Patents by Inventor Xiuchun Zhang

Xiuchun Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240051982
    Abstract: There are provided compounds of Formula (A) and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for the prevention or treatment in a manual of joint and bone disorders such as arthritis and osteoporosis.
    Type: Application
    Filed: June 20, 2023
    Publication date: February 15, 2024
    Inventors: Xianqi KONG, Jiasheng LU, Jiamin GU, Xiang JI, Daiqiang HU, Xiuchun ZHANG, Xinyong LV, Jinchao AI, Dongdong WU, Lin WANG, Dongqing ZHU, Xiaolin HE
  • Publication number: 20230295079
    Abstract: There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-? related diseases, such as Alzheimer's disease.
    Type: Application
    Filed: November 23, 2022
    Publication date: September 21, 2023
    Inventors: Jiasheng LU, Jiamin GU, Xinyong LV, Guowei SONG, Dongdong WU, Daiqiang HU, Jun GU, Gang CHEN, Xiang JI, Xiuchun ZHANG, Jinchao AI, Xianqi KONG
  • Patent number: 11718636
    Abstract: There are provided compounds of Formula (A) and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for the prevention or treatment in a mammal of joint and bone disorders such as arthritis and osteoporosis.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: August 8, 2023
    Assignee: RISEN (SUZHOU) PHARMA TECH CO., LTD.
    Inventors: Xianqi Kong, Jiasheng Lu, Jiamin Gu, Xiang Ji, Daiqiang Hu, Xiuchun Zhang, Xinyong Lv, Jinchao Ai, Dongdong Wu, Lin Wang, Dongqing Zhu, Xiaolin He
  • Publication number: 20230227488
    Abstract: There are provided compounds of Formula (A) and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for the prevention or treatment in a mammal of joint and bone disorders such as arthritis and osteoporosis.
    Type: Application
    Filed: January 18, 2023
    Publication date: July 20, 2023
    Inventors: Jiasheng LU, Jiamin GU, Xiang JI, Daiqiang HU, Xiuchun ZHANG, Xinyong LV, Jinchao AI, Dongdong WU, Xianqi KONG, LIN WANG, Dongqing ZHU, Xiaolin HE
  • Publication number: 20230115907
    Abstract: A heterocyclic compound, and a pharmaceutical composition thereof, a preparation method therefor, an intermediate thereof and an application thereof. The structure of the heterocyclic compound is as shown in formula (I) below. The compound has CDK7 inhibitory activity, and can be used to treat tumors and other diseases.
    Type: Application
    Filed: December 18, 2020
    Publication date: April 13, 2023
    Inventors: Yonghan HU, Dongdong WU, Wei PENG, Xiuchun ZHANG, Yuchuan WU
  • Patent number: 11591358
    Abstract: There are provided compounds of Formula (A) and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for the prevention or treatment in a mammal of joint and bone disorders such as arthritis and osteoporosis.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: February 28, 2023
    Assignee: RISEN (SUZHOU) PHARMA TECH CO., LTD.
    Inventors: Jiasheng Lu, Jiamin Gu, Xiang Ji, Daiqiang Hu, Xiuchun Zhang, Xinyong Lv, Jinchao Al, Dongdong Wu, Xianqi Kong, Lin Wang, Dongqing Zhu, Xiaolin He
  • Publication number: 20210347731
    Abstract: There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-? related diseases, such as Alzheimer's disease.
    Type: Application
    Filed: January 4, 2021
    Publication date: November 11, 2021
    Inventors: Jiasheng LU, Jiamin GU, Xinyong LV, Guowei SONG, Dongdong WU, Daiqiang HU, Jun GU, Gang CHEN, Xiang JI, Xiuchun ZHANG, Jinchao AI, Xianqi KONG
  • Patent number: 10954188
    Abstract: There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-? related diseases, such as Alzheimer's disease.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: March 23, 2021
    Assignee: RISEN (SUZHOU) PHARMA TECH CO., LTD.
