Patents by Inventor Xing C. Cheng

Xing C. Cheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Halimide, a cytotoxic marine natural product, and derivatives thereof
    Patent number: 6069146
    Abstract: The present invention provides a substantially purified compound having the structure: ##STR1## wherein R.sub.1 to R.sub.9 are defined; or a salt of the compound, and provides pharmaceutical compositions comprising a compound of the invention and a pharmaceutically acceptable carrier. The invention also provides methods of reducing or inhibiting mitosis of a cell by contacting the cell with a compound of the invention, which blocks the cell at the G2/M phase of the cell cycle. The invention also provides a method of reducing the severity of a pathology characterized, at least in part, by undesirable proliferation of a population of cells in a subject by administering to the subject a compound of the invention in an amount sufficient to reduce or inhibit proliferation of the population of cells.
    Type: Grant
    Filed: November 12, 1998
    Date of Patent: May 30, 2000
    Assignee: The Regents of the University of California
    Inventors: William Fenical, Paul R. Jensen, Xing C. Cheng
  • Avrainvillamide, a cytotoxic marine natural product, and derivatives thereof
    Patent number: 6066635
    Abstract: The present invention provides a compound having the structure ##STR1## wherein, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are independently selected from H, alkyl, aminoalkyl, perfluoroalkyl, orpharmaceutically acceptable salts thereof, useful for treating cancer.
    Type: Grant
    Filed: March 23, 1999
    Date of Patent: May 23, 2000
    Assignee: University of California, San Diego
    Inventors: William Fenical, Paul R. Jensen, Xing C. Cheng