Patents by Inventor Xingxun Zhu

Xingxun Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SMAC mimetics used as IAP inhibitors and use thereof
    Patent number: 11358950
    Abstract: Disclosed are a class of SMAC mimetics used as IAP inhibitors, and in particular disclosed are compounds as shown in formula (I), isomers thereof, and pharmaceutically acceptable salts thereof. The IAP inhibitors are drugs for treating cancers, in particular breast cancer.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: June 14, 2022
    Assignee: CHIA TAI TIANGQING PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Yingchun Liu, Zhaobing Xu, Lihong Hu, Charles Z. Ding, Xingxun Zhu, Guoping Hu, Jian Li, Shuhui Chen
  • CRYSTALLIZATION OF SMAC MIMIC USED AS IAP INHIBITOR AND PREPARATION METHOD THEREOF
    Publication number: 20220177453
    Abstract: Provided are a crystallization of an SMAC mimic used as an IAP inhibitor and a preparation method thereof; also comprised is the use of said crystallization in the preparation of a drug for treating cancer benefiting from cIAP1 inhibition. The compound of formula (I) has high crystallization stability and low hygroscopicity, and has advantages in terms of physical properties, safety, and metabolic stability, and has high drug value.
    Type: Application
    Filed: May 9, 2020
    Publication date: June 9, 2022
    Inventors: Yingchun Liu, Zhaobing Xu, Lihong Hu, Charles Z. Ding, Xingxun Zhu, Shuhui Chen
  • SMAC MIMETICS USED AS IAP INHIBITORS AND USE THEREOF
    Publication number: 20210371400
    Abstract: Disclosed are a class of SMAC mimetics used as IAP inhibitors, and in particular disclosed are compounds as shown in formula (I), isomers thereof, and pharmaceutically acceptable salts thereof. The IAP inhibitors are drugs for treating cancers, in particular breast cancer.
    Type: Application
    Filed: November 13, 2018
    Publication date: December 2, 2021
    Inventors: Yingchun Liu, Zhaobing Xu, Lihong Hu, Charles Z. Ding, Xingxun Zhu, Guoping Hu, Jian Li, Shuhui Chen