Abstract: A strain and acoustic wave testing device includes an acoustic wave transmitting terminal, an upper pressure-bearing shaft, corundum ejector pins, an upper displacement slide, a lower displacement slide, a heat insulation shell, a carbon fiber sleeve, a rock sample, a lower pressure-bearing shaft, an acoustic wave receiving terminal, a lower copper electrode, pearl powder, a temperature sensor, a transformer, a temperature-acoustic wave control box, an oscilloscope, an upper copper electrode, and a data collection and processing system.

Abstract: The present invention relates to compositions and methods of using those compositions for the diagnosis and treatment of immune related diseases.

Abstract: A Doherty power amplifier having a main power amplification device and an auxiliary power amplification device arranged in parallel with the main power amplification device includes a load modulation circuit having a harmonic injection circuit connected with respective outputs of the main power amplification device and the auxiliary power amplification device. The harmonic injection circuit is arranged to provide a phase shift to simultaneously modulate transfer of second harmonic components generated at the main power amplification device to the auxiliary power amplification device and transfer of second harmonic components generated at the auxiliary power amplification device to the main power amplification device, when the main power amplification device and the auxiliary power amplification device are operated at saturation.

Abstract: A hearing protection method, an apparatus and a system are provided. the start command input by the user is received by the hearing protection apparatus to activate the hearing protection mode; the sound data in multiple dimensions is collected and whether the sound data in any of the dimensions is within a corresponding preset threshold is determined; and corresponding prompt information is sent when the sound data in any of the dimensions exceeds the corresponding preset threshold Thus, various prompting manners are provided to remind the user to make corresponding adjustments, thereby achieving the purpose of hearing protection, and effectively adapting to the needs of specific users.

Abstract: A seal case for a bearing seal includes (a) an inner case encircling a rotation axis of the bearing seal, (b) an outer case encircling the rotation axis and including a ring-shaped frame and a rubber gasket over-molded on the frame, and (c) a plastic wafer clamped between the inner case and the outer case, and secured at least by the rubber gasket. A method for manufacturing a bearing seal includes over-molding a rubber gasket onto a ring-shaped frame to form an outer case, placing a plastic wafer between the rubber gasket and an inner case, and securing the inner case to the outer case to form a seal case.

Abstract: The instant technology relates to a production system to produce AAV vectors in a serum free suspension platform and at high titers. This technology uses reagents comprising media, cells, transfection reagent, AAV enhancer, and a lysis buffer, each of which is designed to provide maximal AAV production from suspension culture of mammalian cells, e.g. HEK293 cells. With this new system we are able to deliver up to about 2×1011 viral genomes per milliliter (vg/mL) of unconcentrated AAV vectors.

Abstract: Embodiments provide methods and devices for providing object information associated with a media program. Embodiments include identifying an object of interest in an image of a frame of the media program; inserting an indicator into the image of the frame to identify the object of interest; generating a video clip associated with the identified object based on a portion of the media program; constructing an information page containing information regarding the object of interest, wherein the information page comprises a window for displaying the video clip; and transmitting the information page, including the video clip, to the user device.

Abstract: Methods and apparatus for subtractively fabricating three-dimensional structures relative to a surface of a substrate and for additively depositing metal and dopant atoms onto the surface and for diffusing them into the bulk. A chemical solution is applied to the surface of the semiconductor substrate, and a spatial pattern of electron-hole pairs is generated by projecting a spatial pattern of illumination characterized by a specified intensity, wavelength and duration at each pixel of a plurality of pixels on the surface. Charge carriers are driven away from the surface of the semiconductor on a timescale short compared to the carrier recombination lifetime. Such methods are applied to creating a spatially varying doping profile in the semiconductor substrate, a photonic integrated circuit and an integrated photonic microfluidic circuit.

Abstract: The invention provides complexes of Zn2+ of formulae (la) and (IIa) that are useful for treating cancer, as well as compositions and kits comprising such complexes.

