Abstract: The invention discloses a standardized method of quantum state verification based on optimal strategy. The specific steps are as follows: (1) Adjust the quantum device to generate the quantum states required; (2) Calculate the measurement basis under the optimal verification strategy; (3) The quantum device generates the quantum state copy by copy, and the optimal measurement basis is performed for each copy. The measurement results are recorded as 1 for success and 0 for failure; (4) Make statistics on the index of first failure Nfirst and the number of success events mpass in N measurements; (5) Estimate the confidence and fidelity of the target state generated by the equipment according to the statistical results, and evaluate and analyze the reliability of the equipment. The invention realizes the standardized verification of the reliability of the quantum device, and estimates the quantum state with fewer resources.

Abstract: A method of determining the cellular or genetic target of an antimicrobial compound includes cloning of a bacterial gene into an expression vector with an inducible promoter and determining whether increasing expression of the cloned gene in the cell will result in resistance to an antimicrobial compound. Also, the method can include incorporation of every gene of a bacterial strain into expression vectors having an inducible promoter, induction, treating with an antimicrobial compound, isolating the gene clone that confers cells resistant to the compound, and determining the identity of the resistant gene by various methods including DNA microarrays and gene sequencing.

Abstract: The invention provides methods of modulating the activity of MurA polypeptides, particularly to treat disease.

Abstract: A method of determining the cellular or genetic target of an antimicrobial compound includes cloning of a bacterial gene into an expression vector with an inducible promoter and determining whether increasing expression of the cloned gene in the cell will result in resistance to an antimicrobial compound. Also, the method can include incorporation of every gene of a bacterial strain into expression vectors having an inducible promoter, induction, treating with an antimicrobial compound, isolating the gene clone that confers cells resistant to the compound, and determining the identity of the resistant gene by various methods including DNA microarrays and gene sequencing.

Abstract: The invention provides ups (undecaprenyl diphosphate synthase) polypeptides and polynucleotides encoding ups (undecaprenyl diphosphate synthase) polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ups (undecaprenyl diphosphate synthase) polypeptides to screen for antibacterial compounds.

Abstract: The invention provides ups (ugc) polypeptides and polynucleotides encoding ups (ugc) polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ups (ugc) polypeptides to screen for antibacterial compounds.

Abstract: The invention provides ups polypeptides and polynucleotides encoding ups polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ups polypeptides to screen for antibacterial compounds.

Abstract: A method of determining the cellular or genetic target of an antimicrobial compound includes cloning of a bacterial gene into an expression vector with an inducible promoter and determining whether increasing expression of the cloned gene in the cell will result in resistance to an antimicrobial compound. Also, the method can include incorporation of every gene of a bacterial strain into expression vectors having an inducible promoter, induction, treating with an antimicrobial compound, isolating the gene clone that confers cells resistant to the compound, and determining the identity of the resistant gene by various methods including DNA microarrays and gene sequencing.

Abstract: The invention provides tktA polypeptides and polynucleotides encoding tktA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ttA polypeptides to screen for antibacterial compounds.

Abstract: The invention provides MurA polypeptides and polynucleotides encoding MurA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing MurA polypeptides to screen for antibacterial compounds.

Abstract: The invention provides ups polypedes and polynucleotides encoding ups polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ups polypeptides to screen for antibacterial compounds.

Abstract: The invention provides ups (ugc) polypeptides and polynucleotides encoding ups (ugc) polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ups (ugc) polypeptides to screen for antibacterial compounds.

Abstract: The invention provides tktA polypeptides and polynucleotides encoding tktA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tktA polypeptides to screen for antibacterial compounds.