Patents by Inventor Xiping Niu
Xiping Niu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230193403Abstract: The disclosure relates to insecticidal toxin resistance management and screening of novel insecticidal toxin receptors for insect resistance. One embodiment relates to the isolation, characterization, compositions, and methods of use relating to polynucleotides encoding novel insecticidal toxin receptors and the polypeptides encoded thereby. The polynucleotides and polypeptides are useful in identifying or designing insect pest management strategies.Type: ApplicationFiled: March 9, 2021Publication date: June 22, 2023Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: SAMANTHA L GRIFFIN, JAMES M HASLER, DEIRDRE KAPKA-KITZMAN, USHA MUPPIRALA, MARK EDWARD NELSON, XIPING NIU
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Publication number: 20220267792Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a plant insect pest, such as Coleopteran, Hemiptera, or Lepidopteran plant pest, including a Diabrotica, Leptinotarsa, Phyllotreta, Acyrthosiphan, Bemisia, Halyomorpha, Nezara, or Spodoptera plant pest, decrease the expression of a target sequence in the pest. Disclosed are various target polynucleotides set forth in any one of SEQ ID NOS: 1-53 or 107-254 disclosed herein, or variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest and pest population by insect sterilization (i.e., male and female sterility, reduction of sperm count, egg production and viability) and mating-based sterile insect technique (SIT). Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.Type: ApplicationFiled: April 29, 2022Publication date: August 25, 2022Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: XU HU, BLISS MARIE KERNODLE, MOLLIE MARY MCMAHON, ADANE KASSA, XIPING NIU, JAMES KEVIN PRESNAIL, ALBERT L. LU, NINA RICHTMAN, JONATHAN WILLIAM ROBESON
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Publication number: 20210292778Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a plant insect pest, such as Coleopteran, Hemiptera, or Lepidopteran plant pest, including a Diabrotica, Leptinotarsa, Phyllotreta, Acyrthosiphan, Bemisia, Halyomorpha, Nezara, or Spodoptera plant pest, decrease the expression of a target sequence in the pest. Disclosed are various target polynucleotides set forth in any one of SEQ ID NOS: 1-398 disclosed herein, or variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest. Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.Type: ApplicationFiled: June 27, 2017Publication date: September 23, 2021Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: COURTNEY ANNE DAVIS-VOGEL, XU HU, XIPING NIU, AMIT SETHI
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Publication number: 20200231985Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a plant insect pest, such as Coleopteran, Hemiptera, or Lepidopteran plant pest, including a Diabrotica, Leptinotarsa, Phyllotreta, Acyrthosiphan, Bemisia, Halyomorpha, Nezara, or Spodoptera plant pest, decrease the expression of a target sequence in the pest. Disclosed are various target polynucleotides set forth in any one of SEQ ID NOS: 1-53 or 107-254 disclosed herein, or variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest and pest population by insect sterilization (i.e., male and female sterility, reduction of sperm count, egg production and viability) and mating-based sterile insect technique (SIT). Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.Type: ApplicationFiled: April 3, 2020Publication date: July 23, 2020Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: XU HU, BLISS MARIE KERNODLE, MOLLIE MARY MCMAHON, ADANE KASSA, XIPING NIU, JAMES KEVIN PRESNAIL, ALBERT L LU, NINA RICHTMAN, JONATHAN WILLIAM ROBESON
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Publication number: 20200176561Abstract: The present invention discloses a cellular structure of a silicon carbide UMOSFET device having surge voltage self-suppression and self-overvoltage protection capabilities. A p-well region of the cellular structure is divided into three layers; the top layer is on the left and right sides of a U-shaped trench and in contact with the U-shaped trench; the middle layer and the bottom layer are respectively constituted by two parts on the left and right sides of the cellular structure, and the left and right parts of the two are not in contact; the distances between the left and right parts of the middle layer and the vertical axis of the cellular structure are greater than the distances between the left and right parts of the bottom layer and the vertical axis of the cellular structure; that is, a JFET structure is introduced to a drain current path of the cellular structure.Type: ApplicationFiled: November 30, 2017Publication date: June 4, 2020Applicant: BEIJING CENTURY GOLDRAY SEMICONDUCTOR CO., LTD.Inventors: Jun YUAN, Weijiang NI, Tianyun Li, Mingshan Li, Miaoling Xu, Jingwei ZHANG, Xiping NIU, Anxin SUN
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Patent number: 10647995Abstract: The present invention relates generally to methods of molecular biology and gene silencing to control pests.Type: GrantFiled: June 16, 2016Date of Patent: May 12, 2020Assignees: PIONEER HI-BRED INTERNATIONAL, INC., E I DU PONT DE NEMOURS AND COMPANYInventors: Xu Hu, Bliss Marie Kernodle, Molly Mary McMahon, Adane Kassa, Xiping Niu, James Kevin Presnail, Albert L. Lu, Nina Richtman, Jonathan William Robeson
