Abstract: A conjugate compounds or pharmaceutically acceptable salt thereof, comprises a payload and two or more kinds of cell-interacting molecules. The cell-interacting molecules are ligands capable of specifically binding to a cell surface receptor. A method of treating diseases, comprises delivering a payload to a subject.

Abstract: A monitoring system includes a reference station, a mobile station, a plurality of integrated sensing units, and a server. The reference station is configured to provide fixed reference coordinates to the server. The mobile station transmits multi-frequency electromagnetic wave signals to the integrated sensing units. Based on water depth and position information detected by sensors of the integrated sensing units in combination with information of electromagnetic wave signals as well as a propagation distance and time, displacement information of the integrated sensing units can be obtained. The data is transmitted to the mobile station, which further transmits the data to the server, to accomplish monitoring for the reservoir landslide water-level-fluctuation zone. Automated monitoring is achieved and the monitoring cycle covers the entire deformation and evolution phases of landslides.

Abstract: A conjugate compounds or pharmaceutically acceptable salt thereof, comprises a payload and two or more kinds of cell-interacting molecules. The cell-interacting molecules are ligands capable of specifically binding to a cell surface receptor. A method of treating diseases, comprises delivering a payload to a subject.

Abstract: A casing pipe extends in a vertical direction, and two adjacent casing pipes are connected by a plurality of link mechanisms; the link mechanism includes two supports, the two supports are hinged by a first pin to form a hinged portion, an upper end and a lower end of the link mechanism are hinged to two adjacent casing pipes by second pins separately, a sensor is fixed to the link mechanism, and the link mechanism has an initial state of extending in the vertical direction and an extending state in which the hinged portion extends outwards to be located on an outer side of the casing pipe; a driving mechanism drives a push portion to move towards the link mechanism; and a downward pressing apparatus is used for pressing a top end of the topmost casing pipe downwards to push the hinged portion into a side wall of the borehole.

Abstract: A casing pipe extends in a vertical direction, and two adjacent casing pipes are connected by a plurality of link mechanisms; the link mechanism includes two supports, the two supports are hinged by a first pin to form a hinged portion, an upper end and a lower end of the link mechanism are hinged to two adjacent casing pipes by second pins separately, a sensor is fixed to the link mechanism, and the link mechanism has an initial state of extending in the vertical direction and an extending state in which the hinged portion extends outwards to be located on an outer side of the casing pipe; a driving mechanism drives a push portion to move towards the link mechanism; and a downward pressing apparatus is used for pressing a top end of the topmost casing pipe downwards to push the hinged portion into a side wall of the borehole.

Abstract: A device for monitoring underwater surface overflow seepage of a landslide includes an underwater seepage monitor arranged on an underwater sliding mass, the underwater seepage monitor includes a bearing housing, a flow guide pipe, a silt discharging cover plate and a silt discharging mechanism, the silt discharging mechanism driving the silt discharging cover plate to be switched between a blocking position and an opening position. Considering complex environmental factors, a multifunctional flow monitor is embedded into a sliding mass and surrounds an outlet of the underwater landslide seepage. A silt discharging hole is provided in the bearing housing, the silt discharging mechanism is configured to drive the silt discharging cover plate to be located at the opening position, and silt in the bearing housing may be discharged from the silt discharging hole, such that the problem of silt deposition caused by overflow seepage of an underwater landslide is solved.

Abstract: The present disclosure discloses a conjugate compound or a pharmaceutically acceptable salt thereof, comprising a payload and two targeting molecules. Further disclosed herein is a pharmaceutical composition, comprising the conjugate compound or the pharmaceutically acceptable salt thereof. The present disclosure additionally relates to a method for delivering a payload to a subject in need thereof, and a method for treating a disease, wherein the methods comprise administering to the subject a therapeutically effective amount of the conjugate compound or the pharmaceutically acceptable salt thereof, or the pharmaceutical composition as disclosed herein.

Abstract: The present disclosure relates to a device for laying out a prefabricated magnetic field and a method for responding state of a slip mass in the prefabricated magnetic field. The device may include a traction mechanism, a control mechanism and a layout probe. The layout probe may include a shell, a circuit board and at least one set of layout mechanism equipped in the shell. The layout mechanism may include a cartridge, a screw pole, an electromagnet, a driving mechanism and a pressing mechanism. The traction mechanism may lay down the layout probe to a default location of a drill hole. The control mechanism may control the driving mechanism to transmit an uppermost permanent-magnet in the layout probe to the cartridge nozzle and be attracted by the electromagnet. The pressing mechanism may move the electromagnet which presses the permanent-magnet in the inner wall of the drill hole.

Abstract: The present disclosure relates to a device for laying out a prefabricated magnetic field and a method for responding state of a slip mass in the prefabricated magnetic field. The device may include a traction mechanism, a control mechanism and a layout probe. The layout probe may include a shell, a circuit board and at least one set of layout mechanism equipped in the shell. The layout mechanism may include a cartridge, a screw pole, an electromagnet, a driving mechanism and a pressing mechanism. The traction mechanism may lay down the layout probe to a default location of a drill hole. The control mechanism may control the driving mechanism to transmit an uppermost permanent-magnet in the layout probe to the cartridge nozzle and be attracted by the electromagnet. The pressing mechanism may move the electromagnet which presses the permanent-magnet in the inner wall of the drill hole.

Abstract: A liquid crystalline polyester resin composition is described, which includes a liquid crystalline polyester; and an amide compound including the following structural units (I) to (III), and having a melting point of ?100° C. and a volume average particle diameter of ?5 ?m and ?50 ?m, wherein a content of the amide compound is ?0.005 parts by mass and ?0.1 parts by mass with respect to 100 parts by mass of a content of the liquid crystalline polyester, structural unit (I): CH3—X—CO—, X represents an aliphatic hydrocarbon group having ?10 carbon atoms or a hydroxy hydrocarbon group in which one or more hydrogen atoms of an aliphatic hydrocarbon group are substituted with a hydroxy group; structural unit (II): —HN—Y—NH—, Y represents a hydrocarbon group having ?2 carbon atoms; structural unit (III): —OC—Z—CO—, Z represents an aliphatic hydrocarbon group having ?4 carbon atoms, an alicyclic hydrocarbon group, or an aromatic hydrocarbon group.

Abstract: A liquid crystal polyester composition containing a liquid crystal polyester, a fibrous filler having a number average fiber diameter of at least 15 ?m but not more than 25 ?m, and a plate-like filler is provided. The total amount of the fibrous filler and the plate-like filler is at least 65 parts by mass but not more than 105 parts by mass per 100 parts by mass of the liquid crystal polyester.

Abstract: A conjugate compounds or pharmaceutically acceptable salt thereof, comprises a payload and two or more kinds of cell-interacting molecules. The cell-interacting molecules are ligands capable of specifically binding to a cell surface receptor. A method of treating diseases, comprises delivering a payload to a subject.