Abstract: A viral exposure signature (VES) that can identify early stage, pre-symptomatic hepatocellular carcinoma (HCC) among at-risk patients is described. The VES was developed using serological profiling and synthetic virome technology to identify unique viral peptide epitopes corresponding to 61 viral species. Methods of identifying a subject with early stage (pre-symptomatic) HCC using the VES are described.

Abstract: This disclosure provides methods for predicting the likelihood that a hepatocellular carcinoma (HCC) will respond to transcatheter arterial chemoembolization (TACE) using a gene signature of 14 or 15 genes. Also provided are nucleic acid probes and kits for detecting the gene signature.

Abstract: A card edge connector with an insulative housing includes opposite longitudinal side walls along a longitudinal direction with a receiving slot therebetween in a transverse direction. Each side wall forms a plurality of passageways. A plurality of contacts are respectively received within the corresponding passageways. Each contact includes a retaining section, a contacting section extending from the retaining section into the receiving slot, and a leg extending downwardly from the retaining section out of the housing. Each contact is further equipped with an auxiliary spring beam with an additional contacting section extending into the receiving slot. The contacts are initially linked to a single contact carrier strip so as to be simultaneously inserted into the corresponding passageways, respectively.

Abstract: A card edge connector includes an elongated insulative housing, a number of terminals retained to the housing, and a metallic member formed integrally with the housing via an insert-molding process. The housing includes two lengthwise walls, a central slot defining by the two lengthwise walls, and two protrusions located at two opposite ends of the two lengthwise walls. The protrusions protrude upwardly out of an upper surface of the lengthwise walls. The metallic member includes two main portions retained respectively in the two lengthwise walls and a pair of connecting portions connecting therebetween. The connecting portions are located at the bottom of the metallic member.

Abstract: This disclosure provides methods for predicting the likelihood that a hepatocellular carcinoma (HCC) will respond to transcatheter arterial chemoembolization (TACE) using a gene signature of 14 or 15 genes. Also provided are nucleic acid probes and kits for detecting the gene signature.

Abstract: According to various examples, a first resolution of original display data and a second resolution of a text display may be obtained. In response to a determination that the second resolution is smaller than the first resolution, the original display data may be searched for a relocation area and a bland area. The relocation area may include valid pixels not capable of being displayed on the text display. The blank area may not include valid pixels and may be capable of being displayed on the text display. The blank area may be used to accommodate the relocation area within the text display to generate reconstructed display data, and the reconstructed display data may be outputted to the text display.

Abstract: A card edge connector with an insulative housing includes opposite longitudinal side walls along a longitudinal direction with a receiving slot therebetween in a transverse direction. Each side wall forms a plurality of passageways. A plurality of contacts are respectively received within the corresponding passageways. Each contact includes a retaining section, a contacting section extending from the retaining section into the receiving slot, and a leg extending downwardly from the retaining section out of the housing. Each contact is further equipped with an auxiliary spring beam with an additional contacting section extending into the receiving slot. The contacts are initially linked to a single contact carrier strip so as to be simultaneously inserted into the corresponding passageways, respectively.

Abstract: An electrical card edge connector for receiving an electronic card with a bottom notch therein, includes an insulative housing, a plurality of terminals and an alignment key. The housing includes two opposite side walls, a bottom wall and a central slot among the side walls and the bottom wall. The terminals are disposed in the corresponding side walls and extend into the central slot for mating with the electronic card. The alignment key includes a body received within the central slot, a pair of extension sections covering the two side walls, and a pair of securing sections attached to the bottom wall wherein the body is adapted to be received within the bottom notch of the electronic card.

Abstract: According to various examples, a first resolution of original display data and a second resolution of a text display may be obtained. In response to a determination that the second resolution is smaller than the first resolution, the original display data may be searched for a relocation area and a bland area. The relocation area may include valid pixels not capable of being displayed on the text display. The blank area may not include valid pixels and may be capable of being displayed on the text display. The blank area may be used to accommodate the relocation area within the text display to generate reconstructed display data, and the reconstructed display data may be outputted to the text display.

Abstract: A card edge connector includes an insulative housing, a plurality of conductive terminals and a pair of metal members. The insulative housing defines two side walls extending in a longitudinal direction and a central slot disposed between said two side walls, the conductive terminals are disposed in the insulative housing and protruding into the central slot, the pair of metal members enclose the insulative housing, wherein each side wall defines an embedded groove recessed from a top surface thereof and extending along the side wall in said longitudinal direction, each metal member defines a main portion enclosing an outside of the side wall and a bending portion bending from an upside thereof, the bending portion is retained in the embedded groove to provide a stability for the card edge connector.

Abstract: A card edge connector includes an elongated insulative housing, a number of terminals retained to the housing, and a metallic member formed integrally with the housing via an insert-molding process. The housing includes two lengthwise walls, a central slot defining by the two lengthwise walls, and two protrusions located at two opposite ends of the two lengthwise walls. The protrusions protrude upwardly out of an upper surface of the lengthwise walls. The metallic member includes two main portions retained respectively in the two lengthwise walls and a pair of connecting portions connecting therebetween. The connecting portions are located at the bottom of the metallic member.

Abstract: A card edge connector includes an elongated insulative housing forming a central slot with two rows of terminals disposed by two sides of the central slot and retained in the housing. The housing includes two opposite lengthwise walls and two end walls connected to two opposite ends of the corresponding lengthwise walls, and a bottom wall linked to both the lengthwise walls and the end walls below the central slot. A removable key element is assembled to the two lengthwise walls and intersecting with the central slot. A receiving cavity is formed in the bottom wall to receive a light emitting device located under the key element and mounted upon the printed circuit board on which the connector is seated.

