Patents by Inventor Xinrong Liu

Xinrong Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STABLE FORMULATION OF HUMAN PAPILLOMAVIRUS VIRUS-LIKE PARTICLE VACCINE
    Publication number: 20240075124
    Abstract: Provided is a stable formulation of a human papillomavirus virus-like particle vaccine. The stable formulation is composed of a human papillomavirus virus-like particle, a buffer solution, an osmotic pressure regulator, a surfactant and an aluminum adjuvant, wherein the components of the vaccine comprise HPV virus-like particles assembled by L1 proteins of HPV types 6, 11, 16, 18, 31, 33, 45, 52 and 58, and one or more HPV virus-like particles assembled by L1 proteins of other pathogenic HPV types. The formulation can enhance the stability of the vaccine and prolong the validity period of the vaccine in an aqueous formulation.
    Type: Application
    Filed: January 13, 2022
    Publication date: March 7, 2024
    Inventors: Yan LIU, Ping HU, Xinrong CHANG
  • Human cancer-related gene, its encoded products and applications
    Patent number: 9470690
    Abstract: The invention discloses a human cancer-related gene, LAPTM4B, its encoded products and their applications thereof. This human cancer-related gene provided by this invention comprises one of the following nucleotide sequences: (1) SEQ ID No: 1, SEQ ID No: 2, SEQ ID No: 3, SEQ ID No: 6, or SEQ ID No: 8 in the sequence listings; (2) Polynucleotides that encode the protein sequences of SEQ ID No: 4, SEQ ID No: 5, or SEQ ID No: 7 in the sequence listings; (3) DNA sequences having above 90% homology with the DNA sequences specified by SEQ ID No: 1, SEQ ID No: 2, SEQ ID No: 3, SEQ ID No: 6, or SEQ ID No: 8 in the sequence listings, and these DNA sequences encode the proteins with the same or similar functions. This invention enables the developments of new anti-cancer approaches and new anti-cancer medicines. It would create a significant impact on human society.
    Type: Grant
    Filed: May 4, 2016
    Date of Patent: October 18, 2016
    Assignee: Peking University
    Inventors: Rouli Zhou, Genze Shao, Xinrong Liu, Qingyun Zhang, Jingan Rui, Ye Zhang, Yueying Jin, Ming Lin, Sha Zhang
  • HUMAN CANCER-RELATED GENE, ITS ENCODED PRODUCTS AND APPLICATIONS
    Publication number: 20160238608
    Abstract: The invention discloses a human cancer-related gene, LAPTM4B, its encoded products and their applications thereof. This human cancer-related gene provided by this invention comprises one of the following nucleotide sequences: (1) SEQ ID No: 1, SEQ ID No: 2, SEQ ID No: 3, SEQ ID No: 6, or SEQ ID No: 8 in the sequence listings; (2) Polynucleotides that encode the protein sequences of SEQ ID No: 4, SEQ ID No: 5, or SEQ ID No: 7 in the sequence listings; (3) DNA sequences having above 90% homology with the DNA sequences specified by SEQ ID No: 1, SEQ ID No: 2, SEQ ID No: 3, SEQ ID No: 6, or SEQ ID No: 8 in the sequence listings, and these DNA sequences encode the proteins with the same or similar functions. This invention enables the developments of new anti-cancer approaches and new anti-cancer medicines. It would create a significant impact on human society.
    Type: Application
    Filed: May 4, 2016
    Publication date: August 18, 2016
    Inventors: Rouli Zhou, Genze Shao, Xinrong Liu, Qingyun Zhang, Jingan Rui, Ye Zhang, Yueying Jin, Ming Lin, Sha Zhang
  • HUMAN CANCER-RELATED GENE, ITS ENCODED PRODUCTS AND APPLICATIONS
    Publication number: 20120148589
    Abstract: The invention discloses a human cancer-related gene, LAPTM4B, its encoded products and their applications thereof. This human cancer-related gene provided by this invention comprises one of the following nucleotide sequences: (1) SEQ ID No: 1, SEQ ID No: 2, SEQ ID No: 3, SEQ ID No: 6, or SEQ ID No: 8 in the sequence listings; (2) SEQ ID No: 4, SEQ ID No: 5, or SEQ ID No: 7 in the sequence listings which are proteins encoded by the polynucleotides in sequences of SEQ ID No: 1, SEQ ID No: 2, SEQ ID No: 3 and SEQ ID No: 6. (3) Applications of the polynucleotides and polypeptides in the listings in diagnosis and treatments of cancer. This invention enables the developments of new cancer diagnostic markers and new anti-cancer medicines. It would create a significant impact on human society.
