Patents by Inventor Xingzhou Li

Xingzhou Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110065795
    Abstract: The present invention relates to (1S,2S,3S,4R)-3-[(1S)-1-acetylamino-2-ethyl-butyl]-4-guanidino-2-hydroxy-cyclopentyl-1-carboxylic acid hydrates compounds, preparing methods thereof, pharmaceutical compositions containing said compounds and preparing methods thereof, and the clinical uses of said compounds as neuramidinase inhibitors for anti-influenza.
    Type: Application
    Filed: August 13, 2008
    Publication date: March 17, 2011
    Inventors: Song Li, Wu Zhong, Zhibing Zheng, Xinbo Zhou, Junhai Xiao, Yunde Xie, Lili Wang, Xingzhou Li, Guoming Zhao, Xiaokui Wang, Hongying Liu
  • Publication number: 20110009427
    Abstract: The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt or solvate thereof. Various substituents in the formula (I) are as defined in the specification. The present invention also relates to a pharmaceutical composition comprising the compound of formula (I), the preparation method of compound of formula (I), and the use of the compound for the preparation of a medicament for treating and/or preventing human peroxisome proliferators activated receptor ? (hPPAR?)-associated diseases and risk factors.
    Type: Application
    Filed: July 18, 2008
    Publication date: January 13, 2011
    Applicant: INSTITUE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA
    Inventors: Song Li, Yanbo Yang, Junhai Xiao, Wu Zhong, Zhibing Zheng, Xingzhou Li, Yunde Xie, Lili Wang, Hongying Liu
  • Publication number: 20100179116
    Abstract: The present invention relates to arene connected polyamine macrocyclic derivatives represented by general formula I, pharmaceutically acceptable salts or hydrates thereof which have anti-HIV activities, in which the definitions of substituents are as defined in the description; to preparation methods of the compounds of formula I; to pharmaceutical compositions containing the compounds of formula I or their pharmaceutically acceptable salts or hydrates; to the use of the compounds of formula I or their pharmaceutically acceptable salts or hydrates for the preparation of a medicament for the treatment and prevention of HIV-associated diseases.
    Type: Application
    Filed: May 30, 2008
    Publication date: July 15, 2010
    Inventors: Song Li, Jing Su, Yao Liu, Junhai Xiao, Lili Wang, Wu Zhong, Zhibing Zheng, Yunde Kie, Xingzhou Li, Guoming Zhao, Xiaokui Wang, Xinbo Zhou, Hongying Liu
  • Publication number: 20100087448
    Abstract: The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt or hydrate thereof, to a process for preparing the compound of formula (I), and to use of the compound of formula (I) or a pharmaceutically acceptable salt or hydrate thereof as a medicament, in particular as a medicament for the treatment and prevention of type B hepatitis.
    Type: Application
    Filed: July 9, 2007
    Publication date: April 8, 2010
    Inventors: Song Li, Guoming Zhao, Guangqiang Xia, Lili Wang, Zhibing Zheng, Yunde Xie, Wu Zhong, Junhai Xiao, Xingzhou Li, Hao Cui
  • Publication number: 20100004268
    Abstract: The present invention relates to an optically pure compound of formula (I) or a pharmaceutically acceptable salt or hydrate thereof, a process for preparing the optically pure compound of formula (I), and use of the optically pure compound of formula (I) or a pharmaceutically acceptable salt or hydrate thereof as a medicament, in particular as a medicament for the treatment and prevention of type B hepatitis.
    Type: Application
    Filed: July 9, 2007
    Publication date: January 7, 2010
    Inventors: Song Li, Guangqiang Xia, Guoming Zhao, Lili Wang, Zhibing Zheng, Yunde Xie, Wu Zhong, Junhai Xiao, Xingzhou Li, Hao Cui
  • Publication number: 20090176877
    Abstract: The present invention relates to an oseltamivir phosphate granule and preparation method thereof. The said granule comprises 1.97-19.8 wt. % oseltamivir phosphate, 75.0-97.5 wt. % diluent, 0.1-5.0 wt. % binder, optionally 1.0-5.0 wt. % edible flavouring essence, sweetener and/or edible pigment. It is prepared by using 30-55 v/v % aqueous ethanol solution as moistening agent. The granules prepared by the formulation and method according to the present invention have good uniformity and stability and are water-soluble. The administration dosage of the granules can be conveniently selected based on the age and body weight of patients. The oseltamivir phosphate granule is suitable for administering to old people, children and flu gravis patients and those patients that swallow inconveniently or difficulty. The preparation of the granule is simple and low in production cost.
    Type: Application
    Filed: August 11, 2006
    Publication date: July 9, 2009
    Inventors: Song Li, Wu Zhong, Junhai Xiao, Yunde Xie, Xingzhou Li, Hao Cui, Zhibing Zheng