Patents by Inventor Xinhua QIAO

Xinhua QIAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11529385
    Abstract: A composition is provided for promoting skeletal muscle oxidative muscle fiber generation. The composition comprises a Lycium barbarum water extract. The Lycium barbarum extract comprises polysaccharide, Lycium barbarum flavone, carotenoid, polyphenol, and Lycium barbarum pigment. The composition may further comprise one or more pharmaceutically acceptable excipients selected from such as a solvent, a co-solvent, an emulsifier, a preservative, a buffer, a protein powder, or a combination thereof. The composition may be used as medicine, functional product, or food supplement.
    Type: Grant
    Filed: August 25, 2021
    Date of Patent: December 20, 2022
    Assignee: Institute of Biophysics, Chinese Academy of Sciences
    Inventors: Chang Chen, Jiao Meng, Zhenyu Lv, Chuanxin Sun, Xinhua Qiao
  • Publication number: 20220072079
    Abstract: A composition is provided for promoting skeletal muscle oxidative muscle fiber generation. The composition comprises a Lycium barbarum water extract. The Lycium barbarum extract comprises polysaccharide, Lycium barbarum flavone, carotenoid, polyphenol, and Lycium barbarum pigment. The composition may further comprise one or more pharmaceutically acceptable excipients selected from such as a solvent, a co-solvent, an emulsifier, a preservative, a buffer, a protein powder, or a combination thereof. The composition may be used as medicine, functional product, or food supplement.
    Type: Application
    Filed: August 25, 2021
    Publication date: March 10, 2022
    Applicant: Institute of Biophysics, Chinese Academy of Sciences
    Inventors: Chang Chen, Jiao Meng, Zhenyu Lv, Chuanxin Sun, Xinhua Qiao
  • Patent number: 11135260
    Abstract: A composition is provided for promoting skeletal muscle oxidative muscle fiber generation. The composition comprises a Lycium barbarum water extract. The Lycium barbarum extract comprises polysaccharide, Lycium barbarum flavone, carotenoid, polyphenol, and Lycium barbarum pigment. The composition may further comprise one or more pharmaceutically acceptable excipients selected from such as a solvent, a co-solvent, an emulsifier, a preservative, a buffer, a protein powder, or a combination thereof. The composition may be used as medicine, functional product, or food supplement.
    Type: Grant
    Filed: December 30, 2020
    Date of Patent: October 5, 2021
    Assignee: Institute of Biophysics, Chinese Academy of Sciences
    Inventors: Chang Chen, Jiao Meng, Zhenyu Lv, Chuanxin Sun, Xinhua Qiao
  • Patent number: 11058716
    Abstract: Provided are a method, target and application for NO accumulation to decrease invasiveness of Pseudomonas aeruginosa; achieving NO accumulation by means of external NO donors or disruption of internal NO metabolism in an environment where Pseudomonas aeruginosa is growing or being cultured, in order to decrease production by Pseudomonas aeruginosa of the invasion factor pyocyanin. Utilizing even micro-quantities of NO can significantly inhibit Pseudomonas aeruginosa PCN (PCN synthesis down 82% with 60 ?M SNP treatment); by inhibiting NO reductase, an enzyme related to NO metabolism, PCN synthesis can be significantly inhibited (the PAO1-?nor strain has 84% PCN reduction). Using NO donors or inhibiting enzymes involved in Pseudomonas aeruginosa NO metabolism as a means of combating bacterial infectious disease does not affect the body's normal microflora like traditional antibiotics.
    Type: Grant
    Filed: January 9, 2020
    Date of Patent: July 13, 2021
    Inventors: Yi Wan, Chang Chen, Lei Gao, Yuying Zhang, Xinhua Qiao, Yan Wang
  • Publication number: 20210205395
    Abstract: A composition is provided for promoting skeletal muscle oxidative muscle fiber generation. The composition comprises a Lycium barbarum water extract. The Lycium barbarum extract comprises polysaccharide, Lycium barbarum flavone, carotenoid, polyphenol, and Lycium barbarum pigment. The composition may further comprise one or more pharmaceutically acceptable excipients selected from such as a solvent, a co-solvent, an emulsifier, a preservative, a buffer, a protein powder, or a combination thereof. The composition may be used as medicine, functional product, or food supplement.
