Patents by Inventor Xinying Zhang

Xinying Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7382840
    Abstract: A method for antenna subset selection by joint processing in RF and baseband in a multi-antenna systems. Lt input data streams are generated in a transmitter for either diversity transmission or multiplexing transmission. These streams are modulated to RF signals. These signals are switched to the t branches associated with the t transmit antennas, and a phase-shift transformation is applied to the RF signals by a t×t matrix multiplication operator ?1, whose output are t?Lt RF signals. These signals are transmitted over a channel by t antennas. The transmitted signals are received by r antennas in a receiver. A phase-shift transformation is applied to the r RF signals by a r×r matrix multiplication operator ?2. Lr branches of these phase shifted streams are demodulated and further processed in baseband to recover the input data streams.
    Type: Grant
    Filed: July 29, 2003
    Date of Patent: June 3, 2008
    Assignee: Mitsubishi Electric Research Laboratories, Inc.
    Inventors: Andreas Molisch, Sun Yuan Kung, Xinying Zhang, Jinyun Zhang
  • Publication number: 20080021044
    Abstract: The present invention is directed to N-[2-[[(diaminomethylene)amino]oxy]ethyl]-3-[(2,2-difluoro-2-phenylethyl)amino]-6-methyl-s-oxo-1(2H)-pyrazineacetamide, pharmaceutical compositions containing said compound and methods of treatment comprising inhibiting a serine protease using said compound. The present invention is further directed to a process for the preparation of the N-[2-[[(diaminomethylene)amino]oxy]ethyl]-3-[(2,2-difluoro-2-phenylethyl)amino]-6-methyl-2-oxo-1(2H)-pyrazineacetamide as a free base. The present invention is further directed to a process for the preparation of pharmaceutically acceptable salts of N-[2-[[(aminoiminomethyl)amino]oxy]ethyl]-3-[(2,2-difluoro-2-phenylethyl)amino]-6-methyl-2-oxo-1(2H)-pyrazineacetamide.
    Type: Application
    Filed: May 21, 2007
    Publication date: January 24, 2008
    Inventors: Mitul Patel, Christopher Nilsen, Mayra Reyes, Michael Humora, Yun Qian, Fuqiang Liu, Xini Zhang, Kirk Sorgi
  • Patent number: 6999538
    Abstract: A source signal transmitted through multiple channels having space, time and frequency diversities to generate multiple received signals is recovered by an iterative associative memory model with dynamic maximum likelihood estimation. A current symbol vector representing the multiple received signals is projected to a net-vector using a linear matrix operation with a weight matrix W. The weight matrix is obtained by a singular value decomposition of an input symbol sequence. The net-vector is mapped to a nearest symbol vector using a non-linear operation with an activation function. The projecting and mapping steps are repeated until the nearest symbol vector converges to a valid symbol vector representing the source signal.
    Type: Grant
    Filed: September 10, 2001
    Date of Patent: February 14, 2006
    Assignee: Mitsubishi Electric Research Laboratories, Inc.
    Inventors: Sun Yuan Kung, Xinying Zhang, Jinyun Zhang
  • Publication number: 20050025271
    Abstract: A method for antenna subset selection by joint processing in RF and baseband in a multi-antenna systems. Lt input data streams are generated in a transmitter for either diversity transmission or multiplexing transmission. These streams are modulated to RF signals. These signals are switched to the t branches associated with the t transmit antennas, and a phase-shift transformation is applied to the RF signals by a t×t matrix multiplication operator ?1, whose output are t?Lt RF signals. These signals are transmitted over a channel by t antennas. The transmitted signals are received by r antennas in a receiver. A phase-shift transformation is applied to the r RF signals by a r×r matrix multiplication operator ?2. Lr branches of these phase shifted streams are demodulated and further processed in baseband to recover the input data streams.
    Type: Application
    Filed: July 29, 2003
    Publication date: February 3, 2005
    Inventors: Andreas Molisch, Sun Kung, Xinying Zhang, Jinyun Zhang
  • Publication number: 20030223516
    Abstract: A receiver in a multiple-input-multiple-output, frequency-selective fading wireless communication systems sequentially recovers multiple data stream. A next input stream, having a highest signal-to-noise ratio is selected. The selected input stream is equalized, detected and decoded. The decoded data stream is then substracted from the data streams, and the selecting, equalizing, detecting and decoding, and subtracting is repeated until all of the data streams have been decoded.
    Type: Application
    Filed: May 28, 2002
    Publication date: December 4, 2003
    Inventors: Xinying Zhang, Sun Yuan Kung, Jinyun Zhang, Giovanni Vannucci
  • Publication number: 20030048861
    Abstract: A source signal transmitted through multiple channels having space, time and frequency diversities to generate multiple received signals is recovered by an iterative associative memory model with dynamic maximum likelihood estimation. A current symbol vector representing the multiple received signals is projected to a net-vector using a linear matrix operation with a weight matrix W. The weight matrix is obtained by a singular value decomposition of an input symbol sequence. The net-vector is mapped to a nearest symbol vector using a non-linear operation with an activation function The projecting and converting steps are repeated until the nearest symbol vector converges to a valid symbol vector representing the source signal.
    Type: Application
    Filed: September 10, 2001
    Publication date: March 13, 2003
    Inventors: Sun Yuan Kung, Xinying Zhang, Jinyun Zhang
  • Patent number: 6410598
    Abstract: The present invention relates generally to the non-enzymatic glycosylation of amyloidogenic proteins and the consequent formation of advanced glycosylation endproducts (AGEs). It has been found that formation of AGE-amyloidogenic proteins can enhance amyloidosis. The invention further relates to compositions and methods for the prevention and treatment of amyloidosis associated with amyloid diseases, particularly neurodegenerative disease and Type II diabetes, and more particularly Alzheimer's disease. In a specific example, aggregation of an amyloidogenic peptide, &bgr;AP, is enhanced by the glycosylation reaction of &bgr;AP to form AGE-&bgr;AP as defined herein. Accordingly, the invention extends to a method for modulating the in vivo aggregation of amyloid polypeptides and associated amyloidosis by controlling the formation and presence of AGE-amyloid polypeptide.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 25, 2002
    Inventors: Michael P. Vitek, Anthony Cerami, Richard J. Bucala, Peter C. Ulrich, Helen Vlassara, Xini Zhang
  • Patent number: 5948896
    Abstract: A process for the preparation of 13-deoxy deoxyanthracycline derivatives.
    Type: Grant
    Filed: August 13, 1997
    Date of Patent: September 7, 1999
    Assignee: GEM Pharmaceuticals
    Inventor: Xini Zhang
  • Patent number: 5942605
    Abstract: 5-imino-13-deoxy anthracycline derivatives, medical uses of 5-imino-13-deoxy anthracycline derivatives and methods for preparing 5-imino-13-deoxy anthracycline derivatives.
    Type: Grant
    Filed: March 3, 1998
    Date of Patent: August 24, 1999
    Assignee: GEM Pharmaceuticals, Inc.
    Inventors: Xini Zhang, Richard D. Olson
  • Patent number: 5935927
    Abstract: The present invention relates generally to methods and compositions for treating amyloidogenic diseases such as Alzheimer's disease and the development of type II diabetes, in which deposition of amyloid in organs such as the brain and pancreas interfere with neurological function and insulin release, respectively. The methods and compositions are directed toward increasing the activity of scavenger cells within the body at recognizing and removing amyloid deposits from affected tissues and organs. Scavenger cells may be targeted to amyloid deposits by means of spontaneously-occurring chemical modifications called advanced glycosylation endproducts (AGEs). Compositions are described which increase scavenger cell activity towards AGE-modified amyloid.
    Type: Grant
    Filed: August 10, 1996
    Date of Patent: August 10, 1999
    Assignee: The Picower Institute For Medical Research
    Inventors: Michael P. Vitek, Anthony Cerami, Richard J. Bucala, Peter C. Ulrich, Helen Vlassara, Xini Zhang
  • Patent number: 5814664
    Abstract: The present invention relates to advanced glycosylation endproducts, and particularly to the use of novel cyclopentenone aminoreductones, 3-alkylamino-2 -hydroxy-4-hydroxymethyl-2-cyclopenten-1-ones. Such AGEs can be used in various diagnostic and therapeutic methods.
    Type: Grant
    Filed: June 23, 1997
    Date of Patent: September 29, 1998
    Assignee: Picower Institute for Medical Research
    Inventors: Peter C. Ulrich, Xini Zhang
  • Patent number: 5688653
    Abstract: The present invention relates to advanced glycosylation endproducts (AGEs), and particularly to novel cyclopentenone aminoreductones, 3-alkylamino-2-hydroxy-4-hydroxymethyl-2-cyclopenten-1-ones. Such AGEs can be used in various diagnostic and therapeutic methods.
    Type: Grant
    Filed: June 27, 1996
    Date of Patent: November 18, 1997
    Assignee: The Picower Institute for Medical Research
    Inventors: Peter C. Ulrich, Xini Zhang