Patents by Inventor Xingguo Liu
Xingguo Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12228970Abstract: Provided is a flexible display structure, including a reinforcing strip, and a flexible display panel and a supporting layer that are laminated. The flexible display panel is provided with a first surface and a second surface opposite to each other, and a first side surface connecting the first surface and the second surface, and the reinforcing strip is disposed on the first side surface and configured to adhere the flexible display panel to the supporting layer.Type: GrantFiled: March 10, 2021Date of Patent: February 18, 2025Assignees: CHENGDU BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.Inventors: Shaokui Liu, Wei Qing, Qiang Tang, Zhihui Wang, Xingguo Liu, Xianlei Bi
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Publication number: 20250034135Abstract: Disclosed is a BCL-2 protein apoptosis inducer, and further disclosed are the uses of the compound and a pharmaceutical composition comprising the compound in the preparation of a drug for treating diseases related to anti-apoptotic protein BCL-2. The compound has potent BCL-2/BAK blocking activity, and can be used for treating diseases such as infectious diseases, immune diseases, inflammatory diseases or cell proliferation abnormalities that benefit from the inhibition of anti-apoptotic protein BCL-2.Type: ApplicationFiled: December 6, 2022Publication date: January 30, 2025Inventors: Xingguo LIU, Mingbo SU, Yizhe WU, Anhui GAO, Xinglu ZHOU, Li ZHONG, Miao HU, Jinglai HUANG, Hanghui JING, Jianrong ZHU
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Publication number: 20240431056Abstract: Provided are a flexible display structure. The flexible display structure includes a reinforcing strip, and a flexible display panel and a transparent cover plate that are laminated, wherein the transparent cover plate is provided with a fifth surface and a sixth surface opposite to each other, and a third side surface connecting the fifth surface to the sixth surface; and the flexible display panel is adhered to the transparent cover plate via an optical adhesive layer, and the reinforcing strip is disposed at least on the third side surface.Type: ApplicationFiled: September 6, 2024Publication date: December 26, 2024Inventors: Shaokui LIU, Wei QING, Qiang TANG, Zhihui WANG, Xingguo LIU, Xianlei BI
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Patent number: 12171135Abstract: Provided is a foldable display. The foldable display includes a rigid substrate, a bonding layer, and a flexible display panel which are sequentially stacked; wherein the rigid substrate includes a first substrate area and a second substrate area, the second substrate area being foldable; and the bonding layer includes a first bonding area and a second bonding area, the first bonding area being laminated to the first substrate area and the second bonding area being laminated to the second substrate area; wherein a target parameter of the first bonding area is larger than a target parameter of the second bonding area, the target parameter including at least one of a viscosity and an elastic modulus.Type: GrantFiled: January 13, 2021Date of Patent: December 17, 2024Assignees: Beijing BOE Technology Development Co., Ltd., Chengdu BOE Optoelectronics Technology Co., Ltd.Inventors: Chao Wang, Binfeng Feng, Xingguo Liu
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Publication number: 20240395176Abstract: Provided are a supporting backplane and a display apparatus. The supporting backplane is arranged at one side of a flexible display panel, and the supporting backplane at least comprises a main bending area, wherein a bending axis corresponding to the main bending area extends in a first direction; the main bending area is provided with a plurality of first hollow holes, the plurality of first hollow holes being arranged in an array in the first direction and a second direction, which is orthogonal to the first direction; each of the first hollow holes is provided with a first middle hole area, and first arc-shaped hole areas located at two sides of the first middle hole area in the first direction.Type: ApplicationFiled: August 1, 2024Publication date: November 28, 2024Applicants: CHENGDU BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.Inventors: Zuquan CHEN, Wei QING, Xingguo LIU, Shaokui LIU, Zhihui WANG, Wei ZENG, Danping SHEN, Qiang TANG, Ce WANG