    Type: Application
    Filed: February 1, 2011
    Publication date: June 14, 2012
    Inventors: Rouli Zhou, Genze Shao, Xinrong Liu, Qingyun Zhang, Jingan Rui, Ye Zhang, Yueying Jin, Ming Lin, Sha Zhang
  • Antisense and pretargeting optical imaging
    Publication number: 20110158913
    Abstract: The present invention relates, in part, to detectably labeled oligomer duplexes and their use in optical imaging, including, in vivo optical imaging. The invention includes methods of optical imaging including in vivo pretargeting methods and in vivo antisense optical imaging methods.
    Type: Application
    Filed: January 18, 2008
    Publication date: June 30, 2011
    Applicant: University of Massachusetts
    Inventors: Don Hnatowich, Kayoko Nakamura, Yi Wang, Xinrong Liu, Jiang He, Surong Zhang, Mary Rusckowski
  • Human cancer-relating genes, the products encoded thereby and applications thereof
    Patent number: 7910711
    Abstract: The invention discloses a human cancer-related gene, LAPTM4B, its encoded products and their applications thereof. This human cancer-related gene provided by this invention comprises one of the following nucleotide sequences: (1) SEQ ID No: 1, SEQ ID No: 2, SEQ ID No: 3, SEQ ID No: 6, or SEQ ID No: 8 in the sequence listings; (2) Polynucleotides that encode the protein sequences of SEQ ID No: 4, SEQ ID No: 5, or SEQ ID No: 7 in the sequence listings; (3) DNA sequences having above 90% homology with the DNA sequences specified by SEQ ID No: 1, SEQ ID No: 2, SEQ ID No: 3, SEQ ID No: 6, or SEQ ID No: 8 in the sequence listings, and these DNA sequences encode the proteins with the same or similar functions. This invention enables the developments of new anti-cancer approaches and new anti-cancer medicines. It would create a significant impact on human society.
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: March 22, 2011
    Assignee: Peking University
    Inventors: Rouli Zhou, Genze Shao, Xinrong Liu, Qingyun Zhang, Jingan Rui, Ye Zhang, Yueying Jin, Ming Lin, Sha Zhang
  • Human cancer-relating genes, the products encoded thereby and applications thereof
    Publication number: 20070026395
    Abstract: The invention discloses a human cancer-related gene, LAPTM4B, its encoded products and their applications thereof. This human cancer-related gene provided by this invention comprises one of the following nucleotide sequences: (1) SEQ ID No: 1, SEQ ID No: 2, SEQ ID No: 3, SEQ ID No: 6, or SEQ ID No: 8 in the sequence listings; (2) Polynucleotides that encode the protein sequences of SEQ ID No: 4, SEQ ID No: 5, or SEQ ID No: 7 in the sequence listings; (3) DNA sequences having above 90% homology with the DNA sequences specified by SEQ ID No: 1, SEQ ID No: 2, SEQ ID No: 3, SEQ ID No: 6, or SEQ ID No: 8 in the sequence listings, and these DNA sequences encode the proteins with the same or similar functions. This invention enables the developments of new anti-cancer approaches and new anti-cancer medicines. It would create a significant impact on human society.
    Type: Application
    Filed: December 24, 2003
    Publication date: February 1, 2007
    Inventors: Rouli Zhou, Genzo Shao, Xinrong Liu, Qingyun Zhang, Jingan Rui, Ye Zhang, Yueying Jin, Ming Lin, Sha Zhang