Abstract: The present disclosure relates to a combined pharmaceutical composition containing a CDK4/6 inhibitor and a use thereof, and specifically relates to a combined pharmaceutical composition comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof and fulvestrant. The present disclosure further relates to a use of the combined pharmaceutical composition in treating breast cancer. The combined pharmaceutical composition of the present disclosure produces better therapeutic effects in reducing tumor growth or even eliminating tumors.

Abstract: A method for determining a regulation range of pumping power of a three-machine pumped storage unit is provided. The method includes: obtaining a first parameter set of pumping measurement parameters for characterizing the three-machine pumped storage unit and determining a pumping process efficiency; determining a first relational expression based on the pumping process efficiency and a design efficiency of a pumped storage power station and establishing a second relational expression; and determining a third relational expression based on power absorbed by a power grid and the second relational expression and determining a fourth relational expression, where the fourth relational expression reflects the regulation range of the pumping power of the three-machine pumped storage unit. The method for determining the regulation range of the pumping power of the three-machine pumped storage unit is proposed according to unit characteristics and operating economy of the power station.

Abstract: The present invention is a method for GPS positioning in a weak signal environment. The method includes obtaining assistance data for a GPS signal from a satellite at a predetermined time, wherein the assistance data including predicted navigation data, Doppler shift and Doppler shift rate and the GPS signal being modulated by a carrier signal, a pseudorandom code and navigation data, estimating a predicted receiving time for the GPS signal reaching the GPS receiver, capturing the GPS signal, converting the GPS signal to an intermediate frequency signal, acquiring a code phase of the pseudorandom code from the intermediate frequency signal by using the assistance data and the predicted receiving time, and obtaining a position for the GPS receiver based on the predicted navigation data and the code phase of the pseudorandom code.

Abstract: The present invention is a method for GPS positioning in a weak signal environment. The method includes obtaining assistance data for a GPS signal from a satellite at a predetermined time, wherein the assistance data including predicted navigation data, Doppler shift and Doppler shift rate and the GPS signal being modulated by a carrier signal, a pseudorandom code and navigation data, estimating a predicted receiving time for the GPS signal reaching the GPS receiver, capturing the GPS signal, converting the GPS signal to an intermediate frequency signal, acquiring a code phase of the pseudorandom code from the intermediate frequency signal by using the assistance data and the predicted receiving time, and obtaining a position for the GPS receiver based on the predicted navigation data and the code phase of the pseudorandom code.