Abstract: Use of a compound of Formula I for treating atherosclerosis and related diseases, disorders and conditions in a subject in need of such treatment, wherein the subject in need of such treatment is a subject carrying one or more genetic mutations in ALPK1.

Abstract: The present invention discloses a method for treating ROSAH syndrome, specifically relates to a method for inhibiting ALPK1 or ALPK1[T237M]. The ALPK1 inhibitor has excellent pharmacokinetic properties, and has the potential to serve as a precision-targeted drug for the treatment of ROSAH syndrome.

Abstract: A method for filtering a food product, including the steps of: (a) providing a food product, wherein the food product comprises a fermentation liquid derived from an edible nitrate containing plant; (b) passing the food product through a first filter; (c) passing the food product through a second filter; and (d) optionally controllably spray drying the food product at high-temperature.

Abstract: A high efficiency fermentation process/method for converting nitrate to nitrite in food products, comprising the steps of: (a) providing a food product, wherein the food product comprises a fermentable liquid medium obtained and/or derived from an edible nitrate containing plant; and (b) controllably fermenting the food product such that nitrate to nitrite conversion results in nitrite concentration levels greater than approximately 3% by weight.

Abstract: Provided herein are methods for inhibiting ALPK1 kinase activity using a compound of Formula I, and compositions and methods for therapy, for example in treating Kawasaki Disease.

Abstract: Provided herein are compounds of Formula (I) or (II) and related compositions and methods for their use as inhibitors of alpha-kinase 1 (ALPK1) and in treating Kawasaki Disease.

Abstract: A method for drying a food product that results in a highly homogenous, low-moisture content powder having significantly reduced particle size without materially altering the flavor profile and/or the nutritional profile of the food product, including the steps of: (1) providing a food product, wherein the food product comprises a fermentation liquid; (2) optionally filtering the food product; and (3) controllably spray drying the food product at high-temperature.

Abstract: A method for pasteurizing/sanitizing/sterilizing a food product to reduce the microbial load thereof, including the steps of: (1) providing a food product, wherein the food product comprises a plant seed and/or an aqueous plant seed medium; (2) optionally fermenting the food product; (3) controllably exposing the food product to ultra-high-temperature processing for a period of time; and (4) at least one of pasteurizing, sanitizing, and sterilizing the food product without materially altering the flavor profile and/or the nutritional profile of the food product.

Abstract: Provided are compounds of Formula (I) or (II) and related compositions and methods for their use as inhibitors of alpha-kinase 1 (ALPK1).

Abstract: Provided are compounds of Formula I, compositions and methods for their use as inhibitors of alpha-kinase 1 (ALPK1).

Abstract: A method, system and computer program product for container image migration service is provided. The method comprises identifying a latest version of a first customer container image stored in a container image repository. The method further comprises determining the latest version of the first customer container image is a migration image from a last version of the first customer container image; determining a set of commands in the Docker file of the last version of the first customer container image that have migrated to a corresponding set of commands in the Docker file of the migration image; identifying a latest version of a second customer container image having at least one Docker file command in common with at least one command in the set of commands; and recommending imminent migration of the second customer container image to include migration of the at least one Docker file command.

Abstract: In an approach, a processor creates a local first Pod API object in a first lower Kubernetes cluster based on a first Pod API object in an upper Kubernetes cluster, where: the local first Pod API object includes internal and external network descriptions for a Pod described in the local first Pod API object, and the upper cluster manages the first and second lower Kubernetes cluster. A processor adds an annotation for the Pod to the local first Pod API object and the first Pod API object. A processor creates a local endpoint API object in the first lower cluster based on an endpoint API object in the upper cluster and annotations of Pods in the upper cluster. A processor redirects the first request to the endpoint of the second Pod described in the local endpoint API object.

Abstract: An ultrasonic transducer employing a meta slab includes a piezoelectric body configured to generate elastic waves; a meta slab connected to the piezoelectric body and configured to induce elastic wave mode conversion resonance with respect to the elastic waves incident on the meta slab; and a wedge connected to the meta slab, attached to an external surface of a pipe, and configured to transmit the elastic waves having passed through the meta slab to the pipe. The meta slab includes an anisotropic medium and a thickness of the meta slab satisfies the equation as follows: d=m·nFS·?FS/4, d=m·nSS·?SS/4, nSS/2?nFS/2=odd. Thus, highly-efficient flow velocity measurement is possible.

Abstract: A method, system and computer program product for container image migration service is provided. The method comprises identifying a latest version of a first customer container image stored in a container image repository. The method further comprises determining the latest version of the first customer container image is a migration image from a last version of the first customer container image; determining a set of commands in the Docker file of the last version of the first customer container image that have migrated to a corresponding set of commands in the Docker file of the migration image; identifying a latest version of a second customer container image having at least one Docker file command in common with at least one command in the set of commands; and recommending imminent migration of the second customer container image to include migration of the at least one Docker file command.

Abstract: A downlink Hybrid Automatic Repeat Request (HARQ) feedback method is provided, and includes: determining whether a currently used frame structure needs to be reconfigured; determining an uplink subframe for implementing a downlink HARQ feedback corresponds to each downlink subframe according to the currently used frame structure, when no reconfiguration is needed; determining an uplink subframe for implementing the downlink HARQ feedback corresponds to each downlink subframe in a last radio frame before the reconfiguration time point, when the reconfiguration is needed, according to a first frame structure used before a reconfiguration time point and a second frame structure to be used; determining an uplink subframe for implementing the downlink HARQ feedback corresponds to each downlink subframe in a last radio frame before the reconfiguration time point; when receiving downlink data sent by a base station on any downlink subframe, sending a HARQ feedback message for the downlink data.

Abstract: An ultrasonic transducer employing a meta slab includes a piezoelectric body configured to generate elastic waves; a meta slab connected to the piezoelectric body and configured to induce elastic wave mode conversion resonance with respect to the elastic waves incident on the meta slab; and a wedge connected to the meta slab, attached to an external surface of a pipe, and configured to transmit the elastic waves having passed through the meta slab to the pipe. The meta slab includes an anisotropic medium and a thickness of the meta slab satisfies the equation as follows: d=m·nFS·?FS/4, d=m·nSS·?SS/4, nSS/2?nFS/2=odd. Thus, highly-efficient flow velocity measurement is possible.

Abstract: The present disclosure provides an uplink scheduling method in an unlicensed frequency band based on a dynamic frame structure, an uplink scheduling device and a base station. Each frame structure includes uplink and downlink subframes, and same type of a subframe continuity settings, the method includes: determining whether a currently used frame structure in an unlicensed frequency band needs to be reconfigured; when reconfiguration is not required, determining an uplink subframe to be scheduled on each downlink subframe according to the currently used frame structure; when reconfiguration is required, determining an uplink subframe to be scheduled on each downlink subframe in a last radio frame before a reconfiguration time point according to a first frame structure used before the reconfiguration time point and a second frame structure to be used; transmitting a scheduling instruction for the uplink subframe to be scheduled on each downlink subframe.

Abstract: This disclosure provides a computer-implemented method for debugging a program including a SQL statement. The method comprises indicating one or more first positions of source code of the program. Each of the one or more first positions corresponds to a fragment of the SQL statement at which a breakpoint can be set. The method further comprises receiving an input of setting breakpoint at one of the one or more first positions. The method further comprises presenting an execution context generated in response to execution of the program reaching a breakpoint set based on the input.

Abstract: This disclosure provides a computer-implemented method for debugging a program including a SQL statement. The method comprises indicating one or more first positions of source code of the program. Each of the one or more first positions corresponds to a fragment of the SQL statement at which a breakpoint can be set. The method further comprises receiving an input of setting breakpoint at one of the one or more first positions. The method further comprises presenting an execution context generated in response to execution of the program reaching a breakpoint set based on the input.

Abstract: A downlink Hybrid Automatic Repeat Request (HARQ) feedback method is provided, and includes: determining whether a currently used frame structure needs to be reconfigured; determining an uplink subframe for implementing a downlink HARQ feedback corresponds to each downlink subframe according to the currently used frame structure, when no reconfiguration is needed; determining an uplink subframe for implementing the downlink HARQ feedback corresponds to each downlink subframe in a last radio frame before the reconfiguration time point, when the reconfiguration is needed, according to a first frame structure used before a reconfiguration time point and a second frame structure to be used; determining an uplink subframe for implementing the downlink HARQ feedback corresponds to each downlink subframe in a last radio frame before the reconfiguration time point; when receiving downlink data sent by a base station on any downlink subframe, sending a HARQ feedback message for the downlink data.