Patents by Inventor Xinnian Dong

Xinnian Dong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230227838
    Abstract: The present disclosure describes compositions and methods for promoting cell survival against biotic and abiotic stress and during plant immune responses.
    Type: Application
    Filed: June 22, 2021
    Publication date: July 20, 2023
    Inventors: Xinnian DONG, Raul ZAVALIEV
  • Patent number: 10584346
    Abstract: The present invention relates to new methods to study and control the expression of plant genes, particularly nucleotide sequences located downstream from regions comprising binding sites for transcription factors, such as the cis-element translocon 1 (TL1) comprising GAAGAAGAA and similar sequences. The invention relates to isolated nucleotide sequences comprising a regulatory region comprising a promoter operably-linked to one or more upstream open reading frames (uORFs) and one or more downstream open reading frames (dORFs) encoding one or more functional polypeptides, including transcription factors such as TBF1, reporter polypeptides, and polypeptides conferring resistance to drugs, resistance of plants viral, bacterial, or fungal pathogens, and polypeptides involved in the growth of plants.
    Type: Grant
    Filed: June 8, 2018
    Date of Patent: March 10, 2020
    Assignee: Duke University
    Inventors: Karolina M. Pajerowska-Mukhtar, Guoyong Xu, Xinnian Dong
  • Publication number: 20190352664
    Abstract: The invention generally relates to compositions (including constructs, vectors, and cells) and methods of using such compositions for controlling gene expression. More specifically, the invention relates to use of R-motif sequences and/or uORF sequences to control gene expression.
    Type: Application
    Filed: February 2, 2018
    Publication date: November 21, 2019
    Inventors: XINNIAN DONG, GEORGE GREENE, GUOYONG XU
  • Publication number: 20180273965
    Abstract: The present invention relates to new methods to study and control the expression of plant genes, particularly nucleotide sequences located downstream from regions comprising binding sites for transcription factors, such as the cis-element translocon 1 (TL1) comprising GAAGAAGAA and similar sequences. The invention relates to isolated nucleotide sequences comprising a regulatory region comprising a promoter operably-linked to one or more upstream open reading frames (uORFs) and one or more downstream open reading frames (dORFs) encoding one or more functional polypeptides, including transcription factors such as TBF1, reporter polypeptides, and polypeptides conferring resistance to drugs, resistance of plants viral, bacterial, or fungal pathogens, and polypeptides involved in the growth of plants.
    Type: Application
    Filed: June 8, 2018
    Publication date: September 27, 2018
    Applicant: Duke University
    Inventors: Karolina M. Pajerowska-Mukhtar, Guoyong Xu, Xinnian Dong
  • Patent number: 10017773
    Abstract: The present invention relates to new methods to study and control the expression of plant genes, particularly nucleotide sequences located downstream from regions comprising binding sites for transcription factors, such as the cis-element translocon 1 (TL1) comprising GAAGAAGAA and similar sequences. The invention relates to isolated nucleotide sequences comprising a regulatory region comprising a promoter operably-linked to one or more upstream open reading frames (uORFs) and one or more downstream open reading frames (dORFs) encoding one or more functional polypeptides, including transcription factors such as TBF1, reporter polypeptides, and polypeptides conferring resistance to drugs, resistance of plants viral, bacterial, or fungal pathogens, and polypeptides involved in the growth of plants.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: July 10, 2018
    Assignee: Duke University
    Inventors: Karolina M. Pajerowska-Mukhtar, Guoyong Xu, Xinnian Dong
  • Publication number: 20150113685
    Abstract: The present invention relates to new methods to study and control the expression of plant genes, particularly nucleotide sequences located downstream from regions comprising binding sites for transcription factors, such as the cis-element translocon 1 (TL1) comprising GAAGAAGAA and similar sequences. The invention relates to isolated nucleotide sequences comprising a regulatory region comprising a promoter operably-linked to one or more upstream open reading frames (uORFs) and one or more downstream open reading frames (dORFs) encoding one or more functional polypeptides, including transcription factors such as TBF1, reporter polypeptides, and polypeptides conferring resistance to drugs, resistance of plants viral, bacterial, or fungal pathogens, and polypeptides involved in the growth of plants.
    Type: Application
    Filed: December 19, 2014
    Publication date: April 23, 2015
    Inventors: Karolina M. PAJEROWSKA-MUKHTAR, Guoyong XU, Xinnian DONG
  • Publication number: 20020138872
    Abstract: Genomic and cDNA sequences encoding plant acquired resistance proteins are disclosed.
    Type: Application
    Filed: August 8, 1997
    Publication date: September 26, 2002
    Inventors: XINNIAN DONG, FREDERICK M. AUSUBEL, HUI CAO, JANE GLAZEBROOK
  • Publication number: 20020073447
    Abstract: Genomic and cDNA sequences encoding plant acquired resistance proteins are disclosed. Expression of these polypeptides in transgenic plants are useful for providing enhanced defense mechanisms to combat plant diseases.
    Type: Application
    Filed: July 17, 2001
    Publication date: June 13, 2002
    Inventors: Xinnian Dong, Frederick M. Ausubel, Hui Cao, Jane Glazebrook
  • Patent number: 6137031
    Abstract: The present invention provides nucleic acids that encode bZIP polypeptides that are capable of interacting with NPR1. The present invention also provides for bZIP polypeptides that are capable of interacting with NPR1 as well as transgenic plants comprising a nucleic acids that encode bZIP polypeptides that are capable of interacting with NPR1. Also provided by the present invention is a method for enhancing resistance of plants to pathogens by introducing a recombinant expression cassette comprising a plant promoter operably linked to a polynucleotide sequence encoding a bZIP polypeptide that interacts with NPR1. The present invention also provides for a method of identifying additional bZIP polypeptides that interact with NPR1.
    Type: Grant
    Filed: March 11, 1999
    Date of Patent: October 24, 2000
    Assignees: Duke University, The Regents of the University of California
    Inventors: Yuelin Zhang, Mark Kinkema, Xinnian Dong, Pamela Ronald, Maw Shenq Chern