Abstract: Provided herein are novel compounds, for example, compounds having a Formula (I), or a pharmaceutically acceptable N salt thereof. Also provided herein are methods of preparing the compounds and methods of using the compounds, for example, in inhibiting TYK2, and/or function of IL-12, IL-23 and/or INF-alpha, and/or in treating various associated diseases or disorders.

Abstract: A main and auxiliary alloy-based neodymium-iron-boron magnet material and the preparation method thereof. The raw material composition for the main and auxiliary alloy-based neodymium-iron-boron magnet material includes a main alloy raw material and an auxiliary alloy raw material, wherein the mass percentage of the auxiliary alloy raw material in the raw material composition for the main and auxiliary alloy-based neodymium-iron-boron magnet material is 1.0-15.0 mass %. For the main and auxiliary alloy-based neodymium-iron-boron magnet material prepared by using the raw material composition, the coercivity is increased while high remanence is ensured, and the preparation method therefor can be suitable for engineering applications.

Abstract: The present disclosure relates to a battery unit and a battery module, the battery unit includes an electrode assembly, including a main body portion and a tab; two electrode terminals; and two current collecting members respectively connecting the tabs on both sides of the main body portion with the respective electrode terminals; the current collecting member includes a guiding plate and a supporting plate, the guiding plate is located on one side of the main body portion along the length direction, a reinforcement portion is arranged on the guiding plate and is configured to reduce the deformation of the guiding plate towards the main body portion; and the supporting plate is connected to an end of the guiding plate along the width direction, the tab is bent relative to the length direction and connected to the supporting plate. The battery unit can reduce the bending deformation of the guiding plate.

Abstract: Mechanisms are provided for scheduling a workload in a cloud computing system. A cloud affinity factor (CAF) computer model is trained, via a machine learning process based on a training dataset comprising static characteristics of a workload binary for a workload, and dynamic characteristics corresponding to historical performance data for the workload, such that the trained CAF computer model predicts a performance classification for a given workload binary. The trained CAF computer model processes a new workload to generate a performance classification for the new workload. Cloud affinity factor(s) are generated based on the performance classification for the new workload. Node affinity and dispatch rule(s) are applied to the cloud affinity factor(s) to select one or more nodes of the cloud computing system to which to dispatch the workload. The workload is then scheduled on the selected one or more nodes.

Abstract: In an embodiment, an apparatus (100) is described. The apparatus comprises an infrared, IR, generating system (102). The IR generating system comprises a first IR source (104) configured to produce IR radiation for forming a first IR beam (106) in a first spectral band. The IR generating system further comprises a second IR source (108) configured to produce IR radiation for forming a second IR beam (110) in a second spectral band. The apparatus further comprises a beam manipulation system (112) configured to combine a beam path of the first and second IR beams and direct the first and second IR beams along the beam path through a gas sample region (114). The apparatus further comprises an IR detection system (116) configured to detect an intensity of the first and second IR beams after passage through the gas sample region. The IR detection system is configured to produce a signal (118) from which an indication of a concentration of a target gas in the gas sample region can be derived.

Abstract: A sander including a housing, a motor housed in the housing and a platen which is driven by the motor. The sander also includes a dust chute, a dust container and a one-way valve disposed in the dust chute. The one-way valve allows air to flow in a direction towards the dust container and limits the flow of air in a direction away from the dust container. The one-way valve allows air flow in the direction towards the dust containers through multiple different openings.

Abstract: The present invention relates to a DoxA protein mutant having an amino acid sequence set forth in SEQ ID NO: 16, and coding gene thereof. The protein mutant or the coding gene thereof can be used for producing epirubicin. The present invention further relates to a Streptomyces capable of efficiently expressing epirubicin, which is constructed by replacing the dnmV gene of a starting Streptomyces in situ with the avrE gene and mutating the doxA gene of the starting Streptomyces into a gene encoding the protein set forth in SEQ ID NO: 16. The fermentation broth of this Streptomyces has an epirubicin potency of up to 102.0 ?g/ml.

Abstract: A capnometer (10) includes an integrated device (30, 30A, 30B) comprising a substrate (40), a lead selenide (PbSe) layer (42) or other infrared light absorbing layer disposed on the substrate, and a bandpass filter layer (50) disposed on the substrate. A temperature sensor tracks temperature of the device. A CO2 measurement cell (20) has light source (28) arranged to emit light (L) that passes through a flow path (F) and then through the bandpass filter layer of to reach the PbSe or other infrared light absorbing layer. Electronics (32) connected with the PbSe or other infrared light absorbing layer measure a photoconductivity signal. The electronics includes signal processing circuitry to convert the photoconductivity signal to a carbon dioxide partial pressure or concentration value. The electronics also includes the temperature sensor to enable accurate and fast temperature control of the device and instant temperature compensation for the temperature change.

Abstract: An infrared emitter is formed having a reduced thermal mass and increased thermal conductivity to effectively deliver and dissipate heat from a heating element that emits electromagnetic radiation. The improved thermal dynamic process may enhance one or both of power consumption and/or longevity.

