Patents by Inventor Xin-Min Zhang

Xin-Min Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • C21 polypeptide that modulates the stability of transcriptional regulatory complexes regulating nuclear hormone receptor activity
    Patent number: 6982317
    Abstract: A gene in humans and mice, designated C21, encodes a family of proteins that play a role in transcriptional regulation. Two isoforms (? and ?) produced by alternative splicing has been identified in humans. A transgenic model was created that shows that over-expression of C21 in mouse hematopoietic cells alters myeloid development and suggests that members of this family are involved in regulating stem cell differentiation. Over-expressing C21 in 3T3 fibroblasts increases their resistance to apoptotic stimuli. The C21 protein forms a complex with a class of molecules that plays a critical role in transcription, the co-repressors of nuclear hormone receptors.
    Type: Grant
    Filed: November 15, 2001
    Date of Patent: January 3, 2006
    Assignee: New York University
    Inventors: Ross S. Basch, Xin-Min Zhang
  • PROTEIN THAT MODULATES THE STABILITY OF TRANSCRIPTIONAL REGULATORY COMPLEXES REGULATING NUCLEAR HORMONE RECEPTOR ACTIVITY, DNA ENCODING SAME, AND ANTIBODIES THERETO
    Publication number: 20050119456
    Abstract: A gene in humans and mice, designated C21, encodes a family of proteins that play a role in transcriptional regulation. Two isoforms (? and ?) produced by alternative splicing has been identified in humans. A transgenic model was created that shows that over-expression of C21 in mouse hematopoietic cells alters myeloid development and suggests that members of this family are involved in regulating stem cell differentiation. Over-expressing C21 in 3T3 fibroblasts increases their resistance to apoptotic stimuli. The C21 protein forms a complex with a class of molecules that plays a critical role in transcription, the co-repressors of nuclear hormone receptors.
    Type: Application
    Filed: November 15, 2001
    Publication date: June 2, 2005
    Applicant: New York University
    Inventors: Ross Basch, Xin-Min Zhang