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Publication number: 20190292543Abstract: The present invention relates generally to methods of molecular biology and gene silencing to control pests.Type: ApplicationFiled: December 13, 2017Publication date: September 26, 2019Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: VIRGINIA CRANE, JOHN LINDSEY FLEXNER, XU HU, ADANE KASSA, ALBERT L. LU, XIPING NIU, ZAIQI PAN, AMIT SETHI, GUSUI WU
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Publication number: 20190185867Abstract: The present invention relates generally to methods of molecular biology and gene silencing to control pests.Type: ApplicationFiled: June 2, 2017Publication date: June 20, 2019Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: XU HU, XIPING NIU, NINA RICHTMAN
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Publication number: 20180155739Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a plant insect pest, such as Coleopteran, Hemiptera, or Lepidopteran plant pest, including a Diabrotica, Leptinotarsa, Phyllotreta, Acyrthosiphan, Bemisia, Halyomorpha, Nezara, or Spodoptera plant pest, decrease the expression of a target sequence in the pest. Disclosed are various target polynucleotides set forth in any one of SEQ ID NOS: 1-53 or 107-254 disclosed herein, or variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest and pest population by insect sterilization (i.e., male and female sterility, reduction of sperm count, egg production and viability) and mating-based sterile insect technique (SIT). Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.Type: ApplicationFiled: June 16, 2016Publication date: June 7, 2018Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: XU HU, BLISS MARIE KERNODLE, MOLLY MARY MCMAHON, ADANE KASSA, XIPING NIU, JAMES KEVIN PRESNAIL, ALBERT L. LU, NINA RICHTMAN, JONATHAN WILLIAM ROBESON
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Publication number: 20180135048Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a plant insect pest, such as a Coleopteran plant pest or a Diabrotica plant pest, decrease the expression of a target sequence in the pest. Disclosed are various target polynucleotides set forth in any one of SEQ ID NOS: 1-54 and 81-84 disclosed herein, or variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest (i.e., has insecticidal activity). Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.Type: ApplicationFiled: February 24, 2016Publication date: May 17, 2018Inventors: XU HU, Xiping NIU, James Kevin PRESNAIL, Nina RICHTMAN, Joe ZHAO
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Publication number: 20170253887Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a Diabrotica plant pest, decrease the expression of a target sequence in the pest. Disclosed are various target polynucleotides set forth in any one of SEQ ID NOS: disclosed herein, (but not including the forward and reverse primers.) or variants or fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest (i.e., has insecticidal activity). Plants, plant parts, bacteria and other host cells comprising the silencing elements, variants or fragments thereof, or complements thereof, are also provided.Type: ApplicationFiled: August 31, 2015Publication date: September 7, 2017Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E I DU PONT DE NEMOURS AND COMPANYInventors: XU HU, XIPING NIU, MEGHAN ONEAL, JAMES K. PRESNAIL, NINA RICHTMAN, JOE ZHAO
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Publication number: 20150267220Abstract: The present invention relates to the field of plant molecular biology, more particularly to the regulation of genes that increase drought tolerance and yield. Provided herein are methods finding use in agriculture for increasing drought tolerance in dicot and monocot plants. Methods comprising introducing into a plant cell a polynucleotide that encodes a maize XERICO polypeptide operably linked to a promoter that drives expression in a plant are provided. Methods are further provided for maintaining or increasing yield in plants under drought conditions by introducing into a plant cell a polynucleotide encoding a maize XERICO poly-peptide and a polynucleotide encoding an abscisic acid (ABA)-associated polypeptide. Also provided are transformed plants, plant tissues, plant cells, and seeds thereof.Type: ApplicationFiled: October 12, 2012Publication date: September 24, 2015Inventors: Norbert Brugiere, Jeffrey Habben, Xiping Niu
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Publication number: 20150007361Abstract: Methods and compositions for modulating plant development are provided. Polynucleotide sequences encoding ZmSNAC polypeptides are provided, as are the amino acid sequences of the encoded polypeptides. The sequences can be used in a variety of methods including modulating root development, modulating floral development, modulating leaf and/or shoot development, modulating senescence, modulating seed size and/or weight, and modulating tolerance of plants to abiotic stress. Transformed plants, plant cells, tissues, and seed are also provided. A stress-inducible ZmSNAC1 promoter is also provided.Type: ApplicationFiled: September 15, 2014Publication date: January 1, 2015Inventors: Nicholas J Bate, Xiping Niu