Abstract: The present invention relates to a DoxA protein mutant having an amino acid sequence set forth in SEQ ID No. 16, and coding gene thereof. The protein mutant or the coding gene thereof can be used for producing epirubicin. The present invention further relates to a Streptomyces capable of efficiently expressing epirubicin, which is constructed by replacing the dnmV gene of a starting Streptomyces in situ with the avrE gene and mutating the doxA gene of the starting Streptomyces into a gene encoding the protein set forth in SEQ ID No. 16. The fermentation broth of this Streptomyces has an epirubicin potency of up to 102.0 ?g/ml.

Abstract: An infrared detector includes a radiation source configured to emit electromagnetic radiation. The detector includes a source monitoring apparatus configured to generate output signals (62) related to electrical resistance through the radiation source. The output signals are used to account for radiation source temperature in measurements by the detector. The output signals may be used (72) in the provision of power to the radiation source to maintain the temperature of the detector at a beneficial level. The detector is configured to monitor a level of a gaseous molecular species within a flow of breathable gas.

Abstract: A gas measurement detector includes first and second sources emitting mid- and near-infrared electromagnetic radiation respectively; source optics combining mid- and near-infrared electromagnetic radiation emitted by the first and second sources into a coaxial beam directed across a flow path of a flow of breathable gas; sensor optics dividing electromagnetic radiation in the coaxial beam that has traversed the flow path into first radiation that includes mid-infrared electromagnetic radiation and second radiation that includes near-infrared electromagnetic radiation; first and second radiation sensors generating output signals conveying information related to a parameter of the mid-infrared electromagnetic radiation in the first radiation and a parameter of the near-infrared electromagnetic radiation in the second radiation, respectively; and a processor determining a level of a gaseous molecular species based on the output signals with the output signals generated by the second radiation sensor compensating

Abstract: Embodiments of the disclosure provide a method and apparatus for sharing data. The method includes: initiating the data sharing application on a first terminal; inserting the file to be shared in a webpage of the data sharing application on the first terminal, and generating an URL for the file in the data sharing application; the data-sharing application of the first terminal broadcasts the URL to other terminal, so that other terminals can share the file via the URL. The present disclosure can reduce the cost of data sharing while improve on the real-timeliness.

Abstract: Gas measurement detectector configured to monitor a level of a gaseous molecular species within a flow path (18) of a flow of breathable gas that communicates with an airway of a subject is performed by infrared spectroscopy. Rather than using an individual source (20) to generate electromagnetic radiation at reference and measurement wavelengths, a near-infrared electromagnetic radiation source (22) is used to generate reference electromagnetic radiation.

Abstract: An infrared emitter is formed having a reduced thermal mass and increased thermal conductivity to effectively deliver and dissipate heat from a heating element that emits electromagnetic radiation. The improved thermal dynamic process may enhance one or both of power consumption and/or longevity.

Abstract: An information publishing method and apparatus are provided that relate to the communications field and are capable of publishing different information for different wireless local area network (WLAN) hotspots. The information publishing method includes: receiving, by an information publishing server, an information content request message sent by a terminal device, where the information content request message carries a media access control (MAC) address of an access point (AP); obtaining, by the information publishing server according to the MAC address of the AP, information content corresponding to the MAC address of the AP; and sending, by the information publishing server, the information content to the terminal device. The present invention is used for information publishing.

Abstract: Embodiments of the disclosure provide a method and apparatus for sharing data. The method includes: initiating the data sharing application on a first terminal; inserting the file to be shared in a webpage of the data sharing application on the first terminal, and generating an URL for the file in the data sharing application; the data-sharing application of the first terminal broadcasts the URL to other terminal, so that other terminals can share the file via the URL. The present disclosure can reduce the cost of data sharing while improve on the real-timeliness.

Abstract: An infrared detector includes a radiation source configured to emit electromagnetic radiation. The detector includes a source monitoring apparatus configured to generate output signals (62) related to electrical resistance through the radiation source. The output signals are used to account for radiation source temperature in measurements by the detector. The output signals may be used (72) in the provision of power to the radiation source to maintain the temperature of the detector at a beneficial level. The detector is configured to monitor a level of a gaseous molecular species within a flow of breathable gas.

Abstract: Targeted attribute transformation involves obtaining a digital image of the skin, selecting an individual skin attribute (an imperfection, such as a blemishes, pores, or wrinkles), extracting the individual skin attribute from the digital image by linear digital filtering on all the color channels, to obtain a contrast map in all three channels of the individual attribute, and adding or subtracting a fraction of the contrast map to the initial image, to obtain the skin image with transformed selected skin attribute.

Abstract: Disclosed are compounds comprising the structure: In one aspect, the compounds exhibit maximum symmetric branching. Also disclosed are bilayers, micelles, coatings, and nanoparticles comprising the disclosed compounds. Also disclosed are processes for the preparation of the disclosed compounds and methods of using the disclosed compounds. Also disclosed are highly fluorinated dendrons and methods for making same. Also disclosed are methods for Fluorous Mixture Synthesis and tagging. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.