Abstract: The disclosure relates to a method for using fuel cell. The fuel cell includes a container, wherein the container comprises a housing and a nozzle, and the housing defines through holes; the housing defines a chamber and an opening; the nozzle has a first end in air/fluid communication with the opening and a second end; and a membrane electrode assembly, which is flexible, on the container to form a curved membrane electrode assembly surrounding the chamber and covering the through holes, wherein the membrane electrode assembly comprises a proton exchange membrane having a first surface and a second surface, a cathode electrode on the first surface and an anode electrode on the second surface. The method includes at least partially immersing the fuel cell in a fuel; and supplying an oxidizing gas into the chamber.

Abstract: A melting pot includes a pot body and a float salvaging apparatus. The pot body is provided with a melting chamber having an open upper end. The float salvaging apparatus includes a hanging bracket, a bearing plate, a rotating plate and a drive assembly configured to drive pivoting of the rotating plate. The hanging bracket is disposed above the melting chamber. The rotating plate is pivotably disposed on the bearing plate, and the bearing plate and the rotating plate are provided on the hanging bracket between an initial position and a first salvaging position in a manner of moving up and down. The drive assembly is connected to the rotating plate.

Abstract: A vehicle system virtualizing add-on device hardware for a vehicle application. The system includes a computer-readable storage device comprising a client application, middleware components, kernel-space components, and a vehicle application. The client application communicates with an add-on-device server application for virtualizing the add-on-device hardware component at the vehicle. The middleware, in various embodiments, includes an emulated system-call application-program-interface module that receives add-on-device-hardware data from the client application, sends the data to the kernel-space components after processing, and receives the data having been processed at the kernel space. The middleware includes a frameworks-and-abstraction module that receives add-on-device-hardware data, having been processed at the kernel space and the emulated system-call-application-program-interface module and after processing sends the data for use at the vehicle application.

Abstract: The present invention describes combination treatment comprising a PD-1 axis binding antagonist and an agent that decreases or inhibits TIGIT expression and/or activity and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer or chronic infection.

Abstract: Vertical-cavity surface-emitting lasers (VCSELs) and methods for making such are provided. The VCSELs include stepped upper reflectors having respective differently-sized apertures. This allows the lower portion of the reflector to have formed therein a wider-diameter aperture to allow for increased current injection. The upper portion of the reflector has formed therein a narrower-diameter, mode-selecting aperture to allow higher-order modes to be reduced, leading to single-mode operation. The VCSELs are thus capable of higher-power emission in a single mode, allowing for longer-distance signaling over optical fiber, despite modal dispersion within the fiber and/or at the coupling between the VCSEL and the fiber. The two differently-sized apertures can be formed via respective lateral oxidation processes following etch-down to form the respective steps of the upper reflector.

Abstract: The present invention describes combination treatment comprising a PD-1 axis binding antagonist and an agent that decreases or inhibits TIGIT expression and/or activity and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer or chronic infection.

Abstract: A bearing seal includes a seal case, a sleeve, and a thrust bumper disposed between the seal case and the sleeve to define spacing between the seal case and the sleeve during assembly of a wheel end implementing the bearing seal. The thrust bumper includes polytetrafluoroethylene.

Abstract: The invention provides compounds of formula I and II and salts thereof, wherein R1, R2, Y, R3, and R4 have any of the meanings described in the specification, as well as compositions comprising such compounds and salts, and methods for treating cancer using such compounds and salts.

Abstract: The invention provides organic complexes of Zn2+ that are useful for treating cancer, as well as compositions and kits comprising such complexes, and intermediate monomer compounds that are useful for the preparation of such complexes.

Abstract: The invention relates to a device for a radio communications system, the device including: a processing unit; a memory unit; and a transceiver including a transmitter provided with a power amplifier; wherein said device is configurable to: send a request to a base station of said communications system for permission of transmission of one or more data symbols, the one or more data symbols being amplified with the power amplifier in an overdrive regime; receive a grant for such transmission; amplify the one or more data symbols with the power amplifier of the transmitter in the overdrive regime; and transmit the one or more data symbols to the base station.