Patents by Inventor Xiongwei Yan

Xiongwei Yan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230124451
    Abstract: Disclosed is a probe for use in biological assays. The probe includes a fluorescent dye bound to a quencher compound through an oligonucleotide linker. Also disclosed are methods of using the probe, such as for a polymerase chain reaction (PCR), such as in a quantitative PCR reaction (qPCR), as well as kits including the probe.
    Type: Application
    Filed: December 7, 2022
    Publication date: April 20, 2023
    Inventors: Khairuzzaman Bashar MULLAH, Brian EVANS, Scott C. BENSON, Chu-An CHANG, Xiongwei YAN
  • Patent number: 11535885
    Abstract: Disclosed is a probe for use in biological assays. The probe includes a fluorescent dye bound to a quencher compound through an oligonucleotide linker. Also disclosed are methods of using the probe, such as for a polymerase chain reaction (PCR), such as in a quantitative PCR reaction (qPCR), as well as kits including the probe.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: December 27, 2022
    Inventors: Khairuzzaman Bashar Mullah, Brian Evans, Scott C. Benson, Chu-An Chang, Xiongwei Yan
  • Publication number: 20220056041
    Abstract: The present invention is directed to fluorescent rhodamine dyes having spectral properties suited to the creation of multiplex assay systems for use in molecular biology, cell biology and molecular genetics.
    Type: Application
    Filed: December 20, 2019
    Publication date: February 24, 2022
    Inventors: Brian EVANS, Scott BENSON, Khairuzzaman MULLAH, Xiongwei YAN
  • Publication number: 20200407780
    Abstract: Disclosed is a probe for use in biological assays. The probe includes a fluorescent dye bound to a quencher compound through an oligonucleotide linker. Also disclosed are methods of using the probe, such as for a polymerase chain reaction (PCR), such as in a quantitative PCR reaction (qPCR), as well as kits including the probe.
    Type: Application
    Filed: March 1, 2019
    Publication date: December 31, 2020
    Inventors: Khairuzzaman Bashar MULLAH, Brian EVANS, Scott C. BENSON, Chu-An CHANG, Xiongwei YAN
  • Patent number: 10527801
    Abstract: The present disclosure discloses a plug protection cap that includes a main body, a connecting sleeve, and a traction stub. An accommodating cavity is disposed in the main body. An inlet is through the accommodating cavity that is disposed on an end face of one end of the main body. One end of the connecting sleeve detachably sheathes one end that is of the main body and that is away from the inlet, and the other end of the connecting sleeve is connected to one end of the traction stub in a rotatable manner. The present disclosure further discloses an optical fiber connector assembly, a fiber plug, and a network device.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: January 7, 2020
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Xiongwei Yan, Wenxin Wu, Yuliang Wang, Xuesong Huang
  • Publication number: 20190170947
    Abstract: The present disclosure discloses a plug protection cap that includes a main body, a connecting sleeve, and a traction stub. An accommodating cavity is disposed in the main body. An inlet is through the accommodating cavity that is disposed on an end face of one end of the main body. One end of the connecting sleeve detachably sheathes one end that is of the main body and that is away from the inlet, and the other end of the connecting sleeve is connected to one end of the traction stub in a rotatable manner. The present disclosure further discloses an optical fiber connector assembly, a fiber plug, and a network device.
    Type: Application
    Filed: February 11, 2019
    Publication date: June 6, 2019
    Inventors: Xiongwei YAN, Wenxin WU, Yuliang WANG, Xuesong HUANG
  • Patent number: 10215929
    Abstract: The present disclosure discloses a plug protection cap that includes a main body, a connecting sleeve, and a traction stub. An accommodating cavity is disposed in the main body. An inlet is through the accommodating cavity that is disposed on an end face of one end of the main body. A locking part is disposed at a position that is on an inner circumferential surface of the accommodating cavity and that is near the inlet. One end of the connecting sleeve detachably sheathes one end that is of the main body and that is away from the inlet, and the other end of the connecting sleeve is rotatably connected to one end of the traction stub. The present disclosure further discloses an optical fiber connector assembly, a fiber plug, and a network device.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: February 26, 2019
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Xiongwei Yan, Wenxin Wu, Yuliang Wang, Xuesong Huang
  • Patent number: 9933583
    Abstract: An optical fiber connector includes a main body (1), a sleeve (2), and a plug (3). The main body (1) includes a first cube and a second cube that are formed by means of injection molding, where a first cavity (1o) is disposed inside the first cube, and the first cavity (1o) is used to adapt to an optical fiber sub-assembly inserted from a first end face of the first cube; at least two hook-like structures (1n) are formed, by means of injection molding, on the first cube extending from a second end face that is parallel to the first end face into the first cavity (1o), and the hook-like structures (1n) are used to tightly lock the optical fiber sub-assembly when the optical fiber sub-assembly is inserted from the first end face.
