Abstract: Provided in the present application are markers for predicting Coronavirus disease 2019 (COVID-19) immune checkpoint storm, an application and a kit thereof, and a preparation method of the kit, belonging to the technical field of biomedicine. The markers of the present application comprise one or more of BTLA, GITR, HVEM, IDO, LAG-3, PD-1, PD-L1, TIM-3, CD28, CD80, 4-1BB, CD27, and CD152. Predicting the COVID-19 immune checkpoint storm by using the biomarkers provided by the present application or the kit prepared therefrom has the advantages of rapid and accurate detection at low cost, and has a broad prospect of application.

Abstract: A method for manufacturing thin strip continuously cast 700 Mpa grade high strength weather-resistant steel, the method comprising the following steps: 1) casting a 1-5 mm thick cast strip in a double roller continuous casting machine, the cast strip comprising the following chemical compositions by weight percent: C 0.03-0.1%, Si?0.4%, Mn 0.75-2.0%, P 0.07-0.22%, S?0.01%, N?0.012%, and Cu 0.25-0.8%, further comprising more than one of Nb, V, Ti and Mo: Nb 0.01-0.1%, V 0.01-0.1%, Ti 0.01-0.1%, and Mo 0.1-0.5%, and the balance being Fe and unavoidable impurities; 2) cooling the cast strip at a rate greater than 20° C./s; 3) hot rolling the cast strip under a temperature of 1050-1250° C. at a reduction rate of 20-50% and a deformation rate greater than 20 s?1; then conducting austenite online recrystallization, the thickness of the hot rolled strip being 0.5-3.0 mm; 4) cooling at a rate of 10-80° C./s; and 5) rolling up under a temperature of 500-650° C.

Abstract: A manufacturing method for strip casting 550 MPa-grade high strength atmospheric corrosion-resistant steel strip, comprising the following steps: 1) smelting, where the chemical composition of a molten steel is that: C is between 0.03-0.08%, Si?0.4%, Mn is between 0.6-1.5%, P is between 0.07-0.22%, S?0.01%, N?0.012%, Cu is between 0.25-0.8%, Cr is between 0.3-0.8%, and Ni is between 0.12-0.4%, additionally, also comprised is at least one micro-alloying element among Nb, V, Ti, and Mo, where Nb is between 0.01-0.08%, V is between 0.01-0.08%, Ti is between 0.01-0.08%, and Mo is between 0.1-0.4%, and where the remainder is Fe and unavoidable impurities; 2) strip casting, where a 1-5 mm-thick cast strip is casted directly; 3) cooling the strip, where the cooling rate is greater than 20° C./s; 4) online hot rolling the cast strip, where the hot rolling temperature is between 1050-1250° C.

Abstract: A manufacturing method for strip casting 700 MPa-grade high strength atmospheric corrosion-resistant steel, comprising the following steps: 1) smelting, where the chemical composition of a molten steel in terms of weight percentage is that C is between 0.03-0.1%, Si?0.4%, Mn is between 0.75-2.0%, P is between 0.07-0.22%, S?0.01%, N?0.012%, Cu is between 0.25-0.8%, Cr is between 0.3-0.8%, and Ni is between 0.12-0.4%, additionally, also comprised is at least one micro-alloying element among Nb, V, Ti, and Mo, where Nb is between 0.01-0.1%, V is between 0.01-0.1%, Ti is between 0.01-0.1%, and Mo is between 0.1-0.5%, and where the remainder is Fe and unavoidable impurities; 2) strip casting, where a 1-5 mm-thick cast strip is casted directly; 3) cooling the cast strip, where the cooling rate is greater than 20° C./s; 4) online hot rolling the cast strip, where the hot rolling temperature is between 1050-1250° C.

Abstract: A manufacturing method for strip casting 550 MPa-grade high strength atmospheric corrosion-resistant steel strip, comprising the following steps: 1) smelting, where the chemical composition of a molten steel is that: C is between 0.03-0.08%, Si?0.4%, Mn is between 0.6-1.5%, P is between 0.07-0.22%, S?0.01%, N?0.012%, Cu is between 0.25-0.8%, Cr is between 0.3-0.8%, and Ni is between 0.12-0.4%, additionally, also comprised is at least one micro-alloying element among Nb, V, Ti, and Mo, where Nb is between 0.01-0.08%, V is between 0.01-0.08%, Ti is between 0.01-0.08%, and Mo is between 0.1-0.4%, and where the remainder is Fe and unavoidable impurities; 2) strip casting, where a 1-5 mm-thick cast strip is casted directly; 3) cooling the strip, where the cooling rate is greater than 20° C./s; 4) online hot rolling the cast strip, where the hot rolling temperature is between 1050-1250° C.

Abstract: A manufacturing method for strip casting 700 MPa-grade high strength atmospheric corrosion-resistant steel, comprising the following steps: 1) smelting, where the chemical composition of a molten steel in terms of weight percentage is that C is between 0.03-0.1%, Si?0.4%, Mn is between 0.75-2.0%, P is between 0.07-0.22%, S?0.01%, N?0.012%, Cu is between 0.25-0.8%, Cr is between 0.3-0.8%, and Ni is between 0.12-0.4%, additionally, also comprised is at least one micro-alloying element among Nb, V, Ti, and Mo, where Nb is between 0.01-0.1%, V is between 0.01-0.1%, Ti is between 0.01-0.1%, and Mo is between 0.1-0.5%, and where the remainder is Fe and unavoidable impurities; 2) strip casting, where a 1-5 mm-thick cast strip is casted directly; 3) cooling the cast strip, where the cooling rate is greater than 20° C./s; 4) online hot rolling the cast strip, where the hot rolling temperature is between 1050-1250° C.

Abstract: A method for manufacturing thin strip continuously cast 700 Mpa grade high strength weather-resistant steel, the method comprising the following steps: 1) casting a 1-5 mm thick cast strip in a double roller continuous casting machine, the cast strip comprising the following chemical compositions by weight percent: C 0.03-0.1%, Si?0.4%, Mn 0.75-2.0%, P 0.07-0.22%, S?0.01%, N?0.012%, and Cu 0.25-0.8%, further comprising more than one of Nb, V, Ti and Mo: Nb 0.01-0.1%, V 0.01-0.1%, Ti 0.01-0.1%, and Mo 0.1-0.5%, and the balance being Fe and unavoidable impurities; 2) cooling the cast strip at a rate greater than 20° C./s; 3) hot rolling the cast strip under a temperature of 1050-1250° C. at a reduction rate of 20-50% and a deformation rate greater than 20 s-1; then conducting austenite online recrystallization, the thickness of the hot rolled strip being 0.5-3.0 mm; 4) cooling at a rate of 10-80° C./s; and 5) rolling up under a temperature of 500-650° C.