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Publication number: 20240360146Abstract: Disclosed are a Bruton's tyrosine kinase and a mutant degrader thereof; or a stereoisomer thereof, or a stereoisomer mixture thereof or a pharmaceutically acceptable salt thereof, and an application thereof in the preparation of a drug for treating diseases, disorders or conditions that would benefit from the degradation of the Bruton's tyrosine kinase and the mutant thereof. The compound of the present invention can degrade BTK protein, can degrade BTKC481S protein, has an anti-proliferation inhibiting effect on tumor cell strains Mino and OCI-LY10, shows good anti-tumor activity in an OCI-LY10 subcutaneous transplantation tumor model, has an inhibiting effect on B cell activation, and can be applied to B cell or plasma cell proliferative diseases and autoimmune diseases. The compound of the present invention has good oral absorption properties, and can be applied to oral treatment of human or animal B cell or plasma cell proliferative diseases and autoimmune diseases.Type: ApplicationFiled: June 30, 2022Publication date: October 31, 2024Inventors: Xinglu ZHOU, Jia LI, Xingguo LIU, Yubo ZHOU, Miao HU, Xiaomin LUO, Jiangfeng XIE, Weijuan KAN, Mingbo SU, Yizhe WU
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Publication number: 20240325381Abstract: The present application relates to uses of flunarizine and a method for controlling the number of intercellular mitochondria. The uses include use of the flunarizine in removing intracellular mitochondria, and use of the flunarizine in the preparation of a medicament for preventing and/or treating a disease associated with mitochondrial abnormality. The method includes: controlling the total amount of mitochondria in the brain by taking the flunarizine; contacting the flunarizine with cells to be treated, and controlling the total amount of the intercellular mitochondria based on the influence of the contact time on the removal amount of the mitochondria.Type: ApplicationFiled: June 12, 2024Publication date: October 3, 2024Inventors: Xingguo LIU, Feixiang BAO
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Publication number: 20240317689Abstract: Disclosed in the present invention is a compound having a structure shown in general formula I, or a stereoisomer thereof, a pharmaceutically acceptable salt thereof, or a solvate thereof. Further disclosed in the present invention are a composition comprising the compound, a preparation and an application. The compound of the present invention has a significant activation effect on KCNQ2/3 potassium ions, and can be used for treating diseases related to potassium channel ion flow, especially for treating central nervous system diseases.Type: ApplicationFiled: August 26, 2022Publication date: September 26, 2024Inventors: Miao HU, Yizhe WU, Xingguo LIU, Xinglu ZHOU
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Patent number: 12080197Abstract: Provided are a supporting backplane and a display apparatus. The supporting backplane is arranged at one side of a flexible display panel, and the supporting backplane at least comprises a main bending area, wherein a bending axis corresponding to the main bending area extends in a first direction; the main bending area is provided with a plurality of first hollow holes, the plurality of first hollow holes being arranged in an array in the first direction and a second direction, which is orthogonal to the first direction; each of the first hollow holes is provided with a first middle hole area, and first arc-shaped hole areas located at two sides of the first middle hole area in the first direction.Type: GrantFiled: May 26, 2021Date of Patent: September 3, 2024Assignees: CHENDU BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.Inventors: Zuquan Chen, Wei Qing, Xingguo Liu, Shaokui Liu, Zhihui Wang, Wei Zeng, Danping Shen, Qiang Tang, Ce Wang
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Publication number: 20240200048Abstract: Provided are a polypeptide translated by a circular RNA Circ-ACE2 and an application thereof, the circular RNA molecule comprising at least one of the following sequences: 1) an RNA sequence as set forth in SEQ ID NO: 1; 2) an RNA sequence having at least 70% identity with 1), preferably an RNA sequence having at least 80% identity with 1), preferably an RNA sequences having at least 85% identity with 1), preferably an RNA sequence having at least 90% identity with 1), preferably an RNA sequence having at least 95% identity with 1), and more preferably, an RNA sequence having at least 99% identity with 1).Type: ApplicationFiled: December 1, 2023Publication date: June 20, 2024Inventors: Xingguo LIU, Ming LIU, Maolei ZHANG, Guangsuo XING, Shan LIANG
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Patent number: 11945202Abstract: A curved surface lamination device, comprising a profiling jig (01), the profiling jig (01) comprising a base (101) and a profiling portion (102), with the profiling portion (102) being configured to support a carrier film (02), and the side of the base (101) facing away from the profiling portion (102) being provided with an opening; and a lower jig (03), comprising a first sinking groove (301), with part of the base (101) being inserted into the first sinking groove (301), such that the lower jig (03) encloses a hollow structure (E) with the base (101) at the opening position.Type: GrantFiled: May 12, 2021Date of Patent: April 2, 2024Assignees: Chengdu BOE Optoelectronics Technology Co., Ltd., BOE Technology Group Co., Ltd.Inventors: Xingguo Liu, Wei Qing, Qiang Tang, Shaokui Liu, Wenwei Mo