    Type: Grant
    Filed: July 14, 2016
    Date of Patent: April 3, 2018
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Xiongwei Yan, Xiaobo Lan, Xin Fu, Jianpeng Hu, Shirong Chen, Yu Xiong
  • Publication number: 20180081122
    Abstract: The present disclosure discloses a plug protection cap that includes a main body, a connecting sleeve, and a traction stub. An accommodating cavity is disposed in the main body. An inlet is through the accommodating cavity that is disposed on an end face of one end of the main body. A locking part is disposed at a position that is on an inner circumferential surface of the accommodating cavity and that is near the inlet. One end of the connecting sleeve detachably sheathes one end that is of the main body and that is away from the inlet, and the other end of the connecting sleeve is rotatably connected to one end of the traction stub. The present disclosure further discloses an optical fiber connector assembly, a fiber plug, and a network device.
    Type: Application
    Filed: November 17, 2017
    Publication date: March 22, 2018
    Inventors: Xiongwei YAN, Wenxin WU, Yuliang WANG, Xuesong HUANG
  • Publication number: 20160320567
    Abstract: An optical fiber connector includes a main body (1), a sleeve (2), and a plug (3).The main body (1) includes a first cube and a second cube that are formed by means of injection molding, where a first cavity (1o) is disposed inside the first cube, and the first cavity (1o) is used to adapt to an optical fiber sub-assembly inserted from a first end face of the first cube; at least two hook-like structures (1n) are formed, by means of injection molding, on the first cube extending from a second end face that is parallel to the first end face into the first cavity (1o), and the hook-like structures (1n) are used to tightly lock the optical fiber sub-assembly when the optical fiber sub-assembly is inserted from the first end face.
    Type: Application
    Filed: July 14, 2016
    Publication date: November 3, 2016
    Inventors: Xiongwei Yan, Xiaobo Lan, Xin Fu, Jianpeng Hu, Shirong Chen, Yu Xiong
  • Publication number: 20140179901
    Abstract: Polypeptides labelled with a donor and acceptor pair of dyes selected from a dibenzorhodamine dye and a diamino-benzophenoxazine dye are peptide conjugates which are useful for intracellular and bead-based assays with fluorescence detection. Peptide conjugates with a caspase-recognition site undergo cleavage into peptide fragments which may be detected, located, and quantitated by the changes in fluorescence. Intracellular cleavage of peptide conjugates is correlated with apoptosis.
    Type: Application
    Filed: December 11, 2013
    Publication date: June 26, 2014
    Applicant: APPLIED BIOSYSTEMS, LLC
    Inventors: Xiongwei YAN, Sheri Miraglia, Pau Miau Yuan
  • Patent number: 8623995
    Abstract: Polypeptides labelled with a donor and acceptor pair of dyes selected from a dibenzorhodamine dye and a diamino-benzophenoxazine dye are peptide conjugates which are useful for intracellular and bead-based assays with fluorescence detection. Peptide conjugates with a caspase-recognition site undergo cleavage into peptide fragments which may be detected, located, and quantitated by the changes in fluorescence. Intracellular cleavage of peptide conjugates is correlated with apoptosis.
    Type: Grant
    Filed: June 14, 2010
    Date of Patent: January 7, 2014
    Assignee: Applied Biosystems, LLC
    Inventors: Xiongwei Yan, Sheri Miraglia, Pau Miau Yuan
  • Patent number: 8501498
    Abstract: This invention pertains to methods, mixtures, kits and/or compositions for the determination of analytes by mass analysis using unique labeling reagents or sets of unique labeling reagents. The labeling reagents can be isomeric or isobaric and can be used to produce mixtures suitable for multiplex analysis of the labeled analytes.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: August 6, 2013
    Assignee: DH Technologies Development Pte. Ltd.
