grant
    Filed: December 19, 1994
    Date of Patent: August 5, 2003
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Curtis C. Harris, Xin Wei Wang, Jan H. J. Hoeijmakers
  • Screening assays for compounds that cause apoptosis and related compounds
    Patent number: 5985829
    Abstract: This invention relates to methods of screening for compounds capable of inducing apoptosis in certain tumor cells. The invention also relates to compounds identified by such methods. In addition, the invention relates to methods for the in vitro diagnosis of Xeroderma pigmentosum and compounds useful in these methods.
    Type: Grant
    Filed: July 1, 1996
    Date of Patent: November 16, 1999
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Curtis C. Harris, Xin Wei Wang, Jan H. J. Hoeijmakers