Abstract: Provided are a communication network switching apparatus, a communication network switching system, and a communication network switching method. The apparatus includes a first communication network interface, a second communication network interface, a processor, a communication network switch, and a device access interface. The communication network switch is configured to switch, according to the control signal of the processor, the connection manner with the first communication network interface and the second communication network interface and connect the first communication network or the second communication network to the processor. The processor is connected to the device access interface and is configured to connect a target communication network connected through the communication network switch to a target device connected to the device access interface.

Abstract: Disclosed is a long-distance punching method and device for power generation enterprises, including the following steps: determining the employee geographical position of a target employee according to an employee identification code; calculating the distance value between employee geographical position and enterprise geographical position, and generating a long-distance punching strategy according to the distance value, demand punching time and demand punching method; calculating the time interval of employee punching time according to the timestamp, and generating the employee punching strategy; extracting a first core punching semantics in the long-distance punching strategy, extracting a second core punching semantics in the employee punching strategy, and calculating a matching value between the first core punching semantics and the second core punching semantics; and performing a feedback and updating of the employee punching strategy to obtain an updated employee punching strategy, and performing a lon

Abstract: A device suspension method and a computing device are provided. In the method, before a device enters a suspended state, memory space occupied by a background process that is unrelated to a foreground process is released. In this way, the background process unrelated to the foreground process is not saved in a memory of the device. In other words, it reduces data stored in the memory when the device is suspended. Therefore, when the device needs to be woken up, only a relatively small amount of data needs to be read from the memory, and a working state can be rapidly restored. This can reduce a delay of reading data from the memory when the device is woken up, thereby accelerating a wakeup speed of the device. In addition, the data is stored in the memory when the device is suspended.

Abstract: The present invention is directed to certain 2-aminoquinzaoline derivatives of Formula (I): Formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, and R3 are as defined herein, which are potent inhibitors of LRRK2 kinase and may be useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease and other diseases and disorders described herein. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which LRRK-2 kinase is involved.

Abstract: Described herein are compounds of Formula I or a pharmaceutically acceptable salt thereof wherein A, E, U, X, Y, Z, R1, R2 and n are as defined herein. The compounds of Formula I act as IL4I1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for IL4I1-related diseases. Also provided herein are pharmaceutical compositions comprising the compounds of the invention, or their pharmaceutically acceptable salts, and a pharmaceutically acceptable carrier and methods of treatment with the compounds of the invention.

Abstract: The invention discloses a synthesizing method of benzimidazole derivant and intermediate, which is characterized by the following: proceeding arylation among aryl halide and primary amine; adopting L-pro as additive, cuprous iodide as catalyst; proceeding molecular arylation coupling reaction for aryl iodide or aryl bromide and primary amine; adopting iodo phenylamine compound and bromophenylamine compound as starting material; synthesizing the material through several-step transformation.

Abstract: Techniques are disclosed for dynamically adjusting a throttling threshold in a multi-tenant virtualized computing environment. System health parameters are collected during a predetermined time interval. A system health status of the multi-tenant virtualized computing environment is determined. Based on the system health status, a throttling threshold for service requests for the multi-tenant virtualized computing environment is determined. The throttling threshold is applied for further service requests. During a subsequent time interval, an updated system health status of the multi-tenant virtualized computing environment is determined based on system health parameters received during the subsequent time interval. The throttling threshold is updated based on the updated system health status. The updated throttling threshold is applied for further service requests.

Abstract: The present disclosure provides compositions comprising novel mass tags. The disclosure also provides methods utilizing mass tags, including methods of quantifying one or more individual lipids from a composition of lipids, methods of identifying a double bond position of an individual lipid, methods of identifying a biological correlation of an individual lipid, and methods of preparing a lipid derivative.

Abstract: The present invention is directed to substituted certain N-heteroaryl indazole derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, X, Y, and Z are as defined herein, which are potent inhibitors of LRRK2 kinase and may be useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease and other diseases and disorders described herein. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of diseases, such as Parkinson's disease, in which LRRK-2 kinase is involved.

Abstract: The present invention relates to a cell gel preparation, which is used for treating and/or preventing acute or chronic osteoarthritis and/or symptoms thereof by means of intra-articular injection, wherein the preparation comprises a nucleic acid hydrogel loading mesenchymal stem cells. The present invention further relates to a method for treating or preventing acute and chronic osteoarthrosis and associated symptoms caused by inflammation (especially osteoarticular pain and activity or function loss) by means of using the cell gel preparation, and a method for reducing the shear damage on cells in a shear environment by means of using the nucleic acid hydrogel.

Abstract: Examples of simulated powdered model generation for neural networks are described herein. In some examples, a set of simulated powdered models that simulate application of powder to a computer aided design (CAD) model are generated. In some examples, synthetic images of the simulated powdered models placed in a virtual environment are generated. In some examples, a neural network is trained to recognize real objects based on the synthetic images of the simulated powdered models.

Abstract: The method and system disclosed herein present a cooking tutorial program that provides intelligent assistance to users during meal preparation, the method and system comprise: receiving a user selection of a recipe; playing a first content item corresponding to a first preparation step of the selected recipe in a first media format; monitoring user's actions performing the first preparation step of the selected recipe; and if the user's actions performing the first preparation step meet first criteria, adjusting the playing of the first content item, including displaying the first content item in a second media format, wherein the second media format differ from the first media format in at least a size and resolution of a portion of the first content item.

Abstract: The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface.

Abstract: A gimbal includes an axis structure including a rotating member, a bearing member rotatably connected to the rotating member, and a locking structure. The rotating member includes a rotor of a motor or a member fixedly connected to a rotor. The bearing member includes a stator of the motor or a member fixedly connected to a stator. The locking structure includes a positioning snap member movably provided on one of the rotating member and the bearing member and configured to engage with another one of the rotating member and the bearing member. The axis structure is a yaw-axis structure, a roll-axis structure or a pitch-axis structure. The motor is configured to control a movement about a pitch axis, a movement about a yaw axis, or a movement about a roll axis. A rotational position of the rotating member relative to the bearing member is locked by the locking structure when the rotating member rotates to a preset position.

Abstract: The present invention is directed to certain 2-aminoquinzaoline derivatives of Formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, and R3 are as defined herein, which are potent inhibitors of LRRK2 kinase and may be useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease and other diseases and disorders described herein. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which LRRK-2 kinase is involved.

Abstract: Embodiments of this application provide a storage component, a preparation method, a reading/writing method, a storage chip, and an electronic device, is related to the storage technology field, and is used to resolve a problem that a quantity of storage states of a spin orbit torque-magnetic random access memory is increased while a storage state change range remains unchanged. The storage component includes: a first magnetic tunnel junction, a spin orbit coupling layer and a second magnetic tunnel junction that are sequentially arranged in a stacked manner. The first magnetic tunnel junction includes a first free layer, and the second magnetic tunnel junction includes a second free layer. The first free layer and the second free layer are arranged on two opposite surfaces of the spin orbit coupling layer.

Abstract: Methods for identifying a structural feature of a lipid include: (a) conducting at least one voltage-controlled electrochemical reaction that converts the lipid to a first derivatized lipid; and (b) fragmenting the first derivatized lipid to generate at least one diagnostic ion indicative of a first structural feature of the lipid.

Abstract: The present invention is directed to certain 2-aminoquinzaoline derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R3, R4, X1, and X2 are as defined herein, which are potent inhibitors of LRRK2 kinase and may be useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease and other diseases and disorders described herein. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which LRRK-2 kinase is involved.