    Inventors: Xiongwei Yan, Pau-Miau Yuan, Sylvia W. Yuen, Kuo-Liang Hsi, Joe Y. Lam, Krishna G. Upadhya, Subhakar Dey, Darryl J. C. Pappin, Sasi Pillai, Helena Huang, Subhasish Purkayastha
  • Patent number: 8003767
    Abstract: Fluorescent, sulfonated 3,7-diamino-[8,9]benzophenoxazine dyes are provided that are especially useful for labelling biopolymers and other substrates. The dye-labelled conjugates can be used in a variety of contexts, including cell surface assays employing intact, live cells and in nucleic acid detection methods. The new dyes are water soluble and can be conjugated to a variety of substrates, such as polynucleotides, nucleosides, nucleotides, peptides, proteins, antibodies, carbohydrates, ligands, particles and surfaces.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: August 23, 2011
    Assignee: Applied Biosystems, LLC
    Inventors: Xiongwei Yan, Pau Miau Yuan
  • Patent number: 7995703
    Abstract: A method for controlling automatic X-ray exposure in an X-ray CT system includes establishing a correspondence table or function relationship between a ratio factor and an offset of a geometrical center of a scanned section, wherein the ratio factor represents a ratio of the projection area value when the geometrical center of the scanned section of a subject deviates from a rotation center to the standard projection area value when the geometrical center of the scanned section of the subject locates at the rotation center, scout scanning the subject, and calculating a “measured projection area value” and Projection Measure based on the scout scan data, calculating the offset of the geometrical center of the scanned section from the rotation center, substituting the offset into the correspondence table or function relationship to obtain a corresponding ratio factor, calculating the standard projection area value based on the ratio factor and the measured projection area value, and automatically determining by
    Type: Grant
    Filed: December 23, 2008
    Date of Patent: August 9, 2011
    Assignee: GE Medical Systems Global Technology Company, LLC
    Inventor: Xiongwei Yan
  • Publication number: 20110097758
    Abstract: Polypeptides labelled with a donor and acceptor pair of dyes selected from a dibenzorhodamine dye and a diamino-benzophenoxazine dye are peptide conjugates which are useful for intracellular and bead-based assays with fluorescence detection. Peptide conjugates with a caspase-recognition site undergo cleavage into peptide fragments which may be detected, located, and quantitated by the changes in fluorescence. Intracellular cleavage of peptide conjugates is correlated with apoptosis.
    Type: Application
    Filed: June 14, 2010
    Publication date: April 28, 2011
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Xiongwei Yan, Sheri Miraglia, Pau Miau Yuan
  • Publication number: 20100311175
    Abstract: This invention pertains to methods, mixtures, kits and/or compositions for the determination of analytes by mass analysis using unique labeling reagents or sets of unique labeling reagents. The labeling reagents can be isomeric or isobaric and can be used to produce mixtures suitable for multiplex analysis of the labeled analytes.
    Type: Application
    Filed: November 13, 2009
    Publication date: December 9, 2010
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Xiongwei YAN, Pau Miau Yuan, Sylvia W. Yuen, Kuo-Liang Hsi, Joe Y. Lam, Krishna G. Upadhya, Subhakar Dey, Darryl J.C. Pappin, Sasi Pillai, Helena Huang, Subhasish Purkayastha
  • Publication number: 20100273943
    Abstract: Polypeptides labelled with a donor and acceptor pair of dyes selected from a dibenzorhodamine dye and a diamino-benzophenoxazine dye are peptide conjugates which are useful for intracellular and bead-based assays with fluorescence detection. Peptide conjugates with a caspase-recognition site undergo cleavage into peptide fragments which may be detected, located, and quantitated by the changes in fluorescence. Intracellular cleavage of peptide conjugates is correlated with apoptosis.
    Type: Application
    Filed: July 6, 2010
    Publication date: October 28, 2010
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Xiongwei YAN, Sheri Miraglia, Pau Miau Yuan
  • Publication number: 20100166138
    Abstract: An X-ray CT apparatus includes an X-ray irradiator which irradiates fan-beam X-rays; a multi-channel X-ray detector disposed to face the X-ray irradiator; a transmitted X-ray data collection device which scans a subject while rotating the X-ray irradiator and the X-ray detector to collect transmitted X-ray data of two or more views; a scan control device which controls the scan; and an image reconstruction device which reconstructs an image. The X-ray irradiator irradiates fan-beam X-rays which are deflected to one side of the center of rotation, the X-ray detector has the number of channels to cope with a spread of the fan-beam X-rays, and the scan control device allows the X-ray irradiator and the X-ray detector to conduct a scan of at least one rotation.
    Type: Application
    Filed: December 22, 2009
    Publication date: July 1, 2010
    Inventor: Xiongwei Yan
  • Publication number: 20090168951
    Abstract: A method for controlling automatic X-ray exposure in an X-ray CT system includes establishing a correspondence table or function relationship between a ratio factor and an offset of a geometrical center of a scanned section, wherein the ratio factor represents a ratio of the projection area value when the geometrical center of the scanned section of a subject deviates from a rotation center to the standard projection area value when the geometrical center of the scanned section of the subject locates at the rotation center, scout scanning the subject, and calculating a “measured projection area value” and Projection Measure based on the scout scan data, calculating the offset of the geometrical center of the scanned section from the rotation center, substituting the offset into the correspondence table or function relationship to obtain a corresponding ratio factor, calculating the standard projection area value based on the ratio factor and the measured projection area value, and automatically determining by
    Type: Application
    Filed: December 23, 2008
    Publication date: July 2, 2009
    Inventor: Xiongwei YAN