Abstract: Disclosed herein include novel blood-brain barrier (BBB)-crossing receptors on the BBB interface, targeting peptides and derivatives thereof capable of binding to the novel receptors, and related methods of using the receptors to increase the permeability of the BBB and to deliver an agent to a nervous system (e.g., CNS). In some embodiments, the BBB-crossing receptor is LRP6. Disclosed herein also include recombinant adeno-associated viruses (rAAVs) with increased specificity and transduction efficiency across the BBB and related compositions and methods of treating various diseases and conditions.

Abstract: The present disclosure is directed to a two-component bonding agent composition and a process for applying a layer of the bonding agent composition to substrate layers to make laminates.

Abstract: An adhesive composition is provided. The adhesive composition comprises the following components: (a) a polyacid polymer aqueous dispersion, wherein the polyacid polymer contains 50%˜100% by weight of one or more ethylenically unsaturated mono- or dicarboxylic acid/anhydrides; (b) a hydroxyl group-containing acrylic copolymer emulsion, wherein the hydroxyl group-containing acrylic copolymer is obtained from polymerizing a monomer mixture which contains 0.1-10% hydroxyl group-containing monomer, 0.1% to 20% weight unsaturated carboxylic acid and 30%-90% acrylic monomer, wherein the solid weight ratio of the above components (a) and (b) is 0.1:100 to 10:100, based on the solids of the components (a) and (b).

Abstract: Disclosed in the present application are a display substrate, a preparation method therefor, and a display device. The display substrate includes a rigid substrate, and a flexible film layer and a display function layer that are sequentially stacked on the rigid substrate. The rigid substrate is provided with an opening at a bending region to expose the flexible film layer in the bending region. The display substrate further includes a first light absorption portion in a display region and is on the side of the display region close to the bending region. The first light absorption portion is on the side of the rigid substrate facing away from the flexible film layer or is between the rigid substrate and the flexible film layer.

Abstract: A brightness compensation method and device of a display panel, a readable storage medium, and a display device are provided. A display panel is divided into at least one region. The region includes a to-be-corrected region. Wherein, the brightness compensation method includes: using a photographing component to photograph the display panel displaying a preset grayscale image; obtaining an image of the to-be-corrected region under a preset grayscale; obtaining brightness data of the to-be-corrected region, wherein the regional viewing angle is an included angle between a connection line of an optical center of a lens of the photographing component connecting to a center of the at least one region, and a normal of the display panel; correcting brightness of the to-be-corrected region to obtain corrected brightness data of the to-be-corrected region; and performing brightness compensation on the display panel according to the corrected brightness data of the to-be-corrected region.

Abstract: A display panel driving method, a display device and a driving device are provided. The method obtains a standard driving voltage value of a target pixel when a subject display content is being displayed and a target compression unit corresponding to the target pixel, determines a target compensation curve parameter from compressed de-Mura data corresponding to the target compression unit according to the standard driving voltage value, determines an effective driving voltage value of the target pixel when the subject content is being displayed according to a position information where the target pixel is in the target compression unit and the target compensation curve parameter, and drives the display panel according to the effective driving voltage. This method could correctly identify the corresponding decompression data and thus the decompressed data could be close to the actual data. This raises the decompression accuracy of decompressing the de-Mura data.

Abstract: A brightness compensation method and device of a display panel, a readable storage medium, and a display device are provided. A display panel is divided into at least one region. The region includes a to-be-corrected region. Wherein, the brightness compensation method includes: using a photographing component to photograph the display panel displaying a preset grayscale image; obtaining an image of the to-be-corrected region under a preset grayscale; obtaining brightness data of the to-be-corrected region, wherein the regional viewing angle is an included angle between a connection line of an optical center of a lens of the photographing component connecting to a center of the at least one region, and a normal of the display panel; correcting brightness of the to-be-corrected region to obtain corrected brightness data of the to-be-corrected region; and performing brightness compensation on the display panel according to the corrected brightness data of the to-be-corrected region.