Abstract: An electrical card edge connector for receiving an electronic card with a bottom notch therein, includes an insulative housing, a plurality of terminals and an alignment key. The housing includes two opposite side walls, a bottom wall and a central slot among the side walls and the bottom wall. The terminals are disposed in the corresponding side walls and extend into the central slot for mating with the electronic card. The alignment key includes a body received within the central slot, a pair of extension sections covering the two side walls, and a pair of securing sections attached to the bottom wall wherein the body is adapted to be received within the bottom notch of the electronic card.

Abstract: A card edge connector includes an insulative housing, a plurality of conductive terminals and a pair of metal members. The insulative housing defines two side walls extending in a longitudinal direction and a central slot disposed between said two side walls, the conductive terminals are disposed in the insulative housing and protruding into the central slot, the pair of metal members enclose the insulative housing, wherein each side wall defines an embedded groove recessed from a top surface thereof and extending along the side wall in said longitudinal direction, each metal member defines a main portion enclosing an outside of the side wall and a bending portion bending from an upside thereof, the bending portion is retained in the embedded groove to provide a stability for the card edge connector.

Abstract: A card edge connector includes an elongated insulative housing forming a central slot with two rows of terminals disposed by two sides of the central slot and retained in the housing. The housing includes two opposite lengthwise walls and two end walls connected to two opposite ends of the corresponding lengthwise walls, and a bottom wall linked to both the lengthwise walls and the end walls below the central slot. A removable key element is assembled to the two lengthwise walls and intersecting with the central slot. A receiving cavity is formed in the bottom wall to receive a light emitting device located under the key element and mounted upon the printed circuit board on which the connector is seated.

Abstract: Methods are disclosed for determining the prognosis of a subject with an adenocarcinoma in an organ, such as the lung. The methods can include quantitating expression of a plurality of cytokines of interest, such as IL-1a, IL-1b, IL-2, IL-8, IL-10, IL-12, IL-15, IFN-? and TNF-a in the adenocarcinoma and in non-cancerous tissue in the organ. Altered expression of IL-1a, IL-1b, IL-2, IL-8, IL-10, IL-12, IL-15, IFN-? and TNF-a in the adenocarcinoma as compared to a control and in non-cancerous tissue in the organ as compared to a control determines the prognosis for the subject. Methods for determining if a therapeutic agent is effective as an anti-cancer agent are also disclosed.

Abstract: Disclosed herein is a driver gene signature for predicting survival in patients with solid tumors, such as hepatocellular carcinoma (HCC) and breast cancer. The gene signature includes ten tumor-associated genes, SH2D4A, CCDC25, ELP3, DLC1, PROSC, SORBS3, HNRPD, PAQR3, PHF17 and DCK. A decrease in DNA copy number or mRNA expression of SH2D4A, CCDC25, ELP3, DLC1, PROSC and SORBS3 in solid tumors is associated with a poor prognosis, while a decrease in DNA copy number or mRNA expression of HNRPD, PAQR3, PHF17 and DCK in solid tumors is associated with a good prognosis. Methods of predicting the prognosis of a patient diagnosed with HCC or breast cancer by detecting expression of one of more tumor-associated genes, and methods of treating a patient diagnosed with HCC or breast cancer by administering an agent that alters expression or activity of one or more of the disclosed tumor-associated genes, are described.

Abstract: A card edge connector (100) includes an insulative housing, a set of contacts (2) retained in the insulative housing and an ejector (3). The insulative housing has a central slot (12) and one tower portion (13) having a receiving slot (135). The contacts protrude into the central slot. The ejector has a main portion (31) received in the receiving slot, an ejecting portion (34) extending from a lower end (35) of the main portion, a locking portion (32) extending inwardly from an upper end of the main portion, and a lever portion (37) extending outwardly from the upper end of the main portion. The locking portion has a pair of vertical portions (324), and a transverse portion (323). The transverse portion connects the vertical portions and divides the vertical portions into upper and lower retaining parts.

Abstract: Disclosed herein is a driver gene signature for predicting survival in patients with solid tumors, such as hepatocellular carcinoma (HCC) and breast cancer. The gene signature includes ten tumor-associated genes, SH2D4A, CCDC25, ELP3, DLC1, PROSC, SORBS3, HNRPD, PAQR3, PHF17 and DCK. A decrease in DNA copy number or mRNA expression of SH2D4A, CCDC25, ELP3, DLC1, PROSC and SORBS3 in solid tumors is associated with a poor prognosis, while a decrease in DNA copy number or mRNA expression of HNRPD, PAQR3, PHF17 and DCK in solid tumors is associated with a good prognosis. Methods of predicting the prognosis of a patient diagnosed with HCC or breast cancer by detecting expression of one of more tumor-associated genes, and methods of treating a patient diagnosed with HCC or breast cancer by administering an agent that alters expression or activity of one or more of the disclosed tumor-associated genes, are described.

Abstract: A card edge connector (100) includes an elongated housing (1) and a plurality of contacts (2). The housing (1) has two side walls (103) and a central slot (109) between the two side walls (103) for receiving a memory module (9). The card edge connector (100) includes a latching mechanism (5) mounted on the two side walls (103) for resisting the memory module (9) downwardly. The latching mechanism (5) can prevent the memory module (9) from moving upwardly, thereby the memory module (9) could be stably connected with the card edge connector (100).