    Type: Application
    Filed: December 30, 2020
    Publication date: July 8, 2021
    Applicant: Institute of Biophysics, Chinese Academy of Sciences
    Inventors: Chang Chen, Jiao Meng, Zhenyu Lv, Chuanxin Sun, Xinhua Qiao
  • Publication number: 20200147129
    Abstract: Provided are a method, target and application for NO accumulation to decrease invasiveness of Pseudomonas aeruginosa; achieving NO accumulation by means of external NO donors or disruption of internal NO metabolism in an environment where Pseudomonas aeruginosa is growing or being cultured, in order to decrease production by Pseudomonas aeruginosa of the invasion factor pyocyanin. Utilizing even micro-quantities of NO can significantly inhibit Pseudomonas aeruginosa PCN (PCN synthesis down 82% with 60 ?M SNP treatment); by inhibiting NO reductase, an enzyme related to NO metabolism, PCN synthesis can be significantly inhibited (the PAO1-?nor strain has 84% PCN reduction). Using NO donors or inhibiting enzymes involved in Pseudomonas aeruginosa NO metabolism as a means of combating bacterial infectious disease does not affect the body's normal microflora like traditional antibiotics.
    Type: Application
    Filed: January 9, 2020
    Publication date: May 14, 2020
    Inventors: Yi WAN, Chang CHEN, Lei GAO, Yuying ZHANG, Xinhua QIAO, Yan WANG
  • Patent number: 10537593
    Abstract: Provided are a method, target and application for NO accumulation to decrease invasiveness of Pseudomonas aeruginosa; achieving NO accumulation by means of external NO donors or disruption of internal NO metabolism in an environment where Pseudomonas aeruginosa is growing or being cultured, in order to decrease production by Pseudomonas aeruginosa of the invasion factor pyocyanin. Utilizing even micro-quantities of NO can significantly inhibit Pseudomonas aeruginosa PCN (PCN synthesis down 82% with 60 ?M SNP treatment); by inhibiting NO reductase, an enzyme related to NO metabolism, PCN synthesis can be significantly inhibited (the PAO1-?nor strain has 84% PCN reduction). Using NO donors or inhibiting enzymes involved in Pseudomonas aeruginosa NO metabolism as a means of combating bacterial infectious disease does not affect the body's normal microflora like traditional antibiotics.
    Type: Grant
    Filed: October 22, 2016
    Date of Patent: January 21, 2020
    Inventors: Yi Wan, Chang Chen, Lei Gao, Yuying Zhang, Xinhua Qiao, Yan Wang
  • Publication number: 20180311275
    Abstract: Provided are a method, target and application for NO accumulation to decrease invasiveness of Pseudomonas aeruginosa (P. aeruginosa); achieving NO accumulation by means of external NO donors or disruption of internal NO metabolism in an environment where P. aeruginosa is growing or being cultured, in order to decrease production by P. aeruginosa of the invasion factor pyocyanin. Utilizing even micro-quantities of NO can significantly inhibit P. aeruginosa PCN (PCN synthesis down 82% with 60 ?M SNP treatment); by inhibiting NO reductase, an enzyme related to NO metabolism, PCN synthesis can be significantly inhibited (the PAO1 ?nor strain has 84% PCN reduction). Using NO donors or inhibiting enzymes involved in P. aeruginosa NO metabolism as a means of combating bacterial infectious disease does not affect the body's normal microflora like traditional antibiotics.
    Type: Application
    Filed: October 22, 2016
    Publication date: November 1, 2018
    Inventors: Yi WAN, Chang CHEN, Lei GAO, Yuying ZHANG, Xinhua QIAO, Yan WANG