Patents by Inventor XINGDAO HE

XINGDAO HE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240044709
    Abstract: Disclosed is a linear array scanning Brillouin scattering elastic imaging device. In the device, a signal generating system consists of a narrow linewidth continuous wave laser, a half-wave plate, a beam expander, a Y-direction scanning galvanometer, a microlens array, a pinhole array filter, a first plano-convex lens, a polarization beam splitter, a quarter-wave plate and a microscope objective. A signal receiving system consists of a microscope objective, a quarter-wave plate, a polarization beam splitter and an eight-channel optical collimator array. Each channel of an eight-channel spectrometer consists of an optical collimator, a convex lens, a scanning Fabry-Perot interferometer, a photomultiplier tube and an eight-channel photon collection card.
    Type: Application
    Filed: June 27, 2023
    Publication date: February 8, 2024
    Inventors: Jiulin SHI, Jin XU, Tianchi SUN, Liangya CUI, Xin LAN, Mingxuan LIU, Xingdao HE
  • Publication number: 20240032895
    Abstract: Disclosed is a Brillouin-optical coherence-speckle based multi-mode elasticity measurement device, including a Brillouin-optical coherence elastography common-path scanning unit, a Brillouin scattering elastography system, an optical coherence elastography system, a speckle elastography system, and a time sequence controller, where the Brillouin scattering elastography system and the optical coherence elastography system share the Brillouin-optical coherence elastography common-path scanning unit.
    Type: Application
    Filed: January 11, 2023
    Publication date: February 1, 2024
    Applicant: Nanchang Hangkong University
    Inventors: Xingdao He, Jiulin Shi, Yubao Zhang, Zhongqi Hao, Gang Shi, Jin Xu
  • Publication number: 20240035804
    Abstract: Disclosed is a Brillouin-optical coherence tomography angiography (OCTA)-speckle multi-mode elastography system device, including a Brillouin-OCTA sample scanning unit, a Brillouin scattering elastography system, an OCTA system, a speckle detection system, and a time sequence controller. According to the present invention, advantages that the Brillouin scattering elastography system can perform high-resolution measurement on a bulk elasticity modulus, the OCTA system can perform high-resolution structure imaging, and the speckle detection system can perform wide-field blood flow velocity measurement are utilized to perform in-situ synchronous imaging on a blood vessel structure and elasticity distribution, and to quantify a blood flow velocity, so that scientific basis and technical support are provided for early diagnoses of clinical blood vessel diseases.
    Type: Application
    Filed: January 5, 2023
    Publication date: February 1, 2024
    Inventors: Xingdao HE, Jiulin SHI, Yubao ZHANG, Zhongqi HAO, Jin XU, Gang SHI
  • Publication number: 20230381476
    Abstract: The present invention provides an electricity-driven, micro-electroporation based drug delivery system, in particular, an electrically conductive array of microprotrusions containing intended substances or molecules to be delivered, which is to the benefit of a recipient receiving vaccination transcutaneously in the absence of any assistive mechanical or actuation means as in conventional injection methods, so as to lower safety risks, improve immunization efficiency, and also induce immune response of the recipient more effectively at a relatively lower dose of vaccines.
    Type: Application
    Filed: May 26, 2022
    Publication date: November 30, 2023
    Inventors: Peng SHI, Yuan WANG, Jin QU, Kai XIE, Suling DUAN, Xingdao HE
  • Patent number: 11209596
    Abstract: The present invention provides a tapered side-polished fiber-optic biosensor (FOBS) and a method for preparing a tapered side-polished fiber (SPF). The biosensor includes a broadband light source, a first single-mode fiber, a tapered SPF, a second single-mode fiber, and a spectrometer. The broadband light source is connected to the tapered SPF through the first single-mode fiber, and the tapered SPF is connected to the spectrometer through the second single-mode fiber. The broadband light source is configured to emit a light wave. The spectrometer is configured to display a spectrum corresponding to a light wave passing through the first single-mode fiber, the tapered SPF, and the second single-mode fiber successively. In the present invention, a fiber side-polishing technology is combined with a fiber tapering technology to construct a tapered SPF, and a spectrum changes by changing a refractive index around a side-polished tapered region, thereby measuring the refractive index.
    Type: Grant
    Filed: June 23, 2020
    Date of Patent: December 28, 2021
    Assignee: NANCHANG HANGKONG UNIVERSITY
    Inventors: Bin Liu, Wei Luo, Qiang Wu, Juan Liu, Shengpeng Wan, Xingdao He
  • Publication number: 20210181420
    Abstract: The present invention provides a tapered side-polished fiber-optic biosensor (FOBS) and a method for preparing a tapered side-polished fiber (SPF). The biosensor includes a broadband light source, a first single-mode fiber, a tapered SPF, a second single-mode fiber, and a spectrometer. The broadband light source is connected to the tapered SPF through the first single-mode fiber, and the tapered SPF is connected to the spectrometer through the second single-mode fiber. The broadband light source is configured to emit a light wave. The spectrometer is configured to display a spectrum corresponding to a light wave passing through the first single-mode fiber, the tapered SPF, and the second single-mode fiber successively. In the present invention, a fiber side-polishing technology is combined with a fiber tapering technology to construct a tapered SPF, and a spectrum changes by changing a refractive index around a side-polished tapered region, thereby measuring the refractive index.
    Type: Application
    Filed: June 23, 2020
    Publication date: June 17, 2021
    Inventors: BIN LIU, WEI LUO, QIANG WU, JUAN LIU, SHENGPENG WAN, XINGDAO HE