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Patent number: 11938707Abstract: A laminating device includes: a plate being bendable, having a resilience characteristic and for bearing the flexible substrate; a supporting base platform for supporting the plate and driving the plate and the flexible substrate on the plate to move; a bending assembly for applying stress to drive the plate and the flexible substrate on the plate to be bent towards a side, facing away from the flexible substrate, of the plate, and for releasing stress to allow the plate and the flexible substrate to rebound; and a fixing fixture for fixing the protective cover plate. The protective cover plate is used to be laminated to the flexible substrate, a shape of the fixing fixture is same as or similar to that of the protective cover plate, the fixing fixture is bent to form an accommodating space, and the protective cover plate is fixed in the accommodating space.Type: GrantFiled: December 30, 2020Date of Patent: March 26, 2024Assignees: Chengdu BOE Optoelectronics Technology Co., Ltd., BOE Technology Group Co., Ltd.Inventors: Xingguo Liu, Qiang Tang, Zhihui Wang, Wei Qing, Ce Wang, Shaokui Liu, Jia Deng, Jialin Wang, Zuquan Chen, Yuanyuan Chai
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Patent number: 11917859Abstract: Provided is a display module. The display module includes: a display panel and a heat dissipation structure; wherein the display panel includes a substrate and a display substrate layer disposed on the substrate, and the heat dissipation structure is disposed on a side, distal from the display substrate layer, of the substrate; and a gap is formed between at least a partial region of the heat dissipation structure and the substrate.Type: GrantFiled: June 1, 2021Date of Patent: February 27, 2024Assignees: Chengdu BOE Optoe ctroni Technology Co., Ltd., BOE Technology Group Co., Ltd.Inventors: Zuquan Chen, Wei Qing, Zhihui Wang, Xingguo Liu, Shaokui Liu, Wei Zeng, Danping Shen, Ce Wang, Qiang Tang
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Publication number: 20240057446Abstract: Provided are a foldable display and a terminal device. The foldable display includes a rigid substrate (30), a bonding layer (40), and a flexible display panel (50) which are sequentially stacked; wherein the rigid substrate (30) includes a first substrate area (31) and a second substrate area (32), the second substrate area (32) being foldable; and the bonding layer (40) includes a first bonding area (41) and a second bonding area (42), the first bonding area (41) being laminated to the first substrate area (31) and the second bonding area (42) being laminated to the second substrate area (32); wherein a target parameter of the first bonding area (41) is larger than a target parameter of the second bonding area (42), the target parameter including at least one of a viscosity and an elastic modulus.Type: ApplicationFiled: January 13, 2021Publication date: February 15, 2024Inventors: Chao WANG, Binfeng FENG, Xingguo LIU
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Patent number: 11897240Abstract: A laminating device and a laminating method are disclosed. The laminating device is used for laminating a flexible panel together with a curved cover plate. The curved cover plate is provided with a central area and an edge bending area located in a first direction in the central area. The laminating device comprises a movable mechanism, which is arranged opposite the curved cover plate in a second direction and comprises: a first movable base table and a second movable base table, which are arranged opposite each other in the first direction; and an elastic supporting member, which is provided with an elastic supporting portion, the elastic supporting portion covering parts of the first movable base table station and the second movable base table station that are close to the curved cover plate, and being used for fixing the flexible panel.Type: GrantFiled: April 9, 2021Date of Patent: February 13, 2024Assignees: Chengdu BOE Optoelectronics Technology Co., Ltd., BOE TECHNOLOGY GROUP CO., LTD.Inventors: Shaokui Liu, Wei Qing, Wenwei Mo, Qiang Tang, Xingguo Liu, Huiqiang Song, Ren Xiong
