Abstract: A tin-titanium-silicon molecular sieve, a preparation method and an application thereof are provided. The electron binding energy of framework tin active centers in the tin-titanium-silicon molecular sieve is 488.5 eV or less. In the tin-titanium-silicon molecular sieve, the molar ratio of titanium to silicon is preferably 0.005-0.03, and the molar ratio of tin to silicon is preferably 0.005-0.025. The tin-titanium-silicon molecular sieve of the invention has more catalytic active centers, a lower electron binding energy of framework tin active centers, and an excellent catalytic performance.

Abstract: A drug IC50 deep learning model prediction method based on molecular structure and gene expression includes establishing a deep learning model to predict drug IC50 in different cell lines; predicting the drug IC50 in different cell lines based on the deep learning model. Also disclosed are prediction systems, electronic devices and computer readable storage media, which use grammar variational autoencoder to encode the chemical molecular formula of drugs and use autoencoder to encode cell line expression data, predict the drug IC50 in different cell lines through neural network methods, and predict the drug IC50 values of drugs in different types of cancer cell lines directly through the molecular information of drugs, which can reduce the investment of funds and time in preclinical development. Applying the model to patients helps screen out the applicable population of drugs, reduces unnecessary clinical trials, and improves the success rate of clinical trials.

Abstract: The present invention relates to a titanium silicalite molecular sieve, wherein the crystal grain of the titanium silicalite molecular sieve has a ratio of (surface Si/Ti ratio):(bulk Si/Ti ratio) being larger than 1.1 and less than 5.

Abstract: The present invention relates to a full-Si molecular sieve, wherein the full-Si molecular sieve has a Q4/Q3 of (10-90):1 wherein Q4 is the peak strength at the chemical shift of ?112±2 ppm in the 29Si NMR spectrum of the full-Si molecular sieve, expressed as the peak height relative to the base line; and Q3 is the peak strength at the chemical shift of ?103±2 ppm in the 29Si NMR spectrum of the full-Si molecular sieve, expressed as the peak height relative to the base line.

Abstract: The present invention relates to a full-Si molecular sieve, wherein the full-Si molecular sieve has a Q4/Q3 of (10-90):1.

Abstract: The present invention relates to a titanium silicalite molecular sieve, wherein the crystal grain of the titanium silicalite molecular sieve has a ratio of (surface Si/Ti ratio):(bulk Si/Ti ratio) being larger than 1.1 and less than 5.