Abstract: The present invention is related to a self-assembled nanoparticle containing a gB protein of an EB virus and a preparation method and use thereof. The self-assembled nanoparticle comprises a first polypeptide and a second polypeptide; the first polypeptide comprises the gB protein and a first vector subunit, the second polypeptide comprises a second vector subunit; the first vector subunit is I53-50A1, and the second vector subunit is I53-50B.4PT1. In the self-assembled nanoparticle, the gB protein of the EB virus is displayed on the surface of the nanoparticle for the first time. The particle size of the self-assembled nanoparticle is larger than that of the antigen gB, and the chemical stability of the self-assembled nanoparticle is higher than that of the antigen gB, and the binding capacity with the neutralizing antibody of the self-assembled nanoparticle are higher than that of the antigen gB.

Abstract: A gear slicing tool and a manufacture method thereof are provided. The gear slicing tool includes a gear slicing tool body having concave and/or convex parts formed on a tool surface of the gear slicing tool body and a composite film layer disposed on the tool surface. The composite film layer includes a metal film layer, a transition film layer, and a functional film layer. A material of the metal film layer includes a metal. The transition film layer includes a first film layer and a second film layer. A material of the first film layer includes a nitride of the metal. A material of the second film layer includes a nitride of an alloy of the metal and aluminum. A material of the functional film layer includes a nitride of an alloy of the metal, aluminum, and silicon.

Abstract: Disclosed is a preparation method of a dual-network collagen-based supramolecular hydrogel, including: preparing a silicate nanosheet dispersion and a collagen solution separately; mixing the silicate nanosheet dispersion with the collagen solution followed by stirring to obtain a collagen-silicate nanosheet network; preparing a tannic acid solution and a polyethylene glycol solution separately; mixing the tannic acid solution with the polyethylene glycol solution to obtain a polyethylene glycol-tannic acid network; and subjecting the collagen-silicate nanosheet network and the polyethylene glycol-tannic acid network to reaction to obtain the dual-network collagen-based supramolecular hydrogel. A dual-network collagen-based supramolecular hydrogel prepared by such method is also provided.

Abstract: Disclosed are a self-assembled nanoparticle containing a gB protein of an EB virus and a preparation method and use thereof The self-assembled nanoparticle comprises a first polypeptide and a second polypeptide; the first polypeptide comprises the gB protein and a first vector subunit, the second polypeptide comprises a second vector subunit; the first vector subunit is I53-50A1, and the second vector subunit is I53-50B.4PT1. In the self-assembled nanoparticle provided herein, the gB protein of the EB virus is displayed on the surface of the nanoparticle for the first time. The particle size of the self-assembled nanoparticle is larger than that of the antigen gB, and the chemical stability of the self-assembled nanoparticle is higher than that of the antigen gB, and the binding capacity with the neutralizing antibody of the self-assembled nanoparticle are higher than that of the antigen gB.

Abstract: A device for detecting the elongation of a hydraulic cylinder includes an electric signal conversion device, a ruler and a positional magnetic ring. The electric signal conversion device is disposed at the bottom of a cylinder barrel. The ruler has an end fixedly connected to the electric signal conversion device, as well as the other end movably extending into a piston rod. The positional magnetic ring is fixedly connected to a piston and the positional magnetic is movably disposed around the periphery of the ruler. When the positional magnetic ring is located at different positions of the ruler, different circuits are turned on to transmit a voltage or current signal corresponding to the positions of the ruler to the electric signal conversion device, so as to obtain a position of the positional magnetic ring on the ruler, such that the elongation of the piston rod is obtained.

Abstract: Disclosed is a preparation method of a dual-network collagen-based supramolecular hydrogel, including: preparing a silicate nanosheet dispersion and a collagen solution separately; mixing the silicate nanosheet dispersion with the collagen solution followed by stirring to obtain a collagen-silicate nanosheet network; preparing a tannic acid solution and a polyethylene glycol solution separately; mixing the tannic acid solution with the polyethylene glycol solution to obtain a polyethylene glycol-tannic acid network; and subjecting the collagen-silicate nanosheet network and the polyethylene glycol-tannic acid network to reaction to obtain the dual-network collagen-based supramolecular hydrogel. A dual-network collagen-based supramolecular hydrogel prepared by such method is also provided.

Abstract: Disclosed is a method for preparing 2,2?-dipyridine and derivatives thereof. The method includes: using pyridine represented by formula I or a derivative thereof as a raw material to generate 2,2?-dipyridine represented by formula II by performing dehydrogenative coupling under the action of a supported catalyst in the presence of additives, where R is H, C1-C2 alkyl, Cl, or Br. The method of the present invention features wide adaptability to raw materials, high atomic utilization rate, high catalyst activity, long service life, and fewer by-products.

Abstract: A method for preparing 1,1?-ethylene-2,2?-bipyridinium dichloride includes mixing an aqueous diquat dibromide solution with hydrochloric acid, adding dropwise to a mixture of an organic solvent, a bromine absorbent, and an oxidant, and reacting to produce 1,1?-ethylene-2,2?-bipyridinium dichloride.

Abstract: Disclosed is a method for preparing 2,2?-dipyridine and derivatives thereof. The method includes: using pyridine represented by formula I or a derivative thereof as a raw material to generate 2,2?-dipyridine represented by formula II by performing dehydrogenative coupling under the action of a supported catalyst in the presence of additives, where R is H, C1-C2 alkyl, Cl, or Br. The method of the present invention features wide adaptability to raw materials, high atomic utilization rate, high catalyst activity, long service life, and fewer by-products.

Abstract: A method for preparing 1,1?-ethylene-2,2?-bipyridinium dichloride includes mixing an aqueous diquat dibromide solution with hydrochloric acid, adding dropwise to a mixture of an organic solvent, a bromine absorbent, and an oxidant, and reacting to produce 1,1?-ethylene-2,2?-bipyridinium dichloride.

Abstract: Disclosed is a method for the detection of virus variations. Disclosed also is a method for the treatment of virus infection in a subject based on the detection of virus variations. Additionally, a kit is provided for the detection of virus variations.

Abstract: Disclosed is a method for the detection of virus variations. Disclosed also is a method for the treatment of virus infection in a subject based on the detection of virus variations. Additionally, a kit is provided for the detection of virus variations.