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Patent number: 11897239Abstract: A lamination device includes: an elastic lamination seat, including a deformation bearing portion, the deformation bearing portion including a bearing surface for bearing a to-be-laminated flexible display panel, and the bearing surface being configured as a curved surface protruding towards the cover plate; an auxiliary bearing film, configured to pre-bend and fix the to-be-laminated flexible display panel onto the bearing surface when the elastic lamination seat is in a natural state; and a driving mechanism, connected to the elastic lamination seat and configured to drive the elastic lamination seat to move towards or away from the cover plate, wherein when the driving mechanism drives the elastic lamination seat to move towards the cover plate, the elastic lamination seat is squeezed to produce elastic deformation and the bearing surface gradually laminates the flexible display panel onto the cover plate from the middle to two sides.Type: GrantFiled: January 7, 2021Date of Patent: February 13, 2024Assignees: Chengdu BOE Optoelectronics Technology Co., Ltd., BOE Technology Group Co., Ltd.Inventors: Xingguo Liu, Wei Qing, Shaokui Liu, Zhihui Wang, Zuquan Chen, Wei Zeng, Danping Shen, Jia Deng, Jialin Wang
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Publication number: 20240043430Abstract: The present disclosure discloses a crystal form of a casein kinase 1? inhibitor and a preparation method and use of the crystal form. Specifically, the present disclosure relates to a crystal form of the compound (S)-2-(1-(4-amino-3-(2,3-difluoro-4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-5-chloro-3-phenylquinazoline-4(3H)one methanesulfonate and a preparation method and use of the crystal form. The crystal form of the casein kinase 1? inhibitor compound of the present disclosure has good water solubility and oral absorption, and can be better used for the treatment of malignant tumors and autoimmune diseases that benefit from the inhibition of casein kinase 1? activity.Type: ApplicationFiled: December 21, 2021Publication date: February 8, 2024Inventors: Xinglu ZHOU, Xingguo LIU, Miao HU, Jianrong ZHU, Yizhe WU
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Publication number: 20240016006Abstract: Provided is a display panel including a plurality of sub-pixels and includes a substrate and a pixel defining layer, a light emitting device and a color film layer disposed on the substrate. The pixel defining includes M layers and M being a positive integer equal to or greater than 2, an m-th layer of pixel defining layer is covered on a surface of an (m?1)-th layer of pixel defining layer, and a refractive index nm-1 of the (m?1)-th layer of pixel defining layer is greater than a refractive index nm of the m-th layer of pixel defining layer, and wherein 2?m?M.Type: ApplicationFiled: May 7, 2021Publication date: January 11, 2024Inventors: Zuquan CHEN, Wei QING, Xingguo LIU, Shaokui LIU, Zhihui WANG, Wei ZENG, Danping SHEN, Qiang TANG, Ce WANG
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Patent number: 11826998Abstract: The present disclosure relates to the technical field of display product preparation, and in particular discloses a flexible display panel lamination device which is used for laminating a to-be-laminated flexible display panel onto a cover plate, and includes a base and an elastic lamination part arranged on the base. The elastic lamination part is provided with a first surface for bearing the to-be-laminated flexible display panel and a second surface opposite to the first surface; the second surface is symmetrically provided with two supporting protruding ribs; the two supporting protruding ribs are respectively fixed in two fixation grooves formed on the base; a gap is formed between a portion, located between the two supporting protruding ribs, of the second surface of the elastic lamination part and the base; and a portion, close to the edge, of the second surface of the elastic lamination part is supported on the base.Type: GrantFiled: January 6, 2021Date of Patent: November 28, 2023Assignees: Chengdu BOE Optoelectronics Technology Co., Ltd., BOE Technology Group Co., Ltd.Inventors: Shaokui Liu, Wei Qing, Zhihui Wang, Xingguo Liu, Zuquan Chen, Wei Zeng, Danping Shen, Yue Wei, Ce Wang, Qiang Tang
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Publication number: 20230356518Abstract: A laminating device includes: a plate being bendable, having a resilience characteristic and for bearing the flexible substrate; a supporting base platform for supporting the plate and driving the plate and the flexible substrate on the plate to move; a bending assembly for applying stress to drive the plate and the flexible substrate on the plate to be bent towards a side, facing away from the flexible substrate, of the plate, and for releasing stress to allow the plate and the flexible substrate to rebound; and a fixing fixture for fixing the protective cover plate. The protective cover plate is used to be laminated to the flexible substrate, a shape of the fixing fixture is same as or similar to that of the protective cover plate, the fixing fixture is bent to form an accommodating space, and the protective cover plate is fixed in the accommodating space.Type: ApplicationFiled: December 30, 2020Publication date: November 9, 2023Inventors: Xingguo LIU, Qiang TANG, Zhihui WANG, Wei QING, Ce WANG, Shaokui LIU, Jia DENG, Jialin WANG, Zuquan CHEN, Yuanyuan CHAI