Abstract: This invention provides a system and method for setting image-monitoring regions for installing in an image-monitoring system to assist users in setting image-monitoring regions for the image-monitoring system to execute image-monitoring operations accordingly, the method including the steps of: dividing image data outputted by the image-monitoring system into a plurality of unit image regions; selecting unit image regions that need to be monitored according to the image data contained in each of the unit image regions; and having the image-monitoring system to execute a corresponding monitoring operation on the selected unit image regions, thereby making the setting operation of image-monitoring regions more direct and accurate for users' easy operation.