    Inventors: Jiasheng Lu, Jiamin Gu, Xinyong Lv, Guowei Song, Dongdong Wu, Daiqiang Hu, Jun Gu, Gang Chen, Xiang Ji, Xiuchun Zhang, Jinchao Ai, Xianqi Kong
  • Publication number: 20210079033
    Abstract: There are provided compounds of Formula (A) and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for the prevention or treatment in a mammal of joint and bone disorders such as arthritis and osteoporosis.
    Type: Application
    Filed: December 17, 2018
    Publication date: March 18, 2021
    Inventors: Xianqi KONG, Jiasheng LU, Jiamin GU, Xiang JI, Daiqiang HU, Xiuchun ZHANG, Xinyong LV, Jinchao AI, Dongdong WU, Lin WANG, Dongqing ZHU, Xiaolin HE
  • Patent number: 10881681
    Abstract: CD73 (also known as ecto-5?-nucleotidase) inhibitor compounds are provided, as well as compositions and uses thereof for treating or preventing CD73-associated or related diseases, disorders and conditions, including cancer- and immune-related disorders. CD73 inhibitor compounds include compounds having the structure set forth in Formula I and pharmaceutically acceptable esters or salts thereof.
    Type: Grant
    Filed: September 10, 2019
    Date of Patent: January 5, 2021
    Assignee: RISEN (SUZHOU) PHARMA TECH CO., LTD.
    Inventors: Jiasheng Lu, Jiamin Gu, Dongdong Wu, Gang Chen, Chengyong Sun, Xiang Ji, Lin Wang, Feng Zhou, Xiuchun Zhang, Xianqi Kong
  • Publication number: 20200223793
    Abstract: There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-? related diseases, such as Alzheimer's disease.
    Type: Application
    Filed: October 17, 2019
    Publication date: July 16, 2020
    Inventors: Jiasheng LU, Jiamin GU, Xinyong LV, Guowei SONG, Dongdong WU, Daiqiang HU, Jun GU, Gang CHEN, Xiang JI, Xiuchun ZHANG, Jinchao AI, Xianqi KONG
  • Publication number: 20200078388
    Abstract: CD73 (also known as ecto-5?-nucleotidase) inhibitor compounds are provided, as well as compositions and uses thereof for treating or preventing CD73-associated or related diseases, disorders and conditions, including cancer- and immune-related disorders. CD73 inhibitor compounds include compounds having the structure set forth in Formula I and pharmaceutically acceptable esters or salts thereof.
    Type: Application
    Filed: September 10, 2019
    Publication date: March 12, 2020
    Inventors: Jiasheng LU, Jiamin GU, Dongdong WU, Gang CHEN, Chengyong SUN, Xiang JI, Lin WANG, Feng ZHOU, Xiuchun ZHANG, Xianqi KONG
  • Patent number: 10472323
    Abstract: There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-? related diseases, such as Alzheimer's disease.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: November 12, 2019
    Assignee: RISEN (SUZHOU) PHARMA TECH CO., LTD.
    Inventors: Jiasheng Lu, Jiamin Gu, Xinyong Lv, Guowei Song, Dongdong Wu, Daiqiang Hu, Jun Gu, Gang Chen, Xiang Ji, Xiuchun Zhang, Jinchao Ai, Xianqi Kong
  • Publication number: 20190185502
    Abstract: There are provided compounds of Formula (A) and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for the prevention or treatment in a mammal of joint and bone disorders such as arthritis and osteoporosis.
    Type: Application
    Filed: December 17, 2018
    Publication date: June 20, 2019
    Inventors: Jiasheng LU, Jiamin GU, Xiang JI, Daiqiang HU, Xiuchun ZHANG, Xinyong LV, Jinchao AI, Dongdong WU, Xianqi KONG, Lin WANG, Dongqing ZHU, Xiaolin HE
  • Publication number: 20180273471
    Abstract: There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-? related diseases, such as Alzheimer's disease.
    Type: Application
    Filed: March 31, 2017
    Publication date: September 27, 2018
    Inventors: Jiasheng Lu, Jiamin Gu, Xinyong Lv, Guowei Song, Dongdong Wu, Daiqiang Hu, Jun Gu, Gang Chen, Xiang Ji, Xiuchun Zhang, Jinchao Ai, Xianqi Kong