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Patent number: 8772043Abstract: Compositions and methods that allow for the rapid detection and accurate quantification of any polypeptides of interest are provided. Compositions include isolated polypeptides comprising at least one universal peptide tag, as well as isolated polynucleotides encoding such polypeptides. The universal peptide tags can be quantified by methods including, but not limited to, mass spectrometry, and can act as surrogates for determining the concentration of the polypeptides comprising the universal peptide tags. Methods provide for the detection and/or quantification of any polypeptides of interest that comprise at least one universal peptide tag, including methods using mass spectroscopy techniques. Methods are also provided for producing hosts, or cells or parts thereof, that comprise polypeptides comprising at least one universal peptide tag. Hosts, or cells, or parts thereof, include mammalian, bacterial, insect, yeast, viral or plant.Type: GrantFiled: December 22, 2011Date of Patent: July 8, 2014Assignee: Pioneer Hi Bred International IncInventors: Xuehua Hu, Michaela Owens, Clara Alarcon, Xiping Niu
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Publication number: 20140130206Abstract: The invention provides isolated pyruvate dehydrogenase kinase nucleic acids and their encoded polypeptides. The present invention provides methods and compositions relating to altering pyruvate dehydrogenase kinase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.Type: ApplicationFiled: January 10, 2014Publication date: May 8, 2014Applicants: PIONEER HI-BRED INTERNATIONAL INC, E I DU PONT DE NEMOURS AND COMPANYInventors: EDGAR B. CAHOON, REBECCA E. CAHOON, SAVERIO CARL FALCO, YIWEN FANG, SABINE S. HANTKE, ANTHONY J. KINNEY, JIAN-MING LEE, ZHONGSEN LI, GUO-HUA MIAO, MICHELE MORGANTE, XIPING NIU, JOAN T. ODELL, J ANTONI RAFALSKI, HAJIME SAKAI, PEIZHONG ZHENG, QUINN QUN ZHU
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Publication number: 20130007912Abstract: The invention provides isolated pyruvate dehydrogenase kinase nucleic acids and their encoded polypeptides. The present invention provides methods and compositions relating to altering pyruvate dehydrogenase kinase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.Type: ApplicationFiled: September 13, 2012Publication date: January 3, 2013Applicant: EI DU PONT DE NEMOURS AND COMPANY; AND PIONEER HI-BRED INTERNATIONAL INCInventors: Quinn Qun Zhu, Sabine S. Hantke, Xiping Niu, Zheng Peihong, Michele Morgante, Joan T. Odell, Saverio Carl Falco, Yiwen Fang, J. Antoni Rafalski, Hajime Sakai, Edgar B. Cahoon, Rebecca E. Cahoon, Jian-Ming Lee, Guo-Hua Miao, Zhongsen Li, Anthony J. Kinney
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Patent number: 8288616Abstract: The invention provides isolated pyruvate dehydrogenase kinase nucleic acids and their encoded polypeptides. The present invention provides methods and compositions relating to altering pyruvate dehydrogenase kinase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.Type: GrantFiled: May 12, 2011Date of Patent: October 16, 2012Assignee: E. I. du Pont de Nemours and CompanyInventors: Edgar Benjamin Cahoon, Rebecca E. Cahoon, Saverio Carl Falco, Yiwen Fang, Sabine S. Hantke, Anthony J. Kinney, Jian-Ming Lee, Zhongsen Li, Guo-Hua Miao, Michele Morgante, Xiping Niu, Joan T. Odell, J. Antoni Rafalski, Hajime Sakai, Peizhong Zheng, Quinn Qun Zhu
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Publication number: 20120167238Abstract: Compositions and methods that allow for the rapid detection and accurate quantification of any polypeptides of interest are provided. Compositions include isolated polypeptides comprising at least one universal peptide tag, as well as isolated polynucleotides encoding such polypeptides. The universal peptide tags can be quantified by methods including, but not limited to, mass spectrometry, and can act as surrogates for determining the concentration of the polypeptides comprising the universal peptide tags. Methods provide for the detection and/or quantification of any polypeptides of interest that comprise at least one universal peptide tag, including methods using mass spectroscopy techniques. Methods are also provided for producing hosts, or cells or parts thereof, that comprise polypeptides comprising at least one universal peptide tag. Hosts, or cells, or parts thereof, include mammalian, bacterial, insect, yeast, viral or plant.Type: ApplicationFiled: December 22, 2011Publication date: June 28, 2012Applicant: Pioneer Hi-Bred International, Inc.Inventors: Xuehua Hu, Michaela Owens, Clara Alarcon, Xiping Niu
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Patent number: 8124836Abstract: Compositions and methods for modulating abscisic acid (ABA) perception and signal transduction in developing seed are provided. The methods and compositions find use in increasing yield in plants, particularly under abiotic stress. Compositions comprise genetic constructs known to affect ABA sensitivity, particularly ABA biosynthetic mutants and fragments and variants thereof.Type: GrantFiled: February 13, 2009Date of Patent: February 28, 2012Assignee: Pioneer Hi-Bred International, Inc.Inventors: Nicholas J Bate, Xiping Niu
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Publication number: 20110214204Abstract: The invention provides isolated pyruvate dehydrogenase kinase nucleic acids and their encoded polypeptides. The present invention provides methods and compositions relating to altering pyruvate dehydrogenase kinase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.Type: ApplicationFiled: May 12, 2011Publication date: September 1, 2011Applicant: EI DU PONT DE NEMOURS AND COMPANY; AND PIONEER HI-BRED INTERNATIONAL INCInventors: Quinn Qun Zhu, Sabine S. Hantke, Xiping Niu, Zheng Peizhong, Michele Morgante, Joan T. Odell, Saverio Carl Falco, Yiwen Fang, J. Antoni Rafalski, Hajime Sakai, Edgar B. Cahoon, Rebecca E. Cahoon, Jian-Ming Lee, Guo-Hua Miao, Zhongsen Li, Anthony J. Kinney