Abstract: Disclosed in the present application are a method and a device for establishing a brightness correction database of a display panel, and a method and a device for correcting brightness of a display panel. The method for establishing the brightness correction database of the display panel includes: acquiring brightness defect data of pixel units having brightness defects in a detected image of the display panel, and classifying the brightness defects of the pixel units based on the brightness defect data; fitting a plurality of brightness-grayscale curves according to brightness of the pixel units corresponding to different types of the brightness defects at different grayscales respectively; and obtaining brightness correction data of the pixel units corresponding to different types of the brightness defects respectively based on the plurality of brightness-grayscale curves to form the brightness correction database, which can improve speed and accuracy of brightness defect correction of the display panel.

Abstract: A brightness correcting method of a display panel and a brightness correcting device are disclosed. The method divides a displayed image of the display panel into a first area and a plurality of second areas disposed surrounding the first area. A brightness correction factor of each of the second areas is obtained according to a brightness of the first area and a brightness of each of the second areas. An optical compensation value is adjusted according to the brightness correction factor. The method corrects a brightness of the display panel to allow uniformity of overall brightness of the display panel to meet requirements.

Abstract: A display panel driving method, a display device and a driving device are provided. The method obtains a standard driving voltage value of a target pixel when a subject display content is being displayed and a target compression unit corresponding to the target pixel, determines a target compensation curve parameter from compressed de-Mura data corresponding to the target compression unit according to the standard driving voltage value, determines an effective driving voltage value of the target pixel when the subject content is being displayed according to a position information where the target pixel is in the target compression unit and the target compensation curve parameter, and drives the display panel according to the effective driving voltage. This method could correctly identify the corresponding decompression data and thus the decompressed data could be close to the actual data. This raises the decompression accuracy of decompressing the de-Mura data.

Abstract: A flicker control circuit of liquid crystal devices (LCDs) includes a main control chip, a low differential voltage regulator (LDO) circuit, a first resistor, a second resistor, and a reset resistor. The main control chip includes an operational voltage input end, a common voltage output end, and a dividing reference voltage input end. The LDO circuit receives a voltage provided by an external power module and generates a dividing reference voltage in accordance with the received voltage. One end of the first resistor connects to the LDO circuit to receive the dividing reference voltage, and the other end of the first resistor connects to the dividing reference voltage input end. The flicker of the LCDs may be reduced such that the display performance of the LCDs may be enhanced.

Abstract: The present disclosure provides a gamma correction system and method. In the present disclosure, a gamma correction method used for a display panel of a liquid crystal display includes: measuring actual brightness values of preset highest grayscale and lowest grayscale of a central region of the display panel; calculating target brightness values of respective preset tie-point grayscales of the central area based on the actual brightness values, wherein the respective preset tie-point grayscale are located between the preset highest grayscale and the lowest grayscale; adjusting the respective preset tie-point grayscale of the central region and regions of both sides respectively according to the target brightness values, and computing compensating grayscale values of the adjusted respective preset tie-point grayscale; storing the compensating grayscale values, and correcting the gamma curves of the central region and the regions of both sides by using the stored compensating grayscale values.

Abstract: The present disclosure provides a gamma correction system and method. In the present disclosure, a gamma correction method used for a display panel of a liquid crystal display includes: measuring actual brightness values of preset highest grayscale and lowest grayscale of a central region of the display panel; calculating target brightness values of respective preset tie-point grayscales of the central area based on the actual brightness values, wherein the respective preset tie-point grayscale are located between the preset highest grayscale and the lowest grayscale; adjusting the respective preset tie-point grayscale of the central region and regions of both sides respectively according to the target brightness values, and computing compensating grayscale values of the adjusted respective preset tie-point grayscale; storing the compensating grayscale values, and correcting the gamma curves of the central region and the regions of both sides by using the stored compensating grayscale values.

Abstract: A flicker control circuit of liquid crystal devices (LCDs) includes a main control chip, a low differential voltage regulator (LDO) circuit, a first resistor, a second resistor, and a reset resistor. The main control chip includes an operational voltage input end, a common voltage output end, and a dividing reference voltage input end. The LDO circuit receives a voltage provided by an external power module and generates a dividing reference voltage in accordance with the received voltage. One end of the first resistor connects to the LDO circuit to receive the dividing reference voltage, and the other end of the first resistor connects to the dividing reference voltage input end. The flicker of the LCDs may be reduced such that the display performance of the LCDs may be enhanced.

Abstract: A driving method of a display panel including: providing a display panel including multiple data lines and pixel unit groups arranged in an array, each pixel unit group being divided into a first sub-pixel unit group and a second sub-pixel unit group alternately arranged along column direction, the first and the second sub-pixel unit groups each including multiple sub-pixels; in a same frame of image, the data lines scanning the first sub-pixel unit groups of the pixel unit groups; and driving signals on the data lines being performed with one time level switching and then the data lines scanning the second sub-pixel unit groups of the pixel unit groups. In the driving method of the invention, the level switching times of the driving signal on each data line is significantly decreased, the power consumption for driving the display panel can be reduced and display performance can be enhanced.

Abstract: The circuit of the present invention comprises a detection module and a feedback module, wherein an output end of a power supply management module is coupled to one end of a voltage level shift module, and the other end of the voltage level shift module is coupled to a first end of the detection module, and a second end of the detection module is coupled to a WOA route module or a GOA route module, and a third end of the detection is coupled to one end of the feedback module, and the other end of the feedback module is coupled to an enable end of the power supply management module, and the detection module detects whether the WOA route module or the GOA route module is short, and feeds back a short signal; the feedback module receives the short signal, and sends a disable signal to the enable end.

Abstract: The circuit of the present invention comprises a detection module and a feedback module, wherein an output end of a power supply management module is coupled to one end of a voltage level shift module, and the other end of the voltage level shift module is coupled to a first end of the detection module, and a second end of the detection module is coupled to a WOA route module or a GOA route module, and a third end of the detection is coupled to one end of the feedback module, and the other end of the feedback module is coupled to an enable end of the power supply management module, and the detection module detects whether the WOA route module or the GOA route module is short, and feeds back a short signal; the feedback module receives the short signal, and sends a disable signal to the enable end.

Abstract: The present invention discloses a backlight unit, including a backlight module including a light source for emitting light; a voltage generating unit for providing a driving voltage to the backlight unit; a backlight controlling unit for receiving a frame frequency signal and producing a cycle controlling signal having a same cycle time to the frame frequency signal; a backlight driving chip for producing a PWM signal according to the cycle controlling signal and a preset duty ratio D, wherein the PWM signal has a same cycle time to the cycle controlling time, and the duty ratio of the PWM signal is D in each cycle, the PWM signal being configured for controlling the voltage generating unit to provide or cut off the driving voltage to the backlight unit. The present invention also provides a method for driving the above backlight unit and a liquid crystal display including the backlight unit.

Abstract: The present invention discloses a liquid crystal display, including: a liquid crystal panel, which defines n first division zones in a first direction; a gate driver, which includes n gate driver chips respectively corresponding to the n first division zones, the gate driver chips each including a control unit and a first electrical resistance unit; a timing controller, which is arranged to supply a control signal to the liquid crystal display; and a common voltage generator, which supplies a common voltage source that is fed in sequence to the n gate driver chips.

Abstract: An LED backlight source used in a LCD device is disclosed. It comprises a boost circuit, boosting the input voltage to the operating voltage of an LED string; a current control module, connecting to a negative end of the LED string for modulating the operating voltage of the LED string; a microcontroller, providing the current control module with the second square wave signal to control the current control module for achieving current modulation; a boost driver chip, providing the boost circuit with a first square wave signal to the boost circuit for achieving voltage boost function; the boost driver chip receives a feedback regulation voltage found by the microcontroller and changes a duty ratio of the first square wave signal provided by the boost circuit according to the feedback regulation voltage, for modulating the operating voltage of the LED string.