Patents by Inventor Xiongwei Shi

Xiongwei Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of CCR5 receptor antagonists
    Patent number: 7728135
    Abstract: The present invention is directed to the synthesis of 4-[4-[(R)-[1-[cyclopropylsulfonyl)-4-piperidinyl](3-fluorophenyl)methyl]-3(S)-methyl-1-piperazinyl]-1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-methylpiperidine], and intermediates therefor from readily available starting materials by a novel route.
    Type: Grant
    Filed: January 5, 2006
    Date of Patent: June 1, 2010
    Assignee: Schering Corporation
    Inventors: Xiongwei Shi, Man Zhu, William Leong, Vilas Dahanukar, Ilia A. Zavialov, Cecelia Proietti, Shannon Zhao, Hong-Chang Lee, Yi Liu, Hoa N. Nguyen, Wenxue Wu, Bosco D'Sa, Feng Liang, Loc Thanh Tran
  • SYNTHESIS OF CCR5 RECEPTOR ANTAGONISTS
    Publication number: 20100036125
    Abstract: The present invention is directed to the synthesis of 4-[4-[(R)-[1-[cyclopropylsulfonyl)-4-piperidinyl](3-fluorophenyl)methyl]-3(S)-methyl-1-piperazinyl]-1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-methylpiperidine], and intermediates therefor from readily available starting materials by a novel route.
    Type: Application
    Filed: October 16, 2009
    Publication date: February 11, 2010
    Inventors: Xiongwei Shi, Man Zhu, William Leong, Vilas Dahanukar, Ilia A. Zavialov, Cecilia Proietti, Shannon Zhao, Hong-Chang Lee, Yi Liu, Hoa N. Nguyen, Wenxue Wu, Bosco D'Sa, Feng Liang, Loc Thanh Tran
  • Synthesis of CCR5 antagonists
    Publication number: 20060258863
    Abstract: The present invention is directed to the synthesis of 4-[4-[(R)-[1-[cyclopropylsulfonyl)-4-piperidinyl](3-fluorophenyl)methyl]-3(S)-methyl-1-piperazinyl]-1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-methylpiperidine], and intermediates therefor from readily available starting materials by a novel route.
    Type: Application
    Filed: January 5, 2006
    Publication date: November 16, 2006
    Inventors: Xiongwei Shi, Man Zhu, William Leong, Vilas Dahanukar, Ilia Zavialov, Cecilia Proletei, Shannon Zhao, Hong-Chang Lee, Yi Liu, Hoa Nguyen, Wenxue Wu, Bosco D'Sa, Feng Liang, Loc Tran
  • Synthesis of piperidine and piperazine compounds as CCR5 antagonists
    Patent number: 6992189
    Abstract: In its several embodiments, this invention discloses novel processes to prepare the compounds of formula II and formula IV:
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: January 31, 2006
    Assignee: Schering Corporation
    Inventors: William Leong, Minzhang Chen, Bosco A. D'sa, Man Zhu, Tong Xiao, Xiongwei Shi, Suhan Tang, Dinesh Gala, Andrew J. Goodman, Christopher M. Nielsen, Gary M. Lee, Juan A. Gamboa, Andrew D. Jones
  • Synthesis of piperidine and piperazine compounds as CCR5 antagonists
    Publication number: 20050187248
    Abstract: In its several embodiments, this invention discloses novel processes to prepare the compounds of formula II and formula IV:
    Type: Application
    Filed: March 24, 2005
    Publication date: August 25, 2005
    Inventors: William Leong, Minzhang Chen, Bosco D'sa, Man Zhu, Tong Xiao, Xiongwei Shi, Suhan Tang, Dinesh Gala, Andrew Goodman, Christopher Nielsen, Gary Lee, Juan Gamboa, Andrew Jones
  • Synthesis of piperidine and piperazine compounds as CCR5 antagonists
    Publication number: 20040024217
    Abstract: In its several embodiments, this invention discloses novel processes to prepare the compounds of formula II and formula IV: 1
    Type: Application
    Filed: March 27, 2003
    Publication date: February 5, 2004
    Applicant: Schering Corporation
    Inventors: William Leong, Minzhang Chen, Bosco A. D'sa, Man Zhu, Tong Xiao, Xiongwei Shi, Suhan Tang, Dinesh Gala, Andrew J. Goodman, Christopher M. Nielsen, Gary M. Lee, Juan A. Gamboa, Andrew D. Jones
  • Farnesyl protein transferase inhibitors
    Patent number: 6528523
    Abstract: The present invention describes compounds useful for the inhibition of Farnesyl Protein Transferase. This invention also discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with FPT.
    Type: Grant
    Filed: November 27, 2001
    Date of Patent: March 4, 2003
    Assignee: Schering Corporation
    Inventors: F. George Njoroge, Bancha Vibulbhan, Viyyoor M. Girijavallabhan, Xiongwei Shi
  • Novel farnesyl protein transferase inhibitors
    Publication number: 20020115679
    Abstract: The present invention describes compounds useful for the inhibition of Farnesyl Protein Transferase. This invention also discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with FPT.
    Type: Application
    Filed: November 27, 2001
    Publication date: August 22, 2002
    Inventors: F. George Njoroge, Bancha Vibulbhan, Viyyoor M. Girijavallabhan